Abstract: Provided is use of serine/arginine splicing factor 1 (SRSF1) in preparation of a medicament for prophylaxis and/or treatment of heart failure with preserved ejection fraction (HFpEF), which belongs to the field of biomedical technology. The SRSF1 is identified as a key target for preparing a medicament for the prophylaxis and/or treatment of HFpEF. Animal modeling and cellular level experiment has demonstrated that SRSF1 is involved in regulation of the pathological process of the disease. In vivo modeling experiment in SRSF1 endothelial cell-specific knockout mice indicates that inhibiting SRSF1 expression improves symptoms such as diastolic dysfunction and hypertension, alleviates pulmonary edema, and inhibits myocardial fibrosis and remodeling. Moreover, suppressing SRSF1 expression improves abnormal glucose/lipid metabolism and inhibits the endothelial-to-mesenchymal transition process.

Abstract: In an action processing method, a robot is controlled to move to an action region of an individual on a first support structure. According to a first motion sequence, a manipulator assembly of the robot is controlled to adjust the individual from a supine posture on the first support structure to a lateral recumbent posture on the first support structure. The manipulator assembly includes a first manipulator and a second manipulator. According to a second motion sequence, the manipulator assembly is controlled to adjust the individual from the lateral recumbent posture to an upright seated posture on the first support structure. According to a third motion sequence, the manipulator assembly is controlled to transfer the individual from the upright seated posture on the first support structure to an upright seated posture on a second support structure.

Abstract: A method for controlling a wheel-legged robot includes controlling, under a first constraint of a support region corresponding to an initial posture, through a first outer mechanical leg and at least one inner mechanical leg, the wheel-legged robot to stand on a first support surface, wherein the support region is enclosed by contact points between foot wheels of mechanical legs of the wheel-legged robot and the first support surface; and controlling a first contact point between a first foot wheel on the first outer mechanical leg and the first support surface to move in a first direction, and controlling a second contact point between a second foot wheel on the at least one inner mechanical leg and the first support surface to move in a second direction, to cause the wheel-legged robot to be switched from the initial posture to a predicted posture.

Abstract: A mobile robot includes at least three swing legs distributed side by side that are grouped into a first swing leg group and a second swing leg group, and at least one from among the first swing leg group and the second swing leg group include at least two swing legs respectively located on two sides of a center of gravity of the mobile robot.

Abstract: A method for controlling a mobile robot includes controlling the mobile robot to be in an initial standing state; and controlling the mobile robot to transform from the initial standing state to a folded state, wherein at least one from among a first swinging leg set of the mobile robot and a second swinging leg set of the mobile robot are horizontally closed together, wherein at least one of the first swinging leg set and the second swinging leg set includes swinging legs, wherein the first swinging leg set and the second swinging leg set are arranged side by side, and wherein a first rotation axis of the first swinging leg set and a second rotation axis of the second swinging leg set are located on a same vertical plane.

Abstract: A robot hip joint apparatus, method, and control apparatus providing enhanced mobility and control. The robot hip joint includes a support assembly, a drive assembly comprising first, second, and third drivers, and an execution assembly comprising first and second movable leg members and a movable waist member. The first and second movable leg members are separately and rotatably connected to the support assembly, with the first and second drivers configured to drive their respective leg members to rotate around a first axis. The method and control apparatus determine a motion mode of the robot hip joint, generate a control signal based on the motion mode, and transmit the control signal to the drive assembly to control the movement of the leg and waist members for coordinated robotic motion.

Abstract: A method, apparatus, and computer-readable storage medium for controlling a mobile robot, performed by a controller of the mobile robot, and the method comprising: controlling a first swing leg group to be located on a first stair or a first support surface, and controlling a second swing leg group to be located on a second stair; controlling the first swing leg group to swing to a third stair with the second swing leg group as a support leg; and controlling the second swing leg group to swing to a fourth stair with the first swing leg group as a support leg; wherein the first swing leg group and the second swing leg group comprise rotation shafts and a plurality of swing legs; wherein the first swing leg group and the second swing leg group are distributed side by side; and wherein the rotation shaft of the first swing leg group and the rotation shaft of the second swing leg group are located in the same vertical plane.

Abstract: A mechanical arm includes a first link connectable to a surface, a second link, a third link, a fourth link, and a fifth link that are coupled to one another in series, and an end effector connectable to the fifth link. The end effector is rotatable about an axis of rotation same as an axis of rotation of the fourth link, and rotatable about an axis of rotation orthogonal to the axis of rotation of the fourth link. The first link, the second link, the third link, the fourth link, and the fifth link are collectively structured and configured to rotate such that the end effector is actuatable to a workspace under the surface.

Abstract: A mechanical arm includes a first link connectable to a surface, a second link, a third link, a fourth link, and a fifth link that are coupled to one another in series, and an end effector connectable to the fifth link. The end effector is rotatable about an axis of rotation same as an axis of rotation of the fourth link, and rotatable about an axis of rotation orthogonal to the axis of rotation of the fourth link. The first link, the second link, the third link, the fourth link, and the fifth link are collectively structured and configured to rotate such that the end effector is actuatable to a workspace under the surface.