Patents by Inventor Jinghong WAN

Jinghong WAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11504730
    Abstract: Disclosed is a method for calculating instantaneous sprinkler strength comprising: ensuring that a translational sprinkler (1) maintains a stable operating state, placing b rain barrels (3) at a distance of a metres from the translational sprinkler (1), and moving the translational sprinkler (1) to obtain measurement data; calculating movement time, and the average sprayed water depth received by the rain barrels (3); assuming the distribution form of the amount of water of the translational sprinkler (1), establishing a function relationship between an instantaneous sprinkler strength ht and the movement time t, and calculating a variable in the function relationship; and substituting into the established function relationship a specific numerical value of an instantaneous point in time t of the movement of the translational sprinkler (1), so that the value of ht obtained is a numerical value of the instantaneous sprinkler strength of the translational sprinkler (1).
    Type: Grant
    Filed: November 22, 2016
    Date of Patent: November 22, 2022
    Assignee: Jiangsu University
    Inventors: Xingye Zhu, Junping Liu, Shouqi Yuan, Kun Tian, Jinghong Wan
  • Publication number: 20220081481
    Abstract: Sustained hepatic and systemic inflammation, in particular originating from monocyte/macrophages, is a driving force for chronic liver disease progression to cirrhosis and underlies the development of multiorgan failure. Therefore, reprogramming mono-cyte/macrophage phenotype has emerged as an interesting strategy to limit inflammation during chronic liver injury. The inventors report here that a non-canonical form of autophagy, LC3-associated phagocytosis (LAP), is endogenously enhanced in blood and liver monocytes from cirrhotic patients and is negatively correlated to the levels of inflammatory markers in these patients. Pharmacological inhibition of LAP components or genetic disruption of LAP (Rubicon-deficient mice in myeloid cells), exacerbates the inflammatory signature in isolated human cirrhotic monocytes and the hepatic inflammatory profile in mice with chronic liver injury, resulting in enhanced liver fibrosis.
    Type: Application
    Filed: January 15, 2020
    Publication date: March 17, 2022
    Inventors: Sophie LOTERSZTAJN, Jinghong WAN, Patrice CODOGNO, Sanae BEN MKADDEM, Renato MONTEIRO, Loredana SAVEANU, Emmanuel WEISS
  • Publication number: 20210403573
    Abstract: Persistent inflammation is a driving force of fibrosis progression. Mucosal-Associated Invariant T (MAIT) cells are non-conventional T cells that display altered functions during chronic inflammatory diseases. Here, the inventors report a loss of circulating MAIT cells in cirrhotic patients and their hepatic accumulation in an activated phenotype within the fibrotic septa. Using two models of chronic liver injury, the inventors demonstrate that mice enriched in MAIT cells (V?19TCRTg) show exacerbated liver fibrosis and higher number of hepatic fibrogenic cells than wild type counterparts, whereas MAIT cell-deficient mice (MR1?/?mice) are resistant. The results highlight the profibrogenic functions of MAIT cells and suggest that 1 targeting MAIT cells may constitute an attractive antifibrogenic strategy during chronic liver injury.
    Type: Application
    Filed: June 22, 2017
    Publication date: December 30, 2021
    Inventors: Sophie LOTERSZTAJN, JingHong WAN, Valérie PARADIS, Agnès LEHUEN, Pushpa HEGDE, Emmanuel WEISS
  • Patent number: 11140839
    Abstract: Disclosed is a method for calculating the depth of sprayed water of a translational sprinkler in different working conditions, involving placing rain barrels (3) in n rows in the movement direction of a translational sprinkler (1), each row having m barrels, such that the spray radius of rain droplets can completely cover the rain barrels (3) while ensuring that the translational sprinkler (1) is spraying stably; calculating the average sprinkler strength of each rain barrel (3); drawing a relationship curve of the sprinkler strength and the distance from the centre; setting the movement speed s of the translational sprinkler (1); establishing a function relationship between a sprinkler strength d? and time t; calculating the time t2 needed for the translational sprinkler (1) to completely pass one of the rain barrels (3); and with the condition that the movement time is t2, performing mathematical integration on the sprinkler strength function to obtain the sprinkled depth of water at a certain rain barrel (
    Type: Grant
    Filed: November 22, 2016
    Date of Patent: October 12, 2021
    Assignee: Jiangsu University
    Inventors: Xingye Zhu, Shouqi Yuan, Junping Liu, Jinghong Wan, Kun Tian
  • Publication number: 20200047205
    Abstract: Disclosed is a method for calculating instantaneous sprinkler strength comprising: ensuring that a translational sprinkler (1) maintains a stable operating state, placing b rain barrels (3) at a distance of a metres from the translational sprinkler (1), and moving the translational sprinkler (1) to obtain measurement data; calculating movement time, and the average sprayed water depth received by the rain barrels (3); assuming the distribution form of the amount of water of the translational sprinkler (1), establishing a function relationship between an instantaneous sprinkler strength ht and the movement time t, and calculating a variable in the function relationship; and substituting into the established function relationship a specific numerical value of an instantaneous point in time t of the movement of the translational sprinkler (1), so that the value of ht obtained is a numerical value of the instantaneous sprinkler strength of the translational sprinkler (1).
    Type: Application
    Filed: November 22, 2016
    Publication date: February 13, 2020
    Inventors: Xingye ZHU, Jungping LIU, Shouqi YUAN, Kun TIAN, Jinghong WAN
  • Publication number: 20190269077
    Abstract: Disclosed is a method for calculating the depth of sprayed water of a translational sprinkler in different working conditions, involving placing rain barrels (3) in n rows in the movement direction of a translational sprinkler (1), each row having m barrels, such that the spray radius of rain droplets can completely cover the rain barrels (3) while ensuring that the translational sprinkler (1) is spraying stably; calculating the average sprinkler strength of each rain barrel (3); drawing a relationship curve of the sprinkler strength and the distance from the centre; setting the movement speed s of the translational sprinkler (1); establishing a function relationship between a sprinkler strength d? and time t; calculating the time t2 needed for the translational sprinkler (1) to completely pass one of the rain barrels (3); and with the condition that the movement time is t2, performing mathematical integration on the sprinkler strength function to obtain the sprinkled depth of water at a certain rain barrel (
    Type: Application
    Filed: November 22, 2016
    Publication date: September 5, 2019
    Inventors: Xingye ZHU, Shouqi YUAN, Junping LIU, Jinghong WAN, Kun TIAN
  • Patent number: 10375905
    Abstract: A detachable frame of a light-small sprinkling machine includes angle steel pieces, tiepieces, support bars, support upright rods, top rod with slots, and wheels. The components of the frame are connected through threaded connections, so that the frame can be disassembled and removed easily. The distance between sprinkler heads and the mounting height of the sprinkler heads may be changed by means of free movement of turning hooks in the top rod with slots. The number of spans of the rod of the machine are be selected according to the topographic structure and can be changed by means of threaded holes in the two ends of the top rod with slots, and thereby the length of the rod can be changed. Employing low-pressure sprinkler heads and utilizing the turning effect of movable swivel shafts, the irrigation sprinkling machine can be turned to any direction freely.
    Type: Grant
    Filed: March 16, 2016
    Date of Patent: August 13, 2019
    Assignee: Jiangsu University
    Inventors: Xingye Zhu, Shouqi Yuan, Junping Liu, Kun Tian, Jinghong Wan, Ya Bao, Xingfa Liu
  • Publication number: 20180352758
    Abstract: A detachable frame of a light-small sprinkling machine for precise irrigation, which belongs to a key equipment in modern agricultural irrigation. The detachable frame of a light-small sprinkling machine for precise irrigation comprises angle steel pieces, tiepieces, support bars, support upright rods, top truss with slots, and wheels, wherein, the components of the frame are connected through threaded connections, so that the frame can be disassembled and removed easily. The distance between sprinkler heads and the mounting height of the sprinkler heads may be changed by means of free movement of turning hooks in the top truss with slots. The number of spans of the truss of the machine can be selected according to the topographic structure and can be changed by means of threaded holes in the two ends of the top truss with slots, and thereby the length of the truss can be changed. The irrigation sprinkling machine has high adaptability, and achieves even sprinkling distribution.
    Type: Application
    Filed: March 16, 2016
    Publication date: December 13, 2018
    Inventors: Xingye ZHU, Shouqi YUAN, Junping LIU, Kun TIAN, Jinghong WAN, Ya BAO, Xingfa LIU