Abstract: The present invention provides a high-purity isothiocyanate compound preparation method for industrial production. Specifically, in the method, organic amine and CS2 are used as raw materials to prepare the thiocarbamate, and then desulfurization is carried out, and the high-purity isothiocyanate compound is obtained by using purification, post-processing and other methods. The method in the present invention is suitable for industrial production, is simple in the post-processing, has a high yield rate, and allows the product to have a high purity, and is suitable for the production of the isothiocyanate compound in the pharmaceutical industry.

Abstract: The disclosure provides a device and method for extracting a clean liquid from a slurry reactor in an environment-friendly and energy-saving manner. The method mainly includes the following steps: S1. siphoning slurry in the slurry reactor into a material collecting pipe, and then spraying the slurry into a settling tank, so that solid particles settle in the settling tank and return to the slurry reactor through a discharging pipe; S2. making supernatant in the settling tank flow upward along a settling pipe, and then flow downward at a pipe intersection into a clear liquid pipe and flow into a clear liquid transition tank; S3. discharging liquid from the clear liquid transition tank in an overflow manner to keep the constant liquid level and a pressure required for siphoning; and S4.

Abstract: Disclosed is the use of isothiocyanate compounds. In particular, disclosed is the use of a compound as shown by Formula (I) or a derivative as shown by Formula (II) in the manufacture of a composition or preparation for preventing and/or treating hyperlipidemia. The compound of the present invention can reduce the levels of triglycerides and low density lipoproteins in the serum of mammals (such as rats and humans), increase the level of high density lipoproteins in the serum, and reduce the level of total bilirubin in the serum of mammals (such as rats and humans).

Abstract: The present invention provides a high-purity isothiocyanate compound preparation method for industrial production. Specifically, in the method, organic amine and CS2 are used as raw materials to prepare the thiocarbamate, and then desulfurization is carried out, and the high-purity isothiocyanate compound is obtained by using purification, post-processing and other methods. The method in the present invention is suitable for industrial production, is simple in the post-processing, has a high yield rate, and allows the product to have a high purity, and is suitable for the production of the isothiocyanate compound in the pharmaceutical industry.

Abstract: Disclosed is the use of isothiocyanate compounds. In particular, disclosed is the use of a compound as shown by Formula (I) or a derivative as shown by Formula (II) in the manufacture of a composition or preparation for preventing and/or treating hyperlipidemia. The compound of the present invention can reduce the levels of triglycerides and low density lipoproteins in the serum of mammals (such as rats and humans), increase the level of high density lipoproteins in the serum, and reduce the level of total bilirubin in the serum of mammals (such as rats and humans).

Abstract: The present invention relates to a combined application of isothiocyanate compounds and anti-cancer drugs, in particular to a composition, comprising: (A) a therapeutically effective amount of a first active ingredient, the first active ingredient being an isothiocyanate compound or derivative thereof; (B) a therapeutically effective amount of a second active ingredient, the second active ingredient being anti-cancer drugs effecting or influencing DNA, kinase inhibitor anti-cancer drugs or endocrine therapy hormonal anti-cancer drugs, the mass ratio of the first active ingredient and the second active ingredient being from 1:10000 to 10000:1. Also disclosed are an active ingredient composition, kit, pharmaceutical composition and uses thereof in the preparation of anti-cancer drugs. The composition, active ingredient composition and kit have excellent effect of inhibiting the growth of cancer cells.

Abstract: The present invention relates to a combined application of isothiocyanate compounds and anti-cancer drugs, in particular to a composition, comprising: (A) a therapeutically effective amount of a first active ingredient, the first active ingredient being an isothiocyanate compound or derivative thereof; (B) a therapeutically effective amount of a second active ingredient, the second active ingredient being anti-cancer drugs effecting or influencing DNA, kinase inhibitor anti-cancer drugs or endocrine therapy hormonal anti-cancer drugs, the mass ratio of the first active ingredient and the second active ingredient being from 1:10000 to 10000:1. Also disclosed are an active ingredient composition, kit, pharmaceutical composition and uses thereof in the preparation of anti-cancer drugs. The composition, active ingredient composition and kit have excellent effect of inhibiting the growth of cancer cells.

Abstract: A micro-mixer and use thereof for synthesis of barium sulfate particles is disclosed. The micro-mixer includes feeding tubes, reservoirs, a mixing channel, a buffer reservoir and a sampling tube. The mixing channel is made of hydrophobic materials and processed into a spiral structure, in which baffles are set in interval arrangement at both sides of the channel wall. The types of the baffles include leaning-forward baffles, vertical baffles and leaning-backward baffles. Setting the baffles helps produce local secondary flow in the mixer, which enhances fluids mixing process. The micro-mixer is suitable to rapid reactions or precipitation processes, whose reaction time is much less than mixing time, and has broad application prospects in many fields involving mixing reaction such as pharmaceutical and chemistry industry.

Abstract: A micro-mixer and use thereof for synthesis of barium sulfate particles is disclosed. The micro-mixer includes feeding tubes, reservoirs, a mixing channel, a buffer reservoir and a sampling tube. The mixing channel is made of hydrophobic materials and processed into a spiral structure, in which baffles are set in interval arrangement at both sides of the channel wall. The types of the baffles include leaning-forward baffles, vertical baffles and leaning-backward baffles. Setting the baffles helps produce local secondary flow in the mixer, which enhances fluids mixing process. The micro-mixer is suitable to rapid reactions or precipitation processes, whose reaction time is much less than mixing time, and has broad application prospects in many fields involving mixing reaction such as pharmaceutical and chemistry industry.

Abstract: A novel class of azaindole-indole coupled derivatives, their preparation methods, pharmaceutical compositions containing the same and the uses thereof. The common structural feature of these derivatives is that they are coupled by azaindole and indole bi-molecule at different positions, forming extended pi-conjugated systems. Such derivatives inhibited cell growth and proliferation by various mechanisms. The present compounds have improved solubility, increased bioavailability, and thus have enhanced drug actions, and reduced medical dosages and undesired responses.

Abstract: A method for preventing and treating prostatic diseases and skin cancer using naturally or artificially synthesized isothiocyanates compounds or the derivatives or metabolites thereof.

Abstract: A method for preventing and treating prostatic diseases and skin cancer using naturally or artificially synthesized isothiocyanates compounds or the derivatives or metabolites thereof.

Abstract: A method for preventing and treating prostatic diseases and skin cancer using naturally or artificially synthesized isothiocyanates compounds or the derivatives or metabolites thereof.

Abstract: A novel class of azaindole-indole coupled derivatives, their preparation methods, pharmaceutical compositions containing the same and the uses thereof. The common structural feature of these derivatives is that they are coupled by azaindole and indole bi-molecule at different positions, forming extended pi-conjugated systems. Such derivatives inhibited cell growth and proliferation by various mechanisms. The present compounds have improved solubility, increased bioavailability, and thus have enhanced drug actions, and reduced medical dosages and undesired responses.

Abstract: A method for preventing and treating prostatic diseases and skin cancer using naturally or artificially synthesized isothiocyanates compounds or the derivatives or metabolites thereof.