Patents by Inventor Jingjuan Qiao

Jingjuan Qiao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TARGETED PROTEIN CONTRAST AGENTS, METHODS OF MAKING, AND USES THEREOF
    Publication number: 20230057249
    Abstract: Provided herein are protein contrast agents and targeted protein contrast agents, formulations thereof, and methods of use, including but not limited to, as a magnetic resonance imaging contrast agent.
    Type: Application
    Filed: August 11, 2022
    Publication date: February 23, 2023
    Inventors: Jenny Jie Yang, Fan Pu, Shenghui Xue, Jingjuan Qiao, Shanshan Tan, Mani Salarian
  • Targeted protein contrast agents, methods of making, and uses thereof
    Patent number: 11426471
    Abstract: Provided herein are protein contrast agents and targeted protein contrast agents, formulations thereof, and methods of use, including but not limited to, as a magnetic resonance imaging contrast agent.
    Type: Grant
    Filed: September 9, 2020
    Date of Patent: August 30, 2022
    Assignee: Georgia State University Research Foundation, Inc.
    Inventors: Jenny Jie Yang, Fan Pu, Shenghui Xue, Jingjuan Qiao, Shanshan Tan, Mani Salarian
  • Targeted protein contrast agents, methods of making, and uses thereof
    Patent number: 11419954
    Abstract: Provided herein are protein contrast agents and targeted protein contrast agents, formulations thereof, and methods of use, including but not limited to, as a magnetic resonance imaging contrast agent.
    Type: Grant
    Filed: September 9, 2020
    Date of Patent: August 23, 2022
    Assignee: Georgia State University Research Foundation, Inc.
    Inventors: Jenny Jie Yang, Fan Pu, Shenghui Xue, Jingjuan Qiao, Shanshan Tan, Mani Salarian
  • TARGETED PROTEIN CONTRAST AGENTS, METHODS OF MAKING, AND USES THEREOF
    Publication number: 20210038746
    Abstract: Provided herein are protein contrast agents and targeted protein contrast agents, formulations thereof, and methods of use, including but not limited to, as a magnetic resonance imaging contrast agent.
    Type: Application
    Filed: September 9, 2020
    Publication date: February 11, 2021
    Inventors: Jenny Jie YANG, Fan PU, Shenghui XUE, Jingjuan QIAO, Shanshan TAN, Mani SALARIAN
  • TARGETED PROTEIN CONTRAST AGENTS, METHODS OF MAKING, AND USES THEREOF
    Publication number: 20200397925
    Abstract: Provided herein are protein contrast agents and targeted protein contrast agents, formulations thereof, and methods of use, including but not limited to, as a magnetic resonance imaging contrast agent.
    Type: Application
    Filed: September 9, 2020
    Publication date: December 24, 2020
    Inventors: Jenny Jie YANG, Fan PU, Shenghui XUE, Jingjuan QIAO, Shanshan TAN, Mani SALARIAN
  • Targeted protein contrast agents, methods of making, and uses thereof
    Patent number: 10814020
    Abstract: Provided herein are protein contrast agents and targeted protein contrast agents, formulations thereof, and methods of use, including but not limited to, as a magnetic resonance imaging contrast agent.
    Type: Grant
    Filed: May 11, 2016
    Date of Patent: October 27, 2020
    Assignee: GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
    Inventors: Jenny Jie Yang, Fan Pu, Shenghui Xue, Jingjuan Qiao, Mani Salarian, Shanshan Tan
  • TARGETED PROTEIN CONTRAST AGENTS, METHODS OF MAKING, AND USES THEREOF
    Publication number: 20180280544
    Abstract: Provided herein are protein contrast agents and targeted protein contrast agents, formulations thereof, and methods of use, including but not limited to, as a magnetic resonance imaging contrast agent.
    Type: Application
    Filed: May 11, 2016
    Publication date: October 4, 2018
    Inventors: Jenny Jie YANG, Fan PU, Shenguhi XUE, Jingjuan QIAO, Mani SALARIAN
  • Contrast agents, methods for preparing contrast agents, and methods of imaging
    Patent number: 9956304
    Abstract: Provided is a protein contrast agent for enhancing an MRI image and comprising a polypeptide having a conformation presenting at least five oxygen atoms positioned to chelate at least one paramagnetic metal ion such as Gd3+, each oxygen atom being between about 2 angstrom units and about 5 angstrom units from the metal ion; the metal ion has at least one water molecule electrostatically interacting a distance of less than about 10 angstrom units a target-specific moiety conjugated thereto, at least one polyethylene glycol molecule, and a paramagnetic metal ion. Also provided is a method of obtaining an enhanced MRI image using the protein contrast agent to a T2/T1 or T1/T2 intensity ratio of the MRI image; and (d) obtaining an image of the T2/T1 or T1/T2 intensity ratio.
    Type: Grant
    Filed: June 5, 2013
    Date of Patent: May 1, 2018
    Assignee: Georgia State University Research Foundation, Inc.
    Inventors: Jenny Jie Yang, Zhiren Liu, Shunyi Li, Yubin Zhou, Jie Jiang, Shenghui Xue, Jingjuan Qiao, Lixia Wei
  • CONTRAST AGENTS, METHODS FOR PREPARING CONTRAST AGENTS, AND METHODS OF IMAGING
    Publication number: 20150202330
    Abstract: Provided is a protein contrast agent for enhancing an MRI image and comprising a polypeptide having a conformation presenting at least five oxygen atoms positioned to chelate at least one paramagnetic metal ion such as Gd3+, each oxygen atom being between about 2 angstrom units and about 5 angstrom units from the metal ion; the metal ion has at least one water molecule electrostatically interacting a distance of less than about 10 angstrom units a target-specific moiety conjugated thereto, at least one polyethylene glycol molecule, and a paramagnetic metal ion. Also provided is a method of obtaining an enhanced MRI image using the protein contrast agent to a T2/T1 or T1/T2 intensity ratio of the MRI image; and (d) obtaining an image of the T2/T1 or T1/T2 intensity ratio.
    Type: Application
    Filed: June 5, 2013
    Publication date: July 23, 2015
    Inventors: Jenny Jie Yang, Zhiren Liu, Shunyi Li, Yubin Zhou, Jie Jiang, Shenghui Xue, Jingjuan Qiao, Lixia Wei