Abstract: A device suitable for forming spherical particle clusters from fine powder is a device through which spherical particle clusters having a controlled particle size and a controlled hardness can be prepared from the fine powder by using a rolling granulation principle without adding any solution or solid binder. In particular, the device includes the following components: a) a preforming device for preforming particle clusters formed from fine powder, so that the particle clusters have a certain strength and shape while conveying the particle clusters to a next step at a certain speed; b) a spheroidizing device for further strengthening the particle clusters formed by a) the preforming device, so that the particle clusters have a higher sphericity and hardness; and c) a grading device for sieving the particle clusters spheroidized by b) the spheroidizing device to obtain particle clusters of different particle size ranges.

Abstract: A powder rotary fluidization device and a method thereof are provided. The powder rotary fluidization device includes a support device, the support device is provided with an installing plate, the installing plate is provided with a power device and a fluidization device, and the power device is in transmission connection with the fluidization device. After a position of the fluidization device on the installing plate is adjusted through the support device, the power device is started to drive the fluidization device to rotate, and meanwhile gases are introduced into the fluidization device to process powder. and therefore the problem of poor processing effect on fine powder with high viscosity is solved through the rotatable fluidization device.

Abstract: A dry powder coating apparatus for coating pharmaceutical solid dosage forms includes a housing; a drum coater; a powder coating system; a liquid spray system; a ventilation system; a heating system; a touch screen control panel; and an operation box. The drum coater may have a truncated cone on both sides, in which one side is opened and another side is closed. The drum coater is horizontally placed inside the operation box along its axis and fixed on a rotatable shaft and a motor drives the rotatable shaft and rotates the drum coater about its own axis.

Abstract: The present disclosure provides a process of producing a dry powder coated pharmaceutical capsule. The method includes preparing a dry powder film forming polymer coating composition to be coated onto an outer surface of the capsules, a size of the particulate coating powder being in a range from about 1 nm to about 500 ?m. The capsules are placed into an interior of a rotatable housing and may be preheated. The dry powder coating composition is sprayed into the interior of the housing while the rotatable housing is rotating to produce a uniform coating of the dry powder coating composition on the outer surface of the capsules. The coated capsules are cured form a substantially uniform cured.

Abstract: The present disclosure provides powder coating compositions for pharmaceutical pellets which include one or more film forming polymers in powder form present in the composition in a range from about 1 to about 95% w/w. The compositions include one or more plasticizers in powder or liquid form present in the composition in quantity to lower the glass transition temperature of the coating composition to a temperature in a range from about 30 to 100° C. The compositions also include one or more one anti-static agents in powder or liquid form present in the composition in a range from about 0.1 to about 95% w/w as well as one or more flow enhancing agents in powder form present in the composition in a range from about 0.1 to about 25% w/w.

Abstract: A container-type apparatus for wastewater treatment with a suspended particle system, including one or multiple biological reaction zones. The biological reaction zones can be facultative, anaerobic, anoxic, and aerobic and at least one of the biological reaction zones is a suspended particle system. Particles in the suspended particle system act as the carrier of microbiota and offer better conditions for them to grow. The apparatus adopts a box structure, such as a container type, which is convenient to move, flexible to assemble, and can be used multiple times. Based on actual requirements, this apparatus can also be a structure type. The suspended particle system can increase the concentration of microorganisms significantly, improve the ability to bear impact load, produce less sludge, and without sludge expansion.

Abstract: A dry powder coating apparatus for coating pharmaceutical solid dosage forms includes a housing; a drum coater; a powder coating system; a liquid spray system; a ventilation system; a heating system; a touch screen control panel; and an operation box. The drum coater may have a truncated cone on both sides, in which one side is opened and another side is closed. The drum coater is horizontally placed inside the operation box along its axis and fixed on a rotatable shaft and a motor drives the rotatable shaft and rotates the drum coater about its own axis.

Abstract: The present disclosure provides a process of producing a dry powder coated pharmaceutical capsule. The method includes preparing a dry powder film forming polymer coating composition to be coated onto an outer surface of the capsules, a size of the particulate coating powder being in a range from about 1 nm to about 500 ?m. The capsules are placed into an interior of a rotatable housing and may be preheated. The dry powder coating composition is sprayed into the interior of the housing while the rotatable housing is rotating to produce a uniform coating of the dry powder coating composition on the outer surface of the capsules. The coated capsules are cured form a substantially uniform cured.

Abstract: The present invention provides a cage particle distribution system for wastewater treatment comprising contactors. Said contactors include shells and the interior of said shells is a hollow cavity. At least one of the side walls, the upper surface and the lower surface of said shells are equipped with through-holes. Particles are loaded inside said shells and said particles can carry some microorganisms on their surfaces at least. Said cage systems are placed in the water of a wastewater system or a wastewater treatment system and one or multiple said cage systems can be placed. Separate aeration and/or liquid distribution into each individual cage system disperse particles in the system by the gas and/or liquid, which improves the efficiency of wastewater treatment.

Abstract: An apparatus for coating pharmaceutical particles such as drug dosage forms or pellets is provided which includes a drum assembly mounted for rotation about a cylindrical axis of the drum and which includes an outer drum section and an inner perforated drum section mounted concentrically on an interior of the outer drum section such that an annular chamber is formed between the perforated inner drum section and the outer drum section. Two or more baffle plates are attached between an outer surface of the inner perforated drum and an inner surface of the outer drum which are configured to act as baffles to restrain or regulate the flow of air which define two or more compartments depending on the number of baffle plates. One end of the drum assembly includes an end plate with a central aperture for use in loading pellets into the drum and provide access to coating constituents that are pumped into the drum interior during the coating process.

Abstract: The present disclosure provides a product of coated nutrients for controlled release, a method for coating the nutrients for controlled release and a coating composition for coating the nutrients for controlled release.

Abstract: Methods for preparing the drug-coated implants include a) providing an implant; b) coating the implant with the first material which includes active pharmaceutical ingredients and the first biocompatible sustained-release polymer materials; c) coating the implant with the second material which includes the second biocompatible sustained-release polymer materials. The methods can be used to prepare a drug-coated implant and a drug coating layer.

Abstract: An apparatus for coating pharmaceutical particles such as drug dosage forms or pellets is provided which includes a drum assembly mounted for rotation about a cylindrical axis of the drum and which includes an outer drum section and an inner perforated drum section mounted concentrically on an interior of the outer drum section such that an annular chamber is formed between the perforated inner drum section and the outer drum section. Two or more baffle plates are attached between an outer surface of the inner perforated drum and an inner surface of the outer drum which are configured to act as baffles to restrain or regulate the flow of air which define two or more compartments depending on the number of baffle plates. One end of the drum assembly includes an end plate with a central aperture for use in loading pellets into the drum and provide access to coating constituents that are pumped into the drum interior during the coating process.

Abstract: The present disclosure provides a process of producing a dry powder coated solid, oral administered pharmaceutical osmotic drug delivery system. The method includes preparing a dry powder film forming polymer coating composition to be coated onto an outer surface of the cores, a size of the coating powder being in a range from about 1 nm to about 500 ?m. The osmotic drug delivery cores are placed into an interior of a rotatable housing and the cores may be preheated. The dry powder coating composition is sprayed into the interior of the housing while the housing is rotating to produce a uniform coating of the dry powder coating composition on the outer surface of the cores. The coated cores are cured form a substantially uniform cured film after which one or more orifices are produced through the uniform cured film to expose the outer surface of the cores at a position of each of the one or more orifices.

Abstract: The present disclosure provides a process of producing a dry powder coated pharmaceutical capsule. The method includes preparing a dry powder film forming polymer coating composition to be coated onto an outer surface of the capsules, a size of the particulate coating powder being in a range from about 1 nm to about 500 ?m. The capsules are placed into an interior of a rotatable housing and may be preheated. The dry powder coating composition is sprayed into the interior of the housing while the rotatable housing is rotating to produce a uniform coating of the dry powder coating composition on the outer surface of the capsules. The coated capsules are cured form a substantially uniform cured.

Abstract: The present invention provides a cage particle distribution system for wastewater treatment comprising contactors. Said contactors include shells and the interior of said shells is a hollow cavity. At least one of the side walls, the upper surface and the lower surface of said shells are equipped with through-holes. Particles are loaded inside said shells and said particles can carry some microorganisms on their surfaces at least. Said cage systems are placed in the water of a wastewater system or a wastewater treatment system and one or multiple said cage systems can be placed. Separate aeration and/or liquid distribution into each individual cage system disperse particles in the system by the gas and/or liquid, which improves the efficiency of wastewater treatment.

Abstract: The present disclosure provides a light particle system or a mixed particle system for wastewater treatment comprising a contactor. The contactor includes a gas-liquid-solid three-phase region, and the gas-liquid-solid three-phase region includes gas phase, liquid phase, and solid phase. The liquid phase is a continuous phase and the solid phase is light particles or mixed particles. The mixed particles include light particles and heavy particles. The density of the light particles is lower than the density of the liquid phase and the density of the heavy particles is higher than the density of the liquid phase. The light particles or mixed particles are able to carry some microorganisms on their surfaces at least. The light/mixed particle-suspension system in the present invention applied in wastewater treatment can increase the concentration of microorganisms significantly, improve the ability to bear impact load, produce less sludge, and without sludge expansion.

Abstract: The present disclosure provides a container-type apparatus for wastewater treatment with a suspended particle system, including one or multiple biological reaction zones. Said biological reaction zones can be facultative, anaerobic, anoxic, and aerobic and at least one of said biological reaction zones is a suspended particle system. Particles in said suspended particle system act as the carrier of microbiota and offer better conditions for them to grow. The apparatus adopts a box structure, such as a container type, which is convenient to move, flexible to assemble, and can be used for multiple times. Based on actual requirements, this apparatus can also be a structure type. The suspended particle system disclosed herein applied in wastewater treatment can increase the concentration of microorganisms significantly, improve the ability to bear impact load, produce less sludge, and without sludge expansion.

Abstract: The present disclosure discloses a slightly heavy particle system for wastewater treatment, comprising a contactor. Said contactor includes a gas-liquid-solid three-phase region, and said gas-liquid-solid three-phase region includes gas phase, liquid phase, and solid phase. Said liquid phase is the continuous phase and said solid phase is slightly heavy particles. Said slightly heavy particles are able to carry some microorganisms on their surfaces at least, and the density of said slightly heavy particles is higher than the density of said liquid. The slightly heavy particle system of the present disclosure applied in wastewater treatment can increase the concentration of microorganisms significantly, improve the ability to bear impact load, produce less sludge, and without sludge expansion. Meanwhile, the means to suspend slightly heavy particles with the combined effect of gas and liquid is able to reduce energy consumption to a larger extent.

Abstract: The present disclosure provides powder coating compositions for pharmaceutical pellets which include one or more film forming polymers in powder form present in the composition in a range from about 1 to about 95% w/w. The compositions include one or more plasticizers in powder or liquid form present in the composition in quantity to lower the glass transition temperature of the coating composition to a temperature in a range from about 30 to 100° C. The compositions also include one or more one anti-static agents in powder or liquid form present in the composition in a range from about 0.1 to about 95% w/w as well as one or more flow enhancing agents in powder form present in the composition in a range from about 0.1 to about 25% w/w.