Abstract: The present invention relates to a medical dressing, in particular to a heparin sodium supported hydrogel sustained-release paster. The inventive heparin sodium supported hydrogel sustained-release paster includes a fixing layer and a backing layer and a hydrogel functional layer successively arranged on the fixing layer. The hydrogel functional layer is made up of hydrophilic high-molecular compound, heparin sodium and aqueous transdermal absorbefacient solution to through high-energy ray radiation or freeze-thaw cycle or combination of high-energy ray radiation and freeze-thaw cycle. The invention has the advantages as follows: the flake solid hydrogel material, synthesized by hydrophilic high-molecular compound with high biosecurity, has features of high biosecurity, high moisture content, compact molecular structure, controllable is water loss rate and prolonged service life.