Patents by Inventor Jingyuan Ma

Jingyuan Ma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250091619
    Abstract: The disclosure relates to the technical field of autonomous driving, and provides a method for predicting a vehicle trajectory, a control apparatus, and a vehicle, to solve the problem of how to effectively deal with existing highly complex traffic scenario interactions and difficulties in iterative planning and control processes. In the method, scenario interaction results of a traffic agent are obtained based on a static environment perception result and a traffic agent perception result of a vehicle at a current moment, an initial interaction scenario is obtained based on the scenario interaction results, interaction scenario simulation is performed based on the initial interaction scenario and an ego vehicle driving decision to determine an optimal interaction scenario evolution feature of the traffic agent, and an optimal driving trajectory of the vehicle is obtained based on the optimal interaction scenario evolution feature and a state of the vehicle.
    Type: Application
    Filed: December 7, 2023
    Publication date: March 20, 2025
    Inventors: Haoyang FAN, Hailong QIN, Shaoqing REN, Jingyuan MA, Gang SUN, Shaohua ZHENG, Qiuyi LI, Xiaoxin FU
  • Publication number: 20250060020
    Abstract: The present invention discloses a vibration suppression system and method for a star simulation system using laser interference detection. The system includes a laser light source, a first beam splitter, a collimator set, a second beam splitter, a mirror, a detection convergent mirror assembly, a CCD detector, a computer control system, a jitter compensating mirror and a flat splitter; the optical path of the whole system includes a reference optical path and a detection compensating signal optical path. The reference optical path and the detection compensating signal optical path converge at the same time on the CCD detector to constitute a vibration detection interference optical path, and the computer control system performs feedback compensation according to the interferogram intensity change formed by the vibration detection interference optical path. Both the CCD detector and the jitter compensating mirror are connected to the computer control system.
    Type: Application
    Filed: October 20, 2022
    Publication date: February 20, 2025
    Inventors: Jinpeng LI, Xinrui WANG, Yongxing YANG, Saiya WANG, Yong MA, Jingyuan ZHANG, Yu HAN
  • Publication number: 20220324814
    Abstract: Disclosed herein are small molecule calpain modulator compositions, pharmaceutical compositions, the use and preparation thereof.
    Type: Application
    Filed: April 12, 2022
    Publication date: October 13, 2022
    Inventors: Brad Owen Buckman, John Beamond Nicholas, Shendong Yuan, Marc Adler, Kumaraswamy Emayan, Jingyuan Ma
  • Patent number: 11339130
    Abstract: Disclosed herein are small molecule calpain modulator compositions, pharmaceutical compositions, the use and preparation thereof.
    Type: Grant
    Filed: September 25, 2020
    Date of Patent: May 24, 2022
    Assignee: Blade Therapeutics, Inc.
    Inventors: Brad Owen Buckman, John Beamond Nicholas, Shendong Yuan, Marc Adler, Kumaraswamy Emayan, Jingyuan Ma
  • Patent number: 11292801
    Abstract: Disclosed herein are small molecule calpain modulator compositions, pharmaceutical compositions, the use and preparation thereof. Some embodiments relate to macrocyclic ?-keto amide derivatives and their use as therapeutic agents.
    Type: Grant
    Filed: June 29, 2017
    Date of Patent: April 5, 2022
    Assignee: Blade Therapeutics, Inc.
    Inventors: Brad Owen Buckman, Shendong Yuan, John Beamond Nicholas, Jingyuan Ma, Kumaraswamy Emayan, Marc Adler
  • Publication number: 20210347727
    Abstract: Small molecule calpain modulator compositions and pharmaceutical compositions can be prepared and used as therapeutic agents. Exemplary compositions include non-macrocyclic a-keto amide derivatives. The therarapeutic agents can be used for treating fibrotic disease or a resulting secondary disease state or condition. The small molecules can competitively bind with calpastatin and/or inhibit calpain through contact with CAPN1, CAPN2, and/or CAPN9 enzymes.
    Type: Application
    Filed: June 19, 2018
    Publication date: November 11, 2021
    Inventors: Brad Owen Buckman, Shendong Yuan, John Beamond Nicholas, Jingyuan Ma, Kumaraswamy Emayan, Marc Adler
  • Patent number: 10934261
    Abstract: Disclosed herein are small molecule calpain modulator compositions, pharmaceutical compositions, the use and preparation thereof.
    Type: Grant
    Filed: September 27, 2017
    Date of Patent: March 2, 2021
    Assignee: Blade Therapeutics, Inc.
    Inventors: Brad Owen Buckman, John Beamond Nicholas, Shendong Yuan, Marc Adler, Kumaraswamy Emayan, Jingyuan Ma
  • Patent number: 10894776
    Abstract: Disclosed herein are small molecule calpain modulator compositions, pharmaceutical compositions, the use and preparation thereof.
    Type: Grant
    Filed: September 27, 2017
    Date of Patent: January 19, 2021
    Assignee: Blade Therapeutics, Inc.
    Inventors: Brad Owen Buckman, John Beamond Nicholas, Shendong Yuan, Marc Adler, Kumaraswamy Emayan, Jingyuan Ma
  • Publication number: 20200392157
    Abstract: Disclosed herein are small molecule calpain modulator compositions, pharmaceutical compositions, the use and preparation thereof. Some embodiments relate to macrocyclic ?-keto amide derivatives and their use as therapeutic agents.
    Type: Application
    Filed: June 29, 2017
    Publication date: December 17, 2020
    Inventors: Brad Owen Buckman, Shendong Yuan, John Beamond Nicholas, Jingyuan Ma, Kumaraswamy Emayan, Marc Adler
  • Publication number: 20200123114
    Abstract: Disclosed herein are small molecule calpain modulator compositions, pharmaceutical compositions, the use and preparation thereof.
    Type: Application
    Filed: September 27, 2017
    Publication date: April 23, 2020
    Applicant: Blade Therapeutics, Inc.
    Inventors: Brad Owen BUCKMAN, John Beamond NICHOLAS, Shendong YUAN, Marc ADLER, Kumaraswamy EMAYAN, Jingyuan MA
  • Patent number: 9925189
    Abstract: Compounds and methods are provided for the treatment of, inter alia, Type II diabetes and other diseases associated with poor glycemic control. The compounds of the invention are orally active.
    Type: Grant
    Filed: July 26, 2017
    Date of Patent: March 27, 2018
    Assignee: CYMABAY THERAPEUTICS, INC.
    Inventors: Xin Chen, Peng Cheng, L. Edward Clemens, Jeffrey D. Johnson, Jingyuan Ma, Alison Murphy, Imad Nashashibi, Christopher J. Rabbat, Jiangao Song, Maria E. Wilson, Yan Zhu, Zuchun Zhao
  • Publication number: 20180021335
    Abstract: Compounds and methods are provided for the treatment of, inter alia, Type II diabetes and other diseases associated with poor glycemic control. The compounds of the invention are orally active.
    Type: Application
    Filed: July 26, 2017
    Publication date: January 25, 2018
    Inventors: Xin Chen, Peng Cheng, L. Edward Clemens, Jeffrey D. Johnson, Jingyuan Ma, Alison Murphy, Imad Nashashibi, Christopher J. Rabbat, Jiangao Song, Maria E. Wilson, Yan Zhu, Zuchun Zhao
  • Patent number: 9737537
    Abstract: Compounds and methods are provided for the treatment of, inter alia, Type II diabetes and other diseases associated with poor glycemic control. The compounds of the invention are orally active.
    Type: Grant
    Filed: October 25, 2016
    Date of Patent: August 22, 2017
    Assignee: CYMABAY THERAPEUTICS, INC.
    Inventors: Xin Chen, Peng Cheng, L. Edward Clemens, Jeffrey D. Johnson, Jingyuan Ma, Alison Murphy, Imad Nashashibi, Christopher J. Rabbat, Jiangao Song, Maria E. Wilson, Yan Zhu, Zuchun Zhao
  • Publication number: 20170105993
    Abstract: Compounds and methods are provided for the treatment of, inter alia, Type II diabetes and other diseases associated with poor glycemic control. The compounds of the invention are orally active.
    Type: Application
    Filed: October 25, 2016
    Publication date: April 20, 2017
    Inventors: Xin Chen, Peng Cheng, L. Edward Clemens, Jeffrey D. Johnson, Jingyuan Ma, Alison Murphy, Imad Nashashibi, Christopher J. Rabbat, Jiangao Song, Maria E. Wilson, Yan Zhu, Zuchun Zhao
  • Patent number: 9593109
    Abstract: The present disclosure relates to compounds that act as agonists of, or otherwise modulate the activity of, GPR131 and to their use in the treatment of various diseases. In particular embodiments, the structure of the compounds is given by Formula I: wherein the variables are as described herein. Related compositions, formulations and methods for the preparation of compounds of formula I are also described.
    Type: Grant
    Filed: August 24, 2012
    Date of Patent: March 14, 2017
    Assignee: CYMABAY THERAPEUTICS, INC.
    Inventors: Jiangao Song, Phuongly Pham, Jingyuan Ma, Aaron Robert Novack, Imad Nashashibi, David W. G. Wone, Dong-Fang Shi, Xin Chen
  • Publication number: 20150239881
    Abstract: Compounds and methods are provided for the treatment of, inter alia, Type II diabetes and other diseases associated with poor glycemic control. The compounds of the invention are orally active.
    Type: Application
    Filed: February 19, 2015
    Publication date: August 27, 2015
    Applicant: CymaBay Therapeutics, Inc.
    Inventors: Xin Chen, Peng Cheng, L. Edward Clemens, Jeffrey D. Johnson, Jingyuan Ma, Alison Murphy, Imad Nashashibi, Christopher J. Rabbat, Jiangao Song, Maria E. Wilson, Yan Zhu, Zuchun Zhao
  • Patent number: 8975258
    Abstract: Compounds and methods are provided for the treatment of, inter alia, Type II diabetes and other diseases associated with poor glycemic control. The compounds of the invention are orally active.
    Type: Grant
    Filed: September 12, 2012
    Date of Patent: March 10, 2015
    Assignee: Cymabay Therapeutics, Inc.
    Inventors: Xin Chen, Peng Cheng, L. Edward Clemens, Jeffrey D. Johnson, Jingyuan Ma, Alison Murphy, Imad Nashashibi, Christopher J. Rabbat, Jiangao Song, Maria E. Wilson, Yan Zhu, Zuchun Zhao
  • Patent number: 8921350
    Abstract: Compounds and methods are provided for the treatment of, inter alia, Type II diabetes and other diseases associated with poor glycemic control. The compounds of the invention are orally active.
    Type: Grant
    Filed: January 16, 2013
    Date of Patent: December 30, 2014
    Assignee: CymaBay Therapeutics, Inc.
    Inventors: Xin Chen, Peng Cheng, L. Edward Clemens, Jeffrey D. Johnson, Jingyuan Ma, Alison Murphy, Imad Nashashibi, Christopher J. Rabbat, Jiangao Song, Maria E. Wilson, Yan Zhu, Zuchun Zhao
  • Patent number: 8846675
    Abstract: Compounds and methods are provided for the treatment of, inter alia, Type II diabetes and other diseases associated with poor glycemic control.
    Type: Grant
    Filed: May 3, 2012
    Date of Patent: September 30, 2014
    Assignee: Cymabay Therapeutics, Inc.
    Inventors: Jingyuan Ma, Christopher J. Rabbat, Jiangao Song, Xin Chen, Imad Nashashibi, Zuchun Zhao, Aaron Novack, Dong Fang Shi, Peng Cheng, Yan Zhu, Alison Murphy
  • Publication number: 20140121246
    Abstract: GPR120 agonists are provided. These compounds are useful for the treatment of metabolic diseases, including Type II diabetes and diseases associated with poor glycemic control.
    Type: Application
    Filed: October 15, 2013
    Publication date: May 1, 2014
    Applicant: Metabolex, Inc.
    Inventors: Dong Fang Shi, Jiangao Song, Christopher J. Rabbat, Jingyuan Ma, Aaron Novack, Imad Nashashibi, Xin Chen