Patents by Inventor Jinghua Pang

Jinghua Pang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11684591
    Abstract: An application of a GABAA receptor allosteric enhancer in medicine.
    Type: Grant
    Filed: July 10, 2019
    Date of Patent: June 27, 2023
    Assignee: XI'AN LIBANG ZHAOXIN BIOTECHNOLOGY CO., LTD
    Inventors: Rutao Wang, Long An, Yi Zhao, Jinghua Pang, Tao Chen, Weijiao Wang
  • Publication number: 20220023219
    Abstract: The disclosure provides a lyophilized preparation of prostaglandin E1 methyl ester for injection and production and use thereof. The lyophilized preparation comprises the following components by weight: 0.1-10 parts of prostaglandin E1 methyl ester, 500-4000 parts of an oil for injection, 500-2000 parts of an emulsifier, 0-10 parts of a co-emulsifier, 5000-50000 parts of a lyoprotectant, and 200-1500 parts of glycerin. The prostaglandin E1 methyl ester lyophilized agent of the disclosure has less blood vessel irritation, good drug stability, and superior drug activity and therapeutic effect than similar prostaglandin E1 products.
    Type: Application
    Filed: October 28, 2019
    Publication date: January 27, 2022
    Inventors: Rutao WANG, Long AN, Yi ZHAO, Jinghua PANG, Tao CHEN
  • Publication number: 20220008437
    Abstract: The disclosure provides use of prostaglandin E1 methyl ester in the manufacture of a vasodilator. The prostaglandin E1 methyl ester has a structure represented by formula (I). the vasodilator is a drug for the treatment of microcirculation disorder, coronary heart disease, angina pectoris, heart failure, pulmonary heart disease, cerebral infarction, amniotic fluid embolism, or scleroderma.
    Type: Application
    Filed: October 28, 2019
    Publication date: January 13, 2022
    Inventors: Rutao WANG, Long AN, Yi ZHAO, Jinghua PANG, Tao CHEN
  • Publication number: 20210315835
    Abstract: An application of a GABAA receptor allosteric enhancer in medicine.
    Type: Application
    Filed: July 10, 2019
    Publication date: October 14, 2021
    Inventors: Rutao WANG, Long AN, Yi ZHAO, Jinghua PANG, Tao CHEN, Weijiao WANG
  • Publication number: 20210315836
    Abstract: The present disclosure provides an allosteric enhancing compound of GABAA receptors or a prodrug thereof, a method for preparing the same, and use thereof. The compound is represented by formula (1), wherein R1 and R2 are each independently selected from isopropyl or n-propyl; and when R1 is n-propyl, R2 is not isopropyl.
    Type: Application
    Filed: July 10, 2019
    Publication date: October 14, 2021
    Inventors: Rutao WANG, Long AN, Yi ZHAO, Jinghua PANG, Tao CHEN, Weijiao WANG
  • Publication number: 20200179302
    Abstract: The present invention relates to use of biphenols in the preparation of a medicament for the prevention and treatment of ischemic stroke, specifically to use of 3,3?,5,5?-tetraisopropyl-4,4?-biphenol and salt, ester, or solvate thereof in the preparation of a medicament for the prevention and treatment of ischemic stroke injury.
    Type: Application
    Filed: February 13, 2020
    Publication date: June 11, 2020
    Inventors: Rutao Wang, Tao Chen, Long An, Yi Zhao, Weijiao Wang, Shupan Guo, Sa Xiao, Jinghua Pang, Huijing Hu
  • Patent number: 10329243
    Abstract: The present invention relates to a biphenyl derivative and use thereof, and the biphenyl derivative has a structure represented by the formula (I) as defined in the specification. The use refers the use of the biphenyl derivative or a pharmaceutically acceptable salt or solvate thereof, or a pharmaceutical composition comprising the biphenyl derivative or a pharmaceutically acceptable salt or solvate thereof in the preparation of a medicament for the treatment and/or prevention of ischemic stroke.
    Type: Grant
    Filed: March 11, 2016
    Date of Patent: June 25, 2019
    Assignee: XI'AN LIBANG PHARMACEUTICAL CO., LTD
    Inventors: Rutao Wang, Tao Chen, Long An, Yi Zhao, Weijiao Wang, Shupan Guo, Sa Xiao, Jinghua Pang, Huijing Hu
  • Publication number: 20180185299
    Abstract: The present invention relates to use of biphenols in the preparation of a medicament for the prevention and treatment of ischemic stroke, specifically to use of 3,3?,5,5?-tetraisopropyl-4,4?-biphenol and salt, ester, or solvate thereof in the preparation of a medicament for the prevention and treatment of ischemic stroke injury.
    Type: Application
    Filed: March 11, 2016
    Publication date: July 5, 2018
    Inventors: Rutao Wang, Tao Chen, Long An, Yi Zhao, Weijiao Wang, Shupan Guo, Sa Xiao, Jinghua Pang, Huijing Hu
  • Publication number: 20180141895
    Abstract: The present invention relates to a biphenyl derivative and use thereof, and the biphenyl derivative has a structure represented by the formula (I) as defined in the specification. The use refers the use of the biphenyl derivative or a pharmaceutically acceptable salt or solvate thereof, or a pharmaceutical composition comprising the biphenyl derivative or a pharmaceutically acceptable salt or solvate thereof in the preparation of a medicament for the treatment and/or prevention of ischemic stroke.
    Type: Application
    Filed: March 11, 2016
    Publication date: May 24, 2018
    Inventors: Rutao Wang, Tao Chen, Long An, Yi Zhao, Weijiao Wang, Shupan Guo, Sa Xiao, Jinghua Pang, Huijing Hu