Patents by Inventor Jingwen Yao
Jingwen Yao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240125880Abstract: A method for generating magnetic resonance (MR) images of a kidney region or a brain of a subject using multinuclear magnetic resonance imaging MRI includes performing, using an MRI system, an Na-nuclei pulse sequence module to acquire a portion of a first set of MR data from the kidney or brain region of the subject and performing, using the MRI system, an H-nuclei pulse sequence module to acquire a portion of a second set of MR data from the kidney or brain region of the subject. The Na-nuclei pulse sequence module and the H-nuclei pulse sequence module may be repeated in an interleaved manner until acquisition of the first set of MR data and the second set of MR data are complete. The method further includes generating at least one Na-based image using the first set of MR data, generating at least one H-based image using the second set of MR data and displaying one or more of the at least one Na-based image and the at least one H-based image on a display.Type: ApplicationFiled: February 14, 2022Publication date: April 18, 2024Inventors: Mark Bydder, Benjamin M. Ellingson, Jingwen Yao
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Publication number: 20240028859Abstract: The disclosure provides a display card and an electronic device with a wireless communication function. The display card includes a connection interface circuit, a display chip, a wireless communication chip, and a micro-controller unit. The connection interface circuit is configured to electrically connect the display card to the electronic device. The display chip is disposed in the display card. The wireless communication chip is disposed in the display card. The micro-controller unit is disposed in the display card and is electrically connected to the connection interface circuit, the display chip, and the wireless communication chip. In response to the electronic device being in the power off mode, the micro-controller unit receives power for the electronic device through the connection interface circuit and executes the wireless communication function through the wireless communication chip. Therefore, the convenience of the user when operating the electronic device is improved.Type: ApplicationFiled: November 11, 2022Publication date: January 25, 2024Applicant: ASUS GLOBAL PTE. LTD.Inventors: Jie Zhou, Xu Wang, Chao Xu, Jingwen Yao, Xilong Du, Qi Hu
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Patent number: 10796784Abstract: A tag database establishment section converts, based on information such as an amino acid sequence of an identified peptide and m/z of a peak, a sequence tag indicating a partial sequence and information related to the tag into a database and creates a tag database. When MS2 spectrum information is obtained by measuring a target peptide, a sequence tag acquisition section executes, on the tag database, a search based on coincidence of the m/z of the peak and the like and extracts a sequence tag with high reliability. A peptide identification section performs, based on an amino acid sequence of the sequence tag, m/z of a precursor ion, and the like, a search by a sequence tag search method taking into account a post-translational modification or a variation and identifies a peptide.Type: GrantFiled: August 28, 2014Date of Patent: October 6, 2020Assignee: SHIMADZU CORPORATIONInventor: Jingwen Yao
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Patent number: 9613786Abstract: To enable more reliable detection of ion peaks from mass spectral data. Ion peaks are detected from mass spectrum by the following steps. A step of acquiring mass spectral data made up of peaks which is acquired using a mass spectrometer, the peaks having mass-to-charge ratio and intensity information, a step of classifying the peaks in the acquired mass spectral data into a plurality of classes according to the intensity of the peaks, and a step of identifying the peaks as ion peaks or noise peaks based on the intensity information of the peaks which have been classified into the plurality of classes.Type: GrantFiled: April 29, 2013Date of Patent: April 4, 2017Assignee: SHIMADZU CORPORATIONInventor: Jingwen Yao
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Publication number: 20150066380Abstract: A tag database establishment section converts, based on information such as an amino acid sequence of an identified peptide and m/z of a peak, a sequence tag indicating a partial sequence and information related to the tag into a database and creates a tag database. When MS2 spectrum information is obtained by measuring a target peptide, a sequence tag acquisition section executes, on the tag database, a search based on coincidence of the m/z of the peak and the like and extracts a sequence tag with high reliability. A peptide identification section performs, based on an amino acid sequence of the sequence tag, m/z of a precursor ion, and the like, a search by a sequence tag search method taking into account a post-translational modification or a variation and identifies a peptide.Type: ApplicationFiled: August 28, 2014Publication date: March 5, 2015Applicant: SHIMADZU CORPORATIONInventor: Jingwen YAO
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Patent number: 8694264Abstract: (EN) MS analysis, MS2 analysis, . . . , MSP analysis for peptide mixture are sequentially executed to obtain respective mass spectra (S1). At this time, an analysis in which precursor ion is changed or a different cleavage condition is set for the same precursor ion is performed plural times to put together peaks appearing in mass spectra that are obtained respectively. After the number of peaks is increased, a useful peak is extracted using commonality and complementarity of the peaks of MSm spectrum and MSm+1 spectrum and classification is performed for each type of peaks extracted to obtain an appearance frequency for each classification (S3, S4). An evaluation score on whether the extracted peak is a product ion and on a terminal is calculated based on reliability and appearance frequency that are obtained in advance (S8). The evaluation score is used in estimating sequence with the use of the extracted peak to decide and output, for example, the priority of sequence candidates (S8, S9).Type: GrantFiled: December 20, 2007Date of Patent: April 8, 2014Assignee: Shimadzu CorporationInventors: Shigeki Kajihara, Jingwen Yao, Matthew Kelly
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Publication number: 20130311109Abstract: To enable more reliable detection of ion peaks from mass spectral data. Ion peaks are detected from mass spectrum by the following steps. A step of acquiring mass spectral data made up of peaks which is acquired using a mass spectrometer, the peaks having mass-to-charge ratio and intensity information, a step of classifying the peaks in the acquired mass spectral data into a plurality of classes according to the intensity of the peaks, and a step of identifying the peaks as ion peaks or noise peaks based on the intensity information of the peaks which have been classified into the plurality of classes.Type: ApplicationFiled: April 29, 2013Publication date: November 21, 2013Applicant: SHIMADZU CORPORATIONInventor: Jingwen YAO
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Patent number: 8137982Abstract: The present invention is concerned with methods for the selection of precursor ions of a sample polypeptide for fragmentation in mass spectrometry, together with methods for determining at least one putative amino acid sequence for a sample polypeptide, apparatus and computer programs for same.Type: GrantFiled: April 13, 2011Date of Patent: March 20, 2012Assignee: Shimadzu Research Laboratory (Europe) LimitedInventors: Michael May, JingWen Yao
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Publication number: 20110208686Abstract: The present invention is concerned with methods for the selection of precursor ions of a sample polypeptide for fragmentation in mass spectrometry, together with methods for determining at least one putative amino acid sequence for a sample polypeptide, apparatus and computer programs for same.Type: ApplicationFiled: April 13, 2011Publication date: August 25, 2011Inventors: Michael May, JingWen Yao
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Patent number: 7998750Abstract: The present invention is concerned with methods for the selection of precursor ions of a sample polypeptide for fragmentation in mass spectrometry, together with methods for determining at least one putative amino acid sequence for a sample polypeptide, apparatus and computer programs for same.Type: GrantFiled: February 17, 2006Date of Patent: August 16, 2011Assignee: Shimadzu Research Laboratory (Europe) LimitedInventors: Michael May, Jingwen Yao
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Publication number: 20100299076Abstract: (EN) MS analysis, MS2 analysis, . . . , MSP analysis for peptide mixture are sequentially executed to obtain respective mass spectra (S1). At this time, an analysis in which precursor ion is changed or a different cleavage condition is set for the same precursor ion is performed plural times to put together peaks appearing in mass spectra that are obtained respectively. After the number of peaks is increased, a useful peak is extracted using commonality and complementarity of the peaks of MSm spectrum and MSm+1 spectrum and classification is performed for each type of peaks extracted to obtain an appearance frequency for each classification (S3, S4). An evaluation score on whether the extracted peak is a product ion and on a terminal is calculated based on reliability and appearance frequency that are obtained in advance (S8). The evaluation score is used in estimating sequence with the use of the extracted peak to decide and output, for example, the priority of sequence candidates (S8, S9).Type: ApplicationFiled: December 20, 2007Publication date: November 25, 2010Applicant: SHIMADZU CORPORATIONInventors: Shigeki Kajihara, Jingwen Yao, Matthew Kelly
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Publication number: 20080315081Abstract: The present invention is concerned with methods for the selection of precursor ions of a sample polypeptide for fragmentation in mass spectrometry, together with methods for determining at least one putative amino acid sequence for a sample polypeptide, apparatus and computer programs for same.Type: ApplicationFiled: February 17, 2006Publication date: December 25, 2008Applicant: SHIMADZU RESEARCH LABORATORY (EUROPE) LIMITEDInventors: Michael May, Jingwen Yao