Patents by Inventor Jinglin Fu

Jinglin Fu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DNA logic-gated proximity assembly circuit for biochemical sensing
    Patent number: 10961565
    Abstract: Provided are nucleic acid-based sensors, kits that include such sensors, and methods for making and using such sensors. The sensors permit detection of a broad array of target agents, such as nucleic acids (e.g., DNA and RNA), proteins, cells, and small molecules (e.g., toxins and metals). In some examples, the sensors determine the activity of a protein, such as an enzyme's activity. The assays provide easy-to-read signals for point-of-care diagnosis. The sensors control the conformational switch for recognizing targets and to trigger the subsequent assembly of enzyme/cofactor structures for producing and amplifying signals.
    Type: Grant
    Filed: March 22, 2019
    Date of Patent: March 30, 2021
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Jinglin Fu, Sung Won Oh, Adriana Rosa Pereira
  • NANOCAGED ENZYMES WITH ENHANCED CATALYTIC ACTIVITY AND INCREASED STABILITY
    Publication number: 20200270599
    Abstract: The present disclosure describes a nanoparticle comprising a three dimensional DNA nanocage and a payload biological macromolecule, and methods of assembly thereof.
    Type: Application
    Filed: March 6, 2020
    Publication date: August 27, 2020
    Inventors: Jinglin FU, Zhao ZHAO, Neal WOODBURY, Hao YAN
  • Nanocaged enzymes with enhanced catalytic activity and increased stability
    Patent number: 10669534
    Abstract: The present disclosure describes a nanoparticle comprising a three dimensional DNA nanocage and a payload biological macromolecule, and methods of assembly thereof.
    Type: Grant
    Filed: July 13, 2017
    Date of Patent: June 2, 2020
    Assignee: Arizona Board of Regents on behalf of Arizona State University
    Inventors: Jinglin Fu, Zhao Zhao, Neal Woodbury, Hao Yan
  • DNA LOGIC-GATED PROXIMITY ASSEMBLY CIRCUIT FOR BIOCHEMICAL SENSING
    Publication number: 20190292580
    Abstract: Provided are nucleic acid-based sensors, kits that include such sensors, and methods for making and using such sensors. The sensors permit detection of a broad array of target agents, such as nucleic acids (e.g., DNA and RNA), proteins, cells, and small molecules (e.g., toxins and metals). In some examples, the sensors determine the activity of a protein, such as an enzyme's activity. The assays provide easy-to-read signals for point-of-care diagnosis. The sensors control the conformational switch for recognizing targets and to trigger the subsequent assembly of enzyme/cofactor structures for producing and amplifying signals.
    Type: Application
    Filed: March 22, 2019
    Publication date: September 26, 2019
    Applicant: Rutgers, The State University of New Jersey
    Inventors: Jinglin Fu, Sung Won Oh, Adriana Rosa Pereira
  • Nanocaged Enzymes with Enhanced Catalytic Activity and Increased Stability
    Publication number: 20180016569
    Abstract: The present disclosure describes a nanoparticle comprising a three dimensional DNA nanocage and a payload biological macromolecule, and methods of assembly thereof.
    Type: Application
    Filed: July 13, 2017
    Publication date: January 18, 2018
    Inventors: Jinglin Fu, Zhao Zhao, Neal Woodbury, Hao Yan
  • SELECTING FOR COOPERATIVELY INTERACTING MOLECULES
    Publication number: 20120094271
    Abstract: The present invention provides method of identifying molecules that cooperatively and positively interact with either a ligand or a target molecule of a ligand/target molecule pair, or molecules that interact with a ligand/target molecule complex.
    Type: Application
    Filed: August 17, 2009
    Publication date: April 19, 2012
    Applicant: Arizona Board of Regents for and on behalf of Arizona State University
    Inventors: Jinglin Fu, Neal W. Woodbury, Stephen Albert Johnston