Patents by Inventor Jingxin Wang

Jingxin Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Rapadocins, inhibitors of equilibrative nucleoside transporter 1 and uses thereof
    Patent number: 10774110
    Abstract: A compound of Formula (I), and its analogs are provided. Compositions that include Formula I can be used to inhibit human equilibrative nucleoside transporter 1, increase adenosine signaling and produce effects that include increasing antiviral activity, increasing antiparasitic activity, increasing alcohol tolerance, decreasing pain protecting from ischemia as well as many other conditions.
    Type: Grant
    Filed: February 3, 2017
    Date of Patent: September 15, 2020
    Assignee: The Johns Hopkins University
    Inventors: Jun Liu, Jingxin Wang, Zhaoli Sun, Sam Hong
  • Synthesis and composition of rapafucin libraries
    Patent number: 10662220
    Abstract: A Rapafucin library containing compounds of the general structure, (A) and (E), and a synthesis of these compounds are provided.
    Type: Grant
    Filed: February 3, 2017
    Date of Patent: May 26, 2020
    Assignee: The Johns Hopkins University
    Inventors: Jun Liu, Jingxin Wang, Zufeng Guo, Sam Hong, Wukun Liu, Hanjing Peng, Manisha Das
  • POWER ELECTRONICS CONVERTER BASED RECONFIGURABLE GRID EMULATION PLATFORM
    Publication number: 20200127456
    Abstract: A system includes a controller that is configured to generate a node control signal and a plurality of switch control signals, a plurality of programmable emulators, each of the plurality of programmable emulators being configurable as one of a plurality of node types responsive to the node control signal, and a plurality of switches that are programmable to couple ones of the plurality of programmable emulators to each other responsive to the plurality of switch control signals.
    Type: Application
    Filed: October 19, 2018
    Publication date: April 23, 2020
    Inventors: Fei Wang, Leon M. Tolbert, Yiwei MA, Kevin Tomsovic, Kai Sun, Shuoting Zhang, Jingxin Wang
  • HYBRID CYCLIC LIBRARIES AND SCREENS THEREOF
    Publication number: 20190389911
    Abstract: Provided are novel types of hybrid cyclic libraries that contain a known protein binding domain of a natural product. Also provided are synthetic methods to make such libraries and methods for the deconvolution of hits using partially split-pooled library compounds. Such methods are applicable for use with the entire human proteome to screen such libraries that bind and for the identification of hits.
    Type: Application
    Filed: September 6, 2019
    Publication date: December 26, 2019
    Inventors: Jun O. Liu, Jingxin Wang, Zufeng Guo, Wei Li, Shridhar Bhat, Manisha Das
  • Hybrid cyclic libraries and screens thereof
    Patent number: 10414801
    Abstract: Provided are novel types of hybrid cyclic libraries that contain a known protein binding domain of a natural product. Also provided are synthetic methods to make such libraries and methods for the deconvolution of hits using partially split-pooled library compounds. Such methods are applicable for use with the entire human proteome to screen such libraries that bind and for the identification of hits.
    Type: Grant
    Filed: October 9, 2017
    Date of Patent: September 17, 2019
    Assignee: The Johns Hopkins University
    Inventors: Jun O. Liu, Jingxin Wang, Zufeng Guo, Wei Li, Shridhar Bhat, Manisha Das
  • SYNTHESIS AND COMPOSITION OF RAPAFUCIN LIBRARIES
    Publication number: 20190092808
    Abstract: A Rapafucin library containing compounds of the general structure, (A) and (E), and a synthesis of these compounds are provided.
    Type: Application
    Filed: February 3, 2017
    Publication date: March 28, 2019
    Inventors: Jun Liu, Jingxin Wang, Zufeng Guo, Sam Hong, Wukun Liu, Hanjing Peng, Manisha Das
  • RAPADOCINS, INHIBITORS OF EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 1 AND USES THEREOF
    Publication number: 20190031716
    Abstract: A compound of Formula (I), and its analogs are provided. Compositions that include Formula I can be used to inhibit human equilibrative nucleoside transporter 1, increase adenosine signaling and produce effects that include increasing antiviral activity, increasing antiparasitic activity, increasing alcohol tolerance, decreasing pain protecting from ischemia as well as many other conditions.
    Type: Application
    Filed: February 3, 2017
    Publication date: January 31, 2019
    Inventors: Jun Liu, Jingxin Wang, Zhaoli Sun, Sam Hong
  • DC current controller for continuously variable series reactor
    Patent number: 10177647
    Abstract: A direct current controller includes a rectifier configured to convert alternating current input into a direct current output. A converter electrically coupled to the rectifier generates a converted direct current voltage that regulates a converted direct current from the direct current output of the rectifier and synthesizes an ac component of an alternating current grid to counteract an induced back-emf. A direct current controller central controller coupled to the converter regulates the converted direct current.
    Type: Grant
    Filed: September 9, 2016
    Date of Patent: January 8, 2019
    Assignee: UT-BATTELLE, LLC
    Inventors: Fei (Fred) Wang, Burak Ozpineci, Sheng Zheng, Steven L. Campbell, Madhu Sudhan Chinthavali, Aleksandar D. Dimitrovski, Philip R. Irminger, Omer C. Onar, Larry E. Seiber, Leon M. Tolbert, Clifford P. White, Daniel J. Costinett, Zhi Li, Jingxin Wang, Fei Yang
  • HYBRID CYCLIC LIBRARIES AND SCREENS THEREOF
    Publication number: 20180222942
    Abstract: Provided are novel types of hybrid cyclic libraries that contain a known protein binding domain of a natural product. Also provided are synthetic methods to make such libraries and methods for the deconvolution of hits using partially split-pooled library compounds. Such methods are applicable for use with the entire human proteome to screen such libraries that bind and for the identification of hits.
    Type: Application
    Filed: October 9, 2017
    Publication date: August 9, 2018
    Inventors: Jun O. Liu, Jingxin Wang, Zufeng Guo, Wei Li, Shridhar Bhat, Manisha Das
  • Hybrid cyclic libraries and screens thereof
    Patent number: 9783577
    Abstract: Provided are novel types of hybrid cyclic libraries that contain a known protein binding domain of a natural product. Also provided are synthetic methods to make such libraries and methods for the deconvolution of hits using partially split-pooled library compounds. Such methods are applicable for use with the entire human proteome to screen such libraries that bind and for the identification of hits.
    Type: Grant
    Filed: January 4, 2016
    Date of Patent: October 10, 2017
    Assignee: The Johns Hopkins University
    Inventors: Jun O. Liu, Jingxin Wang, Zufeng Guo, Wei Li, Shridhar Bhat, Manisha Das
  • DC CURRENT CONTROLLER FOR CONTINUOUSLY VARIABLE SERIES REACTOR
    Publication number: 20170077799
    Abstract: A direct current controller includes a rectifier configured to convert alternating current input into a direct current output. A converter electrically coupled to the rectifier generates a converted direct current voltage that regulates a converted direct current from the direct current output of the rectifier and synthesizes an ac component of an alternating current grid to counteract an induced back-emf. A direct current controller central controller coupled to the converter regulates the converted direct current.
    Type: Application
    Filed: September 9, 2016
    Publication date: March 16, 2017
    Inventors: Fei (Fred) Wang, Burak Ozpineci, Sheng Zheng, Steven L. Campbell, Madhu Sudhan Chinthavali, Aleksandar D. Dimitrovski, Philip R. Irminger, Omer C. Onar, Larry E. Seiber, Leon M. Tolbert, Clifford P. White, Daniel J. Costinett, Zhi Li, Jingxin Wang, Fei Yang
  • HYBRID CYCLIC LIBRARIES AND SCREENS THEREOF
    Publication number: 20160115203
    Abstract: Provided are novel types of hybrid cyclic libraries that contain a known protein binding domain of a natural product. Also provided are synthetic methods to make such libraries and methods for the deconvolution of hits using partially split-pooled library compounds. Such methods are applicable for use with the entire human proteome to screen such libraries that bind and for the identification of hits.
    Type: Application
    Filed: January 4, 2016
    Publication date: April 28, 2016
    Inventors: Jun O. Liu, Jingxin Wang, Zufeng Guo, Wei Li, Shridhar Bhat, Manisha Das
  • Hybrid cyclic libraries and screens thereof
    Patent number: 9250237
    Abstract: Provided are novel types of hybrid cyclic libraries that contain a known protein binding domain of a natural product. Also provided are synthetic methods to make such libraries and methods for the deconvolution of hits using partially split-pooled library compounds. Such methods are applicable for use with the entire human proteome to screen such libraries that bind and for the identification of hits.
    Type: Grant
    Filed: November 29, 2011
    Date of Patent: February 2, 2016
    Assignee: The Johns Hopkins University
    Inventors: Jun O. Liu, Jingxin Wang, Zufeng Guo, Wei Li, Shridhar Bhat, Manisha Das
  • METHOD, SYSTEM, AND APPARATUS FOR OVERRIDING A RING BACK SIGNAL
    Publication number: 20150189076
    Abstract: Overriding a ring back signal involves receiving a ring back signal at a communications apparatus from a communication network in response to a user-initiated connection request. The ring back signal is rendered to a user of the communications apparatus, and a user input is received at the communications device to override the ring back signal. An alternate output is rendered in place of the ring back signal.
    Type: Application
    Filed: March 12, 2015
    Publication date: July 2, 2015
    Inventors: Jingxin WANG, Bing LI, Jian YUAN, Can Feng CHEN
  • Method, system, and apparatus for overriding a ring back signal
    Patent number: 8989362
    Abstract: Overriding a ring back signal involves receiving a ring back signal at a communications apparatus from a communication network in response to a user-initiated connection request. The ring back signal is rendered to a user of the communications apparatus, and a user input is received at the communications device to override the ring back signal. An alternate output is rendered to the user in place of the ring back signal.
    Type: Grant
    Filed: June 7, 2012
    Date of Patent: March 24, 2015
    Assignee: Core Wireless Licensing, S.a.r.l.
    Inventors: Jingxin Wang, Bing Li, Jian Yuan, Can Feng Chen
  • Hybrid Cyclic Libraries and Screens Thereof
    Publication number: 20140073581
    Abstract: Provided are novel types of hybrid cyclic libraries that contain a known protein binding domain of a natural product. Also provided are synthetic methods to make such libraries and methods for the deconvolution of hits using partially split-pooled library compounds. Such methods are applicable for use with the entire human proteome to screen such libraries that bind and for the identification of hits.
    Type: Application
    Filed: November 29, 2011
    Publication date: March 13, 2014
    Inventors: Jun O. Liu, Jingxin Wang, Zufeng Guo, Wei Li, Shridhar Bhat, Manisha Das
  • METHOD, SYSTEM, AND APPARATUS FOR OVERRIDING A RING BACK SIGNAL
    Publication number: 20120250847
    Abstract: Overriding a ring back signal involves receiving a ring back signal at a communications apparatus from a communication network in response to a user-initiated connection request. The ring back signal is rendered to a user of the communications apparatus, and a user input is received at the communications device to override the ring back signal. An alternate output is rendered to the user in place of the ring back signal.
    Type: Application
    Filed: June 7, 2012
    Publication date: October 4, 2012
    Applicant: CORE WIRELESS LICENSING S.A.R.L.
    Inventors: Jingxin Wang, Bing Li, Jian Yuan, Can Feng Chen
  • Method, system, and apparatus for overriding a ring back signal
    Patent number: 8204200
    Abstract: Overriding a ring back signal involves receiving a ring back signal at a communications apparatus from a communication network in response to a user-initiated connection request. The ring back signal is rendered to a user of the communications apparatus, and a user input is received at the communications device to override the ring back signal. An alternate output is rendered to the user in place of the ring back signal.
    Type: Grant
    Filed: September 3, 2008
    Date of Patent: June 19, 2012
    Assignee: Core Wireless Licensing S.à.r.l.
    Inventors: Jingxin Wang, Bing Li, Jian Yuan, Can Feng Chen
  • Method, system, and apparatus for overriding a ring back signal
    Publication number: 20100054428
    Abstract: Overriding a ring back signal involves receiving a ring back signal at a communications apparatus from a communication network in response to a user-initiated connection request. The ring back signal is rendered to a user of the communications apparatus, and a user input is received at the communications device to override the ring back signal. An alternate output is rendered to the user in place of the ring back signal.
    Type: Application
    Filed: September 3, 2008
    Publication date: March 4, 2010
    Inventors: Jingxin Wang, Bing Li, Jian Yuan, Can Feng Chen