Patents by Inventor Jingrui Wu

Jingrui Wu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Improving agronomic characteristics in maize by modification of endogenous mads box transcription factors
    Patent number: 12371702
    Abstract: Genome edited plants, plant cells, seeds and plant parts of maize are provided where expression levels and/or activities of MADS-box transcription factors are modulated to improve one or more agronomic characteristics such as grain yield. Also provided are compositions comprising polynucleotides encoding polypeptides and guide RNAs targeted to endogenous maize MADS-box proteins including for example, targeted site-directed mutagenesis using CRISPR-associated nucleases. Additionally, various methods of employing the polynucleotides and genetic modifications in plants, such as methods for modulating expression level in a maize plant and methods for increasing yield of a maize plant are also provided herein.
    Type: Grant
    Filed: April 16, 2019
    Date of Patent: July 29, 2025
    Assignee: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: Shane E Abbitt, Mary J Frank, Shai Lawit, Rosana Melo, Mary A Rupe, Bo Shen, Jingrui Wu
  • Genes, constructs and maize event DP-202216-6
    Patent number: 12234470
    Abstract: The compositions and methods disclosed relate to DNA compositions, plant cells, seeds, plant parts that relate to maize plants with increased grain yield trait. Also provided are assays for detecting the presence of the maize DP-202216-6 event based on the DNA sequence of the recombinant construct inserted into the maize genome and the DNA sequences flanking the insertion site. Kits and conditions useful in conducting the assays are provided.
    Type: Grant
    Filed: June 23, 2021
    Date of Patent: February 25, 2025
    Assignee: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: Nathan David Coles, Olga Danilevskaya, Jeffrey Habben, Mary A Rupe, Jeffrey R Schussler, Bo Shen, Benjamin P Weers, Jingrui Wu
  • INTERACTORS AND TARGETS FOR IMPROVING PLANT AGRONOMIC CHARACTERISTICS
    Publication number: 20250011804
    Abstract: Provided are compositions comprising polynucleotides encoding polypeptides. Also provided are recombinant DNA constructs, plants, plant cells, seed, grain comprising the polynucleotides, and plants, plant cells, seed, grain comprising a genetic modification at a genomic locus encoding a polypeptide. Additionally, various methods of employing the polynucleotides and genetic modifications in plants, such as methods for modulating expression level in a plant and methods for increasing yield of a plant are also provided herein.
    Type: Application
    Filed: September 26, 2024
    Publication date: January 9, 2025
    Applicant: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: KRISTIN HAUG COLLET, ZHENGLIN HOU, SHAI LAWIT, ROSANA MELO, NICHOLAS MONGAR, JOHN VAN HEMERT, JINGRUI WU, WENGANG ZHOU
  • MADS BOX PROTEINS AND IMPROVING AGRONOMIC CHARACTERISTICS IN PLANTS
    Publication number: 20240425871
    Abstract: Provided are compositions comprising polynucleotides encoding polypeptides. Also provided are recombinant DNA constructs, plants, plant cells, seed, grain comprising the polynucleotides, and plants, plant cells, seed, grain comprising a genetic modification at a genomic locus encoding a polypeptide. Additionally, various methods of employing the polynucleotides and genetic modifications in plants, such as methods for modulating expression level in a plant and methods for increasing yield of a plant are also provided herein.
    Type: Application
    Filed: September 1, 2024
    Publication date: December 26, 2024
    Applicant: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: CARLOS M LA ROTA, ROSANA MELO, BO SHEN, CARL SIMMONS, JINGRUI WU
  • MADS box proteins and improving agronomic characteristics in plants
    Patent number: 12077766
    Abstract: Provided are compositions comprising polynucleotides encoding polypeptides. Also provided are recombinant DNA constructs, plants, plant cells, seed, grain comprising the polynucleotides, and plants, plant cells, seed, grain comprising a genetic modification at a genomic locus encoding a polypeptide. Additionally, various methods of employing the polynucleotides and genetic modifications in plants, such as methods for modulating expression level in a plant and methods for increasing yield of a plant are also provided herein.
    Type: Grant
    Filed: April 17, 2019
    Date of Patent: September 3, 2024
    Assignee: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: Carlos M La Rota, Rosana Melo, Bo Shen, Carl Simmons, Jingrui Wu
  • TRANSGENIC PLANTS WITH ENHANCED TRAITS
    Publication number: 20240102037
    Abstract: This disclosure provides transgenic plants having enhanced traits such as increased yield, enhanced nitrogen use efficiency and enhanced drought tolerance; propagules, progeny and field crops of such transgenic plants; and methods of making and using such transgenic plants. This disclosure also provides methods of producing hybrid seed from such transgenic plants, growing such seed and selecting progeny plants with enhanced traits. Also disclosed are transgenic plants with altered phenotypes which are useful for screening and selecting transgenic events for the desired enhanced trait.
    Type: Application
    Filed: July 26, 2023
    Publication date: March 28, 2024
    Inventors: Paolo Castiglioni, Jaishree M. Chittoor-Vijayanath, Barry S. Goldman, Robert J. Meister, Monnanda S. Rajani, G. Ramamohan, Naveen Silvester, Tyamagondlu V. Venkatesh, Jingrui Wu, Xiaoyun Wu
  • GENES, CONSTRUCTS AND MAIZE EVENT DP-202216-6
    Publication number: 20220380794
    Abstract: The compositions and methods disclosed relate to DNA compositions, plant cells, seeds, plant parts that relate to maize plants with increased grain yield trait. Also provided are assays for detecting the presence of the maize DP-202216-6 event based on the DNA sequence of the recombinant construct inserted into the maize genome and the DNA sequences flanking the insertion site. Kits and conditions useful in conducting the assays are provided.
    Type: Application
    Filed: June 21, 2022
    Publication date: December 1, 2022
    Applicant: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: HEATHER MARIE CHRISTENSEN, NATHAN DAVID COLES, OLGA DANILEVSKAYA, JEFFREY HABBEN, MARY A RUPE, JEFFREY R SCHUSSLER, BO SHEN, BENJAMIN P WEERS, JINGRUI WU
  • REDUCED STATURE MAIZE AND MADS-BOX TRANSCRIPTION FACTORS
    Publication number: 20220378000
    Abstract: The compositions and methods relate to shorter stature corn plants having an increased and extended expression of a MADS-box polypeptide along with one or more genetic modifications that result in shorter stature.
    Type: Application
    Filed: December 15, 2020
    Publication date: December 1, 2022
    Applicant: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: JEFFREY HABBEN, BENJAMIN P WEERS, JINGRUI WU
  • Transgenic plants with enhanced agronomic traits
    Patent number: 11479783
    Abstract: This invention provides recombinant DNA constructs, transgenic plant nuclei and cells with such recombinant DNA construct for expression of proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants. This invention also provides transgenic plants and progeny seed comprising the transgenic plant cells where the plants are selected for having an enhanced trait selected from the group of traits consisting of enhanced water use efficiency, enhanced cold tolerance, increased yield, enhanced nitrogen use efficiency, enhanced seed protein and enhanced seed oil. Also disclosed are methods for manufacturing transgenic seed and plants with enhanced traits.
    Type: Grant
    Filed: January 9, 2020
    Date of Patent: October 25, 2022
    Assignee: Monsanto Technology LLC
    Inventors: Mark Scott Abad, Jeffrey E. Ahrens, Alice Clara Augustine, Erin Bell, Robert J. Bensen, Paolo Castiglioni, Richard Eric Cerny, Shobha Char, Xianfeng Chen, Jaishree M. Chittoor-Vijayanath, Maureen Daley, Jill Deikman, Molian Deng, Todd DeZwaan, Stephen Duff, Michael D. Edgerton, Bradon J. Fabbri, Jason Fenner, Karen Gabbert, Barry S. Goldman, Deborah J. Hawkins, Steve He, Richard Johnson, Balasulojini Karunanandaa, Garrett J. Lee, Paul Loida, Savitha Madappa, Robert J. Meister, Donald E. Nelson, Anand Pandravada, Obed Patty, Ming Peng, Marie Petracek, Rajani Monnanda Somaiah, Dhanalakshmi Ramachandra, Monica P. Ravanello, Thomas G. Ruff, Rick A. Sanders, Beth Savidge, Steven H. Schwartz, Padmini Sudarshana, Jindong Sun, Rebecca L. Thompson-Mize, Virginia Ursin, Dale L. Vai, Srikanth Venkatachalayya, Tymagondlu V. Venkatesh, Kammaradi Vidya, K. Vijayalakshmi, Todd C. Weber, Jingrui Wu, Zhidong Xie, Wei Zheng
  • Genes, constructs and maize event DP-202216-6
    Patent number: 11421242
    Abstract: The compositions and methods disclosed relate to DNA compositions, plant cells, seeds, plant parts that relate to maize plants with increased grain yield trait. Also provided are assays for detecting the presence of the maize DP-202216-6 event based on the DNA sequence of the recombinant construct inserted into the maize genome and the DNA sequences flanking the insertion site. Kits and conditions useful in conducting the assays are provided.
    Type: Grant
    Filed: April 16, 2019
    Date of Patent: August 23, 2022
    Inventors: Heather Marie Christensen, Nathan David Coles, Olga Danilevskaya, Jeffrey Habben, Mary A Rupe, Jeffrey R Schussler, Bo Shen, Benjamin P Weers, Jingrui Wu
  • TRANSGENIC PLANTS WITH ENHANCED TRAITS
    Publication number: 20220154201
    Abstract: This disclosure provides transgenic plants having enhanced traits such as increased yield, enhanced nitrogen use efficiency and enhanced drought tolerance; propagules, progeny and field crops of such transgenic plants; and methods of making and using such transgenic plants. This disclosure also provides methods of producing hybrid seed from such transgenic plants, growing such seed and selecting progeny plants with enhanced traits. Also disclosed are transgenic plants with altered phenotypes which are useful for screening and selecting transgenic events for the desired enhanced trait.
    Type: Application
    Filed: February 1, 2022
    Publication date: May 19, 2022
    Applicant: Monsanto Technology LLC
    Inventors: Paolo CASTIGLIONI, Jaishree M. CHITTOOR-VIJAYANATH, Barry S. GOLDMAN, Robert J. MEISTER, Monnanda S. RAJANI, G. RAMAMOHAN, Naveen SILVESTER, Tyamagondlu V. VENKATESH, Jingrui WU, Xiaoyun WU
  • Transgenic plants with enhanced traits
    Patent number: 11268103
    Abstract: This disclosure provides transgenic plants having enhanced traits such as increased yield, enhanced nitrogen use efficiency and enhanced drought tolerance; propagules, progeny and field crops of such transgenic plants; and methods of making and using such transgenic plants. This disclosure also provides methods of producing hybrid seed from such transgenic plants, growing such seed and selecting progeny plants with enhanced traits. Also disclosed are transgenic plants with altered phenotypes which are useful for screening and selecting transgenic events for the desired enhanced trait.
    Type: Grant
    Filed: March 6, 2013
    Date of Patent: March 8, 2022
    Assignee: Monsanto Technology LLC
    Inventors: Paolo Castiglioni, Jaishree M. Chittoor-Vijayanath, Barry S. Goldman, Robert J. Meister, Monnanda S. Rajani, G. Ramamohan, Naveen Silvester, Tyamagondlu V. Venkatesh, Jingrui Wu, Xiaoyun Wu
  • GENES, CONSTRUCTS AND MAIZE EVENT DP-202216-6
    Publication number: 20210388370
    Abstract: The compositions and methods disclosed relate to DNA compositions, plant cells, seeds, plant parts that relate to maize plants with increased grain yield trait. Also provided are assays for detecting the presence of the maize DP-202216-6 event based on the DNA sequence of the recombinant construct inserted into the maize genome and the DNA sequences flanking the insertion site. Kits and conditions useful in conducting the assays are provided.
    Type: Application
    Filed: June 23, 2021
    Publication date: December 16, 2021
    Applicant: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: NATHAN DAVID COLES, OLGA DANILEVSKAYA, JEFFREY HABBEN, MARY A. RUPE, JEFFREY R. SCHUSSLER, BO SHEN, BENJAMIN P. WEERS, JINGRUI WU
  • Genes, constructs and maize event DP-202216-6
    Patent number: 11124801
    Abstract: The compositions and methods disclosed relate to DNA compositions, plant cells, seeds, plant parts that relate to maize plants with increased grain yield trait. Also provided are assays for detecting the presence of the maize DP-202216-6 event based on the DNA sequence of the recombinant construct inserted into the maize genome and the DNA sequences flanking the insertion site. Kits and conditions useful in conducting the assays are provided.
    Type: Grant
    Filed: April 17, 2019
    Date of Patent: September 21, 2021
    Inventors: Nathan David Coles, Olga Danilevskaya, Jeffrey Habben, Mary A Rupe, Jeffrey R Schussler, Bo Shen, Benjamin P Weers, Jingrui Wu
  • MODIFICATION OF GLUTAMINE SYNTHETASE TO IMPROVE YIELD IN PLANTS
    Publication number: 20210180079
    Abstract: Provided are compositions comprising polynucleotides encoding glutamine synthetase (GS) polypeptides having improved properties, such as increased enzymatic activity and/or increased thermostability. Also provided are recombinant DNA constructs, plants, plant cells, seed, grain comprising the polynucleotides. Additionally, various methods of employing the polynucleotides in plants, such as methods for increasing GS activity in a plant, methods for increase seed protein content in a seed of a plant, and methods for increasing yield of a plant, are also provided herein.
    Type: Application
    Filed: May 20, 2019
    Publication date: June 17, 2021
    Applicant: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: STEVEN HENRY BASS, ERICKA BERMUDEZ, ZHENGLIN HOU, SHAI LAWIT, MARIAN BEECHER SANDOVAL, BO SHEN, PETER THELEN, YANG WANG, ROBERT W WILLIAMS, JINGRUI WU, JUN ZHANG
  • INTERACTORS AND TARGETS FOR IMPROVING PLANT AGRONOMIC CHARACTERISTICS
    Publication number: 20210171971
    Abstract: Provided are compositions comprising polynucleotides encoding polypeptides. Also provided are recombinant DNA constructs, plants, plant cells, seed, grain comprising the polynucleotides, and plants, plant cells, seed, grain comprising a genetic modification at a genomic locus encoding a polypeptide. Additionally, various methods of employing the polynucleotides and genetic modifications in plants, such as methods for modulating expression level in a plant and methods for increasing yield of a plant are also provided herein.
    Type: Application
    Filed: April 16, 2019
    Publication date: June 10, 2021
    Applicant: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: KRISTIN HAUG COLLET, ZHENGLIN HOU, SHAI LAWIT, ROSANA MELO, NICHOLAS MONGAR, JOHN VAN HEMERT, JINGRUI WU, WENGANG ZHOU
  • MADS BOX PROTEINS AND IMPROVING AGRONOMIC CHARACTERISTICS IN PLANTS
    Publication number: 20210155951
    Abstract: Provided are compositions comprising polynucleotides encoding polypeptides. Also provided are recombinant DNA constructs, plants, plant cells, seed, grain comprising the polynucleotides, and plants, plant cells, seed, grain comprising a genetic modification at a genomic locus encoding a polypeptide. Additionally, various methods of employing the polynucleotides and genetic modifications in plants, such as methods for modulating expression level in a plant and methods for increasing yield of a plant are also provided herein.
    Type: Application
    Filed: April 17, 2019
    Publication date: May 27, 2021
    Applicant: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: CARLOS M LA ROTA, ROSANA MELO, BO SHEN, CARL SIMMONS, JINGRUI WU
  • IMPROVING AGRONOMIC CHARACTERISTICS IN MAIZE BY MODIFICATION OF ENDOGENOUS MADS BOX TRANSCRIPTION FACTORS
    Publication number: 20210155949
    Abstract: Genome edited plants, plant cells, seeds and plant parts of maize are provided where expression levels and/or activities of MADS-box transcription factors are modulated to improve one or more agronomic characteristics such as grain yield. Also provided are compositions comprising polynucleotides encoding polypeptides and guide RNAs targeted to endogenous maize MADS-box proteins including for example, targeted site-directed mutagenesis using CRISPR-associated nucleases. Additionally, various methods of employing the polynucleotides and genetic modifications in plants, such as methods for modulating expression level in a maize plant and methods for increasing yield of a maize plant are also provided herein.
    Type: Application
    Filed: April 16, 2019
    Publication date: May 27, 2021
    Applicant: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: SHANE E ABBITT, MARY J FRANK, SHAI LAWIT, ROSANA MELO, MARY A RUPE, BO SHEN, JINGRUI WU
  • GENES, CONSTRUCTS AND MAIZE EVENT DP-202216-6
    Publication number: 20210115463
    Abstract: The compositions and methods disclosed relate to DNA compositions, plant cells, seeds, plant parts that relate to maize plants with increased grain yield trait. Also provided are assays for detecting the presence of the maize DP-202216-6 event based on the DNA sequence of the recombinant construct inserted into the maize genome and the DNA sequences flanking the insertion site. Kits and conditions useful in conducting the assays are provided.
    Type: Application
    Filed: April 16, 2019
    Publication date: April 22, 2021
    Applicant: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: HEATHER MARIE CHRISTENSEN, NATHAN DAVID COLES, OLGA DANILEVSKAYA, JEFFREY HABBEN, MARY A RUPE, JEFFREY R SCHUSSLER, BO SHEN, BENJAMIN P WEERS, JINGRUI WU
  • Transgenic plants with enhanced agronomic traits
    Publication number: 20200208167
    Abstract: This invention provides recombinant DNA constructs, transgenic plant nuclei and cells with such recombinant DNA construct for expression of proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants. This invention also provides transgenic plants and progeny seed comprising the transgenic plant cells where the plants are selected for having an enhanced trait selected from the group of traits consisting of enhanced water use efficiency, enhanced cold tolerance, increased yield, enhanced nitrogen use efficiency, enhanced seed protein and enhanced seed oil. Also disclosed are methods for manufacturing transgenic seed and plants with enhanced traits.
    Type: Application
    Filed: January 9, 2020
    Publication date: July 2, 2020
    Inventors: Mark Scott Abad, Jeffrey E. Ahrens, Alice Clara Augustine, Erin Bell, Robert J. Bensen, Paolo Castiglioni, Richard Eric Cerny, Shobha Char, Xianfeng Chen, Jaishree M. Chittoor-Vijayanath, Maureen Daley, Jilll Deikman, Molian Deng, Todd DeZwaan, Stephen Duff, Michael D. Edgerton, Bradon J. Fabbri, Jason Fenner, Karen Gabbert, Barry S. Goldman, Deborah J. Hawkins, Steve He, Richard Johnson, Balasulojini Karunanandaa, Garrett J. Lee, Paul Loida, Savitha Madappa, Robert J. Meister, Donald E. Nelson, Anand Pandravada, Obed Patty, Ming Peng, Marie Petracek, Rajani Monnanda Somaiah, Dhanalakshmi Ramachandra, Monica P. Ravanello, Thomas G. Ruff, Rick A Sanders, Beth Savidge, Steven H. Schwartz, Padmini Sudarshana, Jindong Sun, Rebecca L. Thompson-Mize, Virginia Ursin, Dale L. Val, Srikanth Venkatachalayya, Tymagondlu V. Venkatesh, Kammaradi Vidya, K. Vijayalakshmi, Todd C. Weber, Jingrui Wu, Zhidong Xie, Wei Zheng