Patents by Inventor Jinglu WANG

Jinglu WANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cyclic dinucleotide analogue, pharmaceutical composition thereof, and application
    Patent number: 12152051
    Abstract: A cyclic dinucleotide analogue, a pharmaceutical composition thereof, and application. A cyclic dinucleotide analogue (I), an isomer thereof, a prodrug, a stable isotope derivative, or a pharmaceutically acceptable salt has the following structure. The cyclic dinucleotide analogue can be used as a regulator of a stimulator of interferon genes (STING) and a related signal path thereof, and can effectively treat and/or relieve multiple types of diseases, including but not limited to malignant tumors, inflammations, autoimmune diseases, and infectious diseases. In addition, the STING regulator can also be used as a vaccine adjuvant.
    Type: Grant
    Filed: September 18, 2019
    Date of Patent: November 26, 2024
    Assignee: SHANGHAI DE NOVO PHARMATECH CO., LTD.
    Inventors: Zhaolong Tong, Ping Qin, Fengtao Liu, Jinglu Wang, Xiaolei Deng, Hongli Guo, Dawei Chen, Daxin Gao
  • KRAS G12D INHIBITOR AND USE THEREOF
    Publication number: 20240327425
    Abstract: A KRAS inhibitor compound represented by formula (I), and an isomer or a pharmaceutically acceptable salt thereof. The compound represented by formula (I) and the composition thereof can effectively treat diseases related to KRAS mutation.
    Type: Application
    Filed: June 30, 2022
    Publication date: October 3, 2024
    Inventors: Feng WANG, Jinglu WANG, Chuanxiu ZHANG, Feng Zhou, Man ZHANG, Daxin GAO
  • CYCLIC DINUCLEOTIDE ANALOGUE, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATION
    Publication number: 20220041644
    Abstract: A cyclic dinucleotide analogue, a pharmaceutical composition thereof, and application. A cyclic dinucleotide analogue (I), an isomer thereof, a prodrug, a stable isotope derivative, or a pharmaceutically acceptable salt has the following structure. The cyclic dinucleotide analogue can be used as a regulator of a stimulator of interferon genes (STING) and a related signal path thereof, and can effectively treat and/or relieve multiple types of diseases, including but not limited to malignant tumors, inflammations, autoimmune diseases, and infectious diseases. In addition, the STING regulator can also be used as a vaccine adjuvant.
    Type: Application
    Filed: September 18, 2019
    Publication date: February 10, 2022
    Inventors: Zhaolong TONG, Ping QIN, Fengtao LIU, Jinglu WANG, Xiaolei DENG, Hongli GUO, Dawei CHEN, Daxin GAO
  • Cyano substituted heteroarylpyrimidinone derivative, preparation method and use thereof
    Patent number: 11142531
    Abstract: The present invention relates to a cyano-substituted heteroarylpyrimidinone derivative represented by formula (I), a preparation method therefor and a use thereof as a therapeutic agent, in particular a use as an acetyl-CoA carboxylase (ACC) inhibitor, and the definition of each substituent in formula (I) is the same as the definition in the description.
    Type: Grant
    Filed: March 23, 2018
    Date of Patent: October 12, 2021
    Assignee: ZHEJIANG HISUN PHARMACEUTICAL CO., LTD.
    Inventors: Hejun Lv, Dongliang Guan, Mingxiao Chen, Jinglu Wang, Lin Qian
  • CYANO SUBSTITUTED HETEROARYLPYRIMIDINONE DERIVATIVE, PREPARATION METHOD AND USE THEREOF
    Publication number: 20200102322
    Abstract: The present invention relates to a cyano-substituted heteroarylpyrimidinone derivative represented by formula (I), a preparation method therefor and a use thereof as a therapeutic agent, in particular a use as an acetyl-CoA carboxylase (ACC) inhibitor, and the definition of each substituent in formula (I) is the same as the definition in the description.
    Type: Application
    Filed: March 23, 2018
    Publication date: April 2, 2020
    Applicant: ZHEJIANG HISUN PHARMACEUTICAL CO., LTD.
    Inventors: Hejun LV, Dongliang GUAN, Mingxiao CHEN, Jinglu WANG, Lin QIAN