Patents by Inventor Jingyu Xu
Jingyu Xu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250116192Abstract: The embodiments of the present disclosure provide an asymmetric hydraulic support for pseudo inclined mining in steeply dipping seam, wherein the asymmetric hydraulic support includes a top mechanism, a bottom mechanism, a telescopic mechanism, and a connecting mechanism; the top mechanism and the bottom mechanism are disposed in parallel to each other, and a projection of the top mechanism and the bottom mechanism on a working surface is a parallelogram, and a sum of an acute angle of each of two parallelograms and a steeply dipping angle in pseudo inclined mining is 90°; the telescopic mechanism is provided between the top mechanism and the bottom mechanism, and two ends of the telescopic mechanism are rotationally connected to the top mechanism and the bottom mechanism, respectively; one end of the two sets of connecting structures of the connecting mechanism is hinged by a first articulating shaft, and a central axis of the first articulating shaft is located in a middle of the top mechanism and the bottoType: ApplicationFiled: October 8, 2024Publication date: April 10, 2025Applicant: XI'AN UNIVERSITY OF SCIENCE AND TECHNOLOGYInventors: Yongping WU, Yuqian DU, Panshi XIE, Zhuangzhuang YAN, Tao HU, Bosheng HU, Yepeng TANG, Jingyu HUANGFU, Tong WANG, Yingrui XU
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Publication number: 20240390395Abstract: An ion channel blocker for treatment and/or prevention of hepatic fibrosis is provided. Based on the fact that the activation of hepatic stellate cells is an important link in anti-hepatic fibrosis, it is found that gliclazide has the effect of inhibiting the activation of hepatic stellate cells by in vitro and in vivo experiments. Further exploration reveals that gliclazide mainly inhibits the activation of hepatic stellate cells by inhibiting autophagy pathways, and thus the gliclazide can be used to prepare medicaments for treatment and/or prevention of hepatic fibrosis.Type: ApplicationFiled: September 14, 2023Publication date: November 28, 2024Inventors: Jingyu Xu, Rui Xie, Qian Du, Yanxia Hu, Jianhong Ding, Xianli Wu, Xiaoxu Yang, Jun Lou, Qi Liu, Zhuo Li
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APPLICATION OF CHANNEL BLOCKER IN PREPARATION OF DRUGS FOR TREATING AND/OR PREVENTING LIVER FIBROSIS
Publication number: 20240390329Abstract: An application of a channel blocker in preparation of drugs for treating and/or preventing liver fibrosis is provided, belonging to the field of biomedical technology. A new use of phenytoin sodium is provided. It is demonstrated that at the cell level, the phenytoin sodium can improve liver fibrosis by regulating autophagy and thus affecting the activation of hepatic stellate cells. In this situation, the efficacy of the phenytoin sodium on liver fibrosis is verified at the animal level by establishing a disease model, and the phenytoin sodium can be used to prepare drugs for treating and/or preventing liver fibrosis.Type: ApplicationFiled: September 6, 2023Publication date: November 28, 2024Inventors: Rui Xie, Jingyu Xu, Guowei Gong, Qian Du, Yanxia Hu, Jianhong Ding, Xianli Wu, Xiaoxu Yang, Jun Lou, Qi Liu, Zhuo Li -
Publication number: 20240390308Abstract: An application of potassium ion (K+) channel blocker in preparation of drugs for treating liver fibrosis is provided, which relates to the field of medical technologies. The K+ channel blocker is sotalol, the sotalol is originally used as an antiarrhythmic drug in clinic and has a property of inhibiting K+ channels. Experiments show that sotalol can effectively inhibit liver fibrosis and reduce expression of fibrosis-related protein alpha-smooth muscle actin (?-SMA), specifically by regulating expression and/or function of autophagy and epithelial-mesenchymal transition (EMT) molecules to achieve inhibition of hepatic stellate cell (HSC) fibrosis, so as to provide a new drug choice for clinical treatment of the liver fibrosis.Type: ApplicationFiled: July 6, 2023Publication date: November 28, 2024Inventors: Rui Xie, Jingyu Xu, Qian Du, Yanxia Hu, Jianhong Ding, Xianli Wu, Xiaoxu Yang, Jun Lou, Qi Liu, Zhuo Li
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Patent number: 12147431Abstract: A method for pushing a resource includes obtaining a collection of users to which a resource is to be pushed, in which the collection includes a plurality of users; obtaining respective predicted conversion rates of the resource for the plurality of users; obtaining user groups by dividing the plurality of users into groups based on respective predicted conversion rates for the plurality of users, in which the user groups correspond to different conversion rate ranges; and for each user group, selecting a target user from the user group based on a real conversion rate related to pushed users corresponding to the conversion rate range of the user group, and pushing the resource to the target user.Type: GrantFiled: December 1, 2022Date of Patent: November 19, 2024Assignee: BEIJING BAIDU NETCOM SCIENCE TECHNOLOGY CO., LTD.Inventors: Haocheng Liu, Jingyu Xu
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Publication number: 20230145408Abstract: A method of processing a feature information is provided, which relates to a field of data processing, in particular to fields of artificial intelligence and big data. The method includes: determining at least one candidate division point in a value range of the feature information, and determining an information value corresponding to each candidate division point; determining a target division point based on the information value; dividing the value range based on the target division point, so as to obtain two sub-ranges; determining a sub-range meeting a termination condition in the two sub-ranges as a target interval, determining a sub-range not meeting the termination condition in the two sub-ranges as a new value range, and returning to perform the step of determining at least one candidate division point in a value range until both sub-ranges meet the termination condition, so as to obtain a plurality of target intervals.Type: ApplicationFiled: December 29, 2022Publication date: May 11, 2023Inventors: Haocheng LIU, Jingyu XU, Cai CHEN, Shuo LI
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Publication number: 20230095947Abstract: A method for pushing a resource includes obtaining a collection of users to which a resource is to be pushed, in which the collection includes a plurality of users; obtaining respective predicted conversion rates of the resource for the plurality of users; obtaining user groups by dividing the plurality of users into groups based on respective predicted conversion rates for the plurality of users, in which the user groups correspond to different conversion rate ranges; and for each user group, selecting a target user from the user group based on a real conversion rate related to pushed users corresponding to the conversion rate range of the user group, and pushing the resource to the target user.Type: ApplicationFiled: December 1, 2022Publication date: March 30, 2023Applicant: BEIJING BAIDU NETCOM SCIENCE TECHNOLOGY CO., LTD.Inventors: Haocheng Liu, Jingyu Xu
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Patent number: 10796062Abstract: The independent claims of this patent signify a concise description of embodiments. Embodiments described herein are directed to a database-driven scheme for automating the process of VDRC checking in a full-custom EDA Design and Implementation tool.Type: GrantFiled: May 25, 2018Date of Patent: October 6, 2020Assignee: SYNOPSYS, INC.Inventors: Nabil Yazdani, Donald Oriordan, Jingyu Xu, Bulent Basaran, Larissa Nitchougovskaia
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Patent number: 10372867Abstract: Techniques for analyzing a routed interconnection of a net of a circuit are discussed herein. Some embodiments may include a method comprising with a computer, analyzing the circuit to determine a performance parameter of the net, wherein the circuit is analyzed based at least in part on applying pre-layout simulation data of the net to layout data of the circuit. Additionally or alternatively, the circuit may be analyzed based on extracting characteristics of the routed interconnection from the layout data of the net.Type: GrantFiled: September 2, 2015Date of Patent: August 6, 2019Assignee: SYNOPSYS, INC.Inventors: Jun Wang, Randy Bishop, Jingyu Xu, Dick Liu, Hu Cai, Jun Lu
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Publication number: 20180341742Abstract: The independent claims of this patent signify a concise description of embodiments. Embodiments described herein are directed to a database-driven scheme for automating the process of VDRC checking in a full-custom EDA Design and Implementation tool.Type: ApplicationFiled: May 25, 2018Publication date: November 29, 2018Inventors: Nabil Yazdani, Donald Oriordan, Jingyu Xu, Bulent Basaran, Larissa Nitchougovskaia
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Patent number: 10078721Abstract: Systems and techniques are described for determining a resistance of a conducting structure. The conducting structure can be partitioned into a set of polygons based on (1) equipotential lines and (2) boundaries of the conducting structure. Next, a matrix equation can be constructed, wherein for at least one polygon in the set of polygons, electric potentials of boundary elements on the boundaries of the polygon are represented by linear combinations of electric potentials of two or more equipotential lines. The resistance of the conducting structure can then be determined by solving the matrix equation.Type: GrantFiled: June 3, 2016Date of Patent: September 18, 2018Assignee: Synopsys, Inc.Inventors: Xiaoxu Cheng, Jingyu Xu, Hau-Yung Chen, Dick Liu
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Patent number: 9901936Abstract: The present invention discloses a cyclone generator for a pipeline type oil-water separator which separates oil from water using the principle of cyclone. The cyclone generator comprises: flow deflectors which are fixedly arranged along the circumferential direction of a pipe to generate, when an oil-water mixture flows through the flow deflectors, a centrosymmetric cyclone field to centrifugally separate oil from water. The present invention further discloses an oil-water separation device which uses the aforementioned principle, the mixture of oil and water flowing through the device forms a centrosymmetric cyclone field in which an oil core is distributed in the central area of a pipe without shifting significantly so as to achieve an excellent oil-water separation effect.Type: GrantFiled: February 22, 2012Date of Patent: February 27, 2018Assignee: INSTITUTE OF MECHANICS, CHINESE ACADEMY OF SCIENCESInventors: Yingxiang Wu, Jingyu Xu, Shiying Shi, Jun Guo, Jun Zhang
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Publication number: 20170351803Abstract: Systems and techniques are described for determining a resistance of a conducting structure. The conducting structure can be partitioned into a set of polygons based on (1) equipotential lines and (2) boundaries of the conducting structure. Next, a matrix equation can be constructed, wherein for at least one polygon in the set of polygons, electric potentials of boundary elements on the boundaries of the polygon are represented by linear combinations of electric potentials of two or more equipotential lines. The resistance of the conducting structure can then be determined by solving the matrix equation.Type: ApplicationFiled: June 3, 2016Publication date: December 7, 2017Applicant: Synopsys, Inc.Inventors: Xiaoxu Cheng, Jingyu Xu, Hau-Yung Chen, Dick Liu
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Publication number: 20170249415Abstract: Techniques for analyzing a routed interconnection of a net of a circuit are discussed herein. Some embodiments may include a method comprising with a computer, analyzing the circuit to determine a performance parameter of the net, wherein the circuit is analyzed based at least in part on applying pre-layout simulation data of the net to layout data of the circuit. Additionally or alternatively, the circuit may be analyzed based on extracting characteristics of the routed interconnection from the layout data of the net.Type: ApplicationFiled: September 2, 2015Publication date: August 31, 2017Inventors: Jun WANG, Randy BISHOP, Jingyu XU, Dick LIU, Hu CAI, Jun LU
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Publication number: 20170061064Abstract: Techniques for analyzing a routed interconnection of a net of a circuit are discussed herein. Some embodiments may include a method comprising with a computer, analyzing the circuit to determine a performance parameter of the net, wherein the circuit is analyzed based at least in part on applying pre-layout simulation data of the net to layout data of the circuit. Additionally or alternatively, the circuit may be analyzed based on extracting characteristics of the routed interconnection from the layout data of the net.Type: ApplicationFiled: September 2, 2015Publication date: March 2, 2017Inventors: Jun WANG, Randy BISHOP, Jingyu XU, Dick LIU, Hu CAI, Jun LU
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Patent number: 9228175Abstract: Described nucleic acid molecules (and corresponding peptides) encode lyso-phosphatidylcholine (LPC) acyltransferases. Over-expression of the LPC acyltransferases in a cell may lead to enhanced production of PUFA, or other unusual fatty acids, and/or to increased oil content in the cell.Type: GrantFiled: January 18, 2013Date of Patent: January 5, 2016Assignees: National Research Counsel of Canada, Dow AgroSciences LLCInventors: Qilin Chen, Jitao Zou, Zhifu Zheng, Jingyu Xu
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Patent number: 8993034Abstract: The present disclosure relates to the isolation, purification, and characterization of a diacylglycerol acyltransferase 2 (DGAT2), and genes encoding DGAT2, from algae. DGAT2 can incorporate very long-chain polyunsaturated fatty acids into triacylglycerol more efficiently than DGAT1. The disclosure concerns methods of regulating seed oil content, fatty acid synthesis and fatty acid composition using the DGAT2 gene and to tissues and plants transformed with the gene. The disclosure also relates to transgenic plants, plant tissues and plant seeds having a genome containing an introduced DNA sequence of the disclosure, and a method of producing such plants and plant seeds.Type: GrantFiled: February 24, 2014Date of Patent: March 31, 2015Assignees: Dow AgroSciences LLC, National Research Council CanadaInventors: Jitao Zou, Jingyu Xu, Zhifu Zheng
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Publication number: 20140330003Abstract: The present disclosure relates to the isolation, purification, and characterization of a diacylglycerol acyltransferase 2 (DGAT2), and genes encoding DGAT2, from algae. DGAT2 can incorporate very long-chain polyunsaturated fatty acids into triacylglycerol more efficiently than DGAT1. The disclosure concerns methods of regulating seed oil content, fatty acid synthesis and fatty acid composition using the DGAT2 gene and to tissues and plants transformed with the gene. The disclosure also relates to transgenic plants, plant tissues and plant seeds having a genome containing an introduced DNA sequence of the disclosure, and a method of producing such plants and plant seeds.Type: ApplicationFiled: February 24, 2014Publication date: November 6, 2014Applicants: Dow AgroSciences, LLC, National Research Council of CanadaInventors: Jitao Zou, Jingyu Xu, Zhifu Zheng
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Publication number: 20140138306Abstract: The present invention discloses a cyclone generator for a pipeline type oil-water separator which separates oil from water using the principle of cyclone. The cyclone generator comprises: flow deflectors which are fixedly arranged along the circumferential direction of a pipe to generate, when an oil-water mixture flows through the flow deflectors, a centrosymmetric cyclone field to centrifugally separate oil from water. The present invention further discloses an oil-water separation device which uses the aforementioned principle, the mixture of oil and water flowing through the device forms a centrosymmetric cyclone field in which an oil core is distributed in the central area of a pipe without shifting significantly so as to achieve an excellent oil-water separation effect.Type: ApplicationFiled: February 22, 2012Publication date: May 22, 2014Applicant: INSTITUTE OF MECHANICS, CHINESE ACADEMY OF SCIENCEInventors: Yingxiang Wu, Jingyu Xu, Shiying Shi, Jun Guo, Jun Zhang
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Patent number: 8658855Abstract: The present disclosure relates to the isolation, purification, and characterization of a diacylglycerol acyltransferase 2 (DGAT2), and genes encoding DGAT2, from algae. DGAT2 can incorporate very long chain polyunsaturated fatty acids in to triacylglycerol more efficiently than DGAT1. The disclosure concerns methods of regulating seed oil content, fatty acid synthesis and fatty acid composition using the DGAT2 gene and to tissues and plants transformed with the gene. The disclosure also relates to transgenic plants, plant tissues and plant seeds having a genome containing an introduced DNA sequence of the disclosure, and a method of producing such plants and plant seeds.Type: GrantFiled: December 16, 2008Date of Patent: February 25, 2014Assignees: National Research Council of Canada, Dow AgroSciences LLCInventors: Jitao Zou, Jingyu Xu, Zhifu Zheng