Patents by Inventor Jingliang JU

Jingliang JU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9074246
    Abstract: The application relates generally to methods useful for the selective amplification of one or more target nucleic acid or fragments thereof, as well as compositions and kits comprising said amplification reaction mixtures. More specifically, the application relates to a composite primer that comprises a 5? promoter portion and a 3? target-recognition portion which is complementary to the 3? end portion of a target polynucleotide sequence; and optionally, a means for identifying the 5? end portion of the target polynucleotide sequence. The amplification reaction mixture comprises at least one handle-stem-loop structure which comprises a 5? single-stranded handle comprising the promoter portion and a double-stranded stem comprising at least one pair of self-folding segments hybridized to each other, and optionally, a single-stranded loop comprising the sequence between the pair of self-folding segments.
    Type: Grant
    Filed: January 25, 2011
    Date of Patent: July 7, 2015
    Assignee: RD Biosciences, Inc.
    Inventor: Jingliang Ju
  • Publication number: 20130040344
    Abstract: The application relates generally to methods useful for the selective amplification of one or more target nucleic acid or fragments thereof, as well as compositions and kits comprising said amplification reaction mixtures. More specifically, the application relates to a composite primer that comprises a 5? promoter portion and a 3? target-recognition portion which is complementary to the 3? end portion of a target polynucleotide sequence; and optionally, a means for identifying the 5? end portion of the target polynucleotide sequence. The amplification reaction mixture comprises at least one handle-stem-loop structure which comprises a 5? single-stranded handle comprising the promoter portion and a double-stranded stem comprising at least one pair of self-folding segments hybridized to each other, and optionally, a single-stranded loop comprising the sequence between the pair of self-folding segments.
    Type: Application
    Filed: January 25, 2011
    Publication date: February 14, 2013
    Inventor: Jingliang Ju
  • Publication number: 20100092963
    Abstract: The application relates generally to kits and methods useful for the selective capture, amplification and/or detection of one or more nucleic acid targets, as well as compositions comprising said amplification reaction mixtures. More specifically, the application relates to a signal primer that comprises (i) a target-specific sequence which hybridizes specifically to a nucleic acid target, and (ii) a signal sequence upstream of the target-specific sequence, wherein the signal sequence is preferably not found in the nucleic acid target or its complementary sequence; and a detection means for detecting the presence of the complementary sequence of the signal sequence in amplified nucleic acid target products.
    Type: Application
    Filed: June 15, 2009
    Publication date: April 15, 2010
    Inventor: Jingliang JU