Patents by Inventor Jingen LI

Jingen LI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • A RECOMBINANT FILAMENTOUS FUNGUS FOR PRODUCING ETHANOL AND ITS CONSTRUCTION AND APPLICATION
    Publication number: 20230053729
    Abstract: The invention discloses a construction method of genetic engineering fungi of filamentous fungi. Through the genetic engineering method, the filamentous fungi overexpress the positive regulation genes of ethanol synthesis, and/or down regulate the negative regulation genes of endogenous ethanol synthesis to obtain genetic engineering strains. Or overexpression of acetaldehyde dehydrogenase and ethanol dehydrogenase containing mitochondrial localization signal sequence, or overexpression of pyruvate decarboxylase and ethanol dehydrogenase containing mitochondrial localization signal sequence, or overexpression of acetaldehyde dehydrogenase, ethanol dehydrogenase and pyruvate decarboxylase containing mitochondrial localization signal sequence in filamentous fungal cells. Compared with the original strain, the ethanol synthesis ability of the obtained genetically engineered strains are improved.
    Type: Application
    Filed: December 9, 2020
    Publication date: February 23, 2023
    Inventors: Chaoguang TIAN, Yongli ZHANG, Jingen LI, Tao SUN, Qian LIU, Wenliang SUN
  • Dibasic organic acid producing strain and preparation and application of same
    Patent number: 11390890
    Abstract: Provided are an engineered strain for synthesizing a dibasic organic acid and preparation and application of same. The engineered strain introduces or up-regulates expression of a positive regulator gene for synthesis of a dibasic organic acid, and/or down-regulates expression of a negative regulator gene for synthesis of a dibasic organic acid, as compared with the origin strain of the engineered strain, the producing capability for producing the dibasic organic acid is improved.
    Type: Grant
    Filed: July 20, 2020
    Date of Patent: July 19, 2022
    Assignee: TIANJIN INSTITUTE OF INDUSTRIAL BIOTECHNOLOGY, CHINESE ACADEMY OF SCIENCES
    Inventors: Chaoguang Tian, Jingen Li, Chuannan Long, Tao Sun, Liangcai Lin, Jing Xu, Qian Liu, Jingxiao Ji, Wenliang Sun, Yanhe Ma
  • NEW MUTANT PROTEIN FOR IMPROVING MALIC ACID YIELD
    Publication number: 20210371844
    Abstract: The present invention provides a class of new mutant proteins for increasing malic acid yield. Specifically, the present invention provides a class of new pyruvate carboxylase mutant protein and malic acid transporter mutant proteins or combinations thereof, a preparation method therefor and use thereof in improving malic acid yield.
    Type: Application
    Filed: October 18, 2019
    Publication date: December 2, 2021
    Applicant: TIANJIN INSTITUTE OF INDUSTRIAL BIOTECHNOLOGY, CHINESE ACADEMY OF SCIENCES
    Inventors: Chaoguang TIAN, Junqi ZHAO, Jingen LI, Lu ZHANG
  • DIBASIC ORGANIC ACID PRODUCING STRAIN AND PREPARATION AND APPLICATION OF SAME
    Publication number: 20200347415
    Abstract: Provided are an engineered strain for synthesizing a dibasic organic acid and preparation and application of same. The engineered strain introduces or up-regulates expression of a positive regulator gene for synthesis of a dibasic organic acid, and/or down-regulates expression of a negative regulator gene for synthesis of a dibasic organic acid, as compared with the origin strain of the engineered strain, the producing capability for producing the dibasic organic acid is improved.
    Type: Application
    Filed: July 20, 2020
    Publication date: November 5, 2020
    Inventors: Chaoguang TIAN, Jingen LI, Chuannan LONG, Tao SUN, Liangcai LIN, Jing XU, Qian LIU, Jingxiao JI, Wenliang SUN, Yanhe MA
  • Dibasic organic acid producing strain and preparation and application of same
    Patent number: 10781462
    Abstract: Provided are an engineered strain for synthesizing a dibasic organic acid and preparation and application of same. The engineered strain introduces or up-regulates expression of a positive regulator gene for synthesis of a dibasic organic acid, and/or down-regulates expression of a negative regulator gene for synthesis of a dibasic organic acid, as compared with the origin strain of the engineered strain, the producing capability for producing the dibasic organic acid is improved.
    Type: Grant
    Filed: February 4, 2016
    Date of Patent: September 22, 2020
    Assignee: TIANJIN INSTITUTE OF INDUSTRIAL BIOTECHNOLOGY, CHINESE ACADEMY OF SCIENCES
    Inventors: Chaoguang Tian, Jingen Li, Chuannan Long, Tao Sun, Liangcai Lin, Jing Xu, Qian Liu, Jingxiao Ji, Wenliang Sun, Yanhe Ma
  • DIBASIC ORGANIC ACID PRODUCING STRAIN AND PREPARATION AND APPLICATION OF SAME
    Publication number: 20180171369
    Abstract: Provided are an engineered strain for synthesizing a dibasic organic acid and preparation and application of same. The engineered strain introduces or up-regulates expression of a positive regulator gene for synthesis of a dibasic organic acid, and/or down-regulates expression of a negative regulator gene for synthesis of a dibasic organic acid, as compared with the origin strain of the engineered strain, the producing capability for producing the dibasic organic acid is improved.
    Type: Application
    Filed: February 4, 2016
    Publication date: June 21, 2018
    Inventors: Chaoguang TIAN, Jingen LI, Chuannan LONG, Tao SUN, Liangcai LIN, Jing XU, Qian LIU, Jingxiao JI, Wenliang SUN, Yanhe MA