Patents by Inventor Jingyi Wang

Jingyi Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11066403
    Abstract: The present invention relates to a solid form of a compound of Formula (I), a method for preparing the solid form, a pharmaceutical composition comprising the solid form, and use of the solid form in the treatment of Janus kinase (JAK) related diseases comprising, for example, inflammatory diseases, autoimmune diseases, and cancers.
    Type: Grant
    Filed: May 28, 2018
    Date of Patent: July 20, 2021
    Assignee: SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD.
    Inventors: Jianhua Ge, Zengying Han, Fengchun Chen, Shihu Jiao, Hong Zhang, Ping Zhang, Lichun Wang, Jingyi Wang
  • Publication number: 20210213721
    Abstract: A biaxially-oriented polyethylene (BOPE) multilayer film comprises a skin layer with a matte surface and a core, the skin layer with a matte surface comprising, in weight percent (wt %) based upon the weight of the skin layer: (1) from 20 to 80 wt % of an ethylene-based polymer, and (2) from 80 to 20 wt % of a propylene-based polymer; each of the ethylene-based polymer and the propylene-based polymer having a storage modulus, with a difference between the storage modulus of the ethylene-based polymer and the propylene-based polymer of greater than 40 megaPascals (MPa) at 110° C., and greater than 18 MPa at 120° C.
    Type: Application
    Filed: May 17, 2019
    Publication date: July 15, 2021
    Inventors: Gang Wang, Xiaobing Yun, Jianping Pan, Jingyi Xu
  • Publication number: 20210212650
    Abstract: Various methods and systems are provided for x-ray imaging. In one embodiment, a method for an image pasting examination comprises acquiring, via an optical camera and/or depth camera, image data of a subject, controlling an x-ray source and an x-ray detector according to the image data to acquire a plurality of x-ray images of the subject, and stitching the plurality of x-ray images into a single x-ray image. In this way, optimal exposure techniques may be used for individual acquisitions in an image pasting examination such that the optimal dose is utilized, stitching quality is improved, and registration failures are avoided.
    Type: Application
    Filed: January 14, 2020
    Publication date: July 15, 2021
    Inventors: Dejun Wang, Jingyi Yang, Yaan Ge, Aizhen Zhou, Katelyn Nye, Gireesha Rao, Buer Qi, Najib Akram
  • Patent number: 11045455
    Abstract: The present invention relates to an azetidine derivative for use as a Janus kinase (JAK) inhibitor, a drug composition comprising same, a preparation method therefor, and a use thereof in the treatment of JAK-related diseases comprising, for example, inflammatory diseases, autoimmune diseases, and cancers.
    Type: Grant
    Filed: January 16, 2020
    Date of Patent: June 29, 2021
    Assignee: SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD.
    Inventors: Yinong Xie, Zejin You, Zhiwen Deng, Jun Zhu, Ao Wang, Yan Feng, Dong Long, Hong Zeng, Hongmei Song, Qijun Ye, Wei Qi, Donghai Su, Lichun Wang, Jingyi Wang
  • Publication number: 20210189856
    Abstract: A hydrocarbon reservoir is treated with heat to induce gasification, water-gas shift, and/or aquathermolysis reactions to generate gases including hydrogen. The hydrogen alone is produced to the surface by using hydrogen-only membranes in the production wells.
    Type: Application
    Filed: February 7, 2017
    Publication date: June 24, 2021
    Applicant: Proton Technologies Inc.
    Inventors: Ian D. GATES, Jingyi WANG
  • Publication number: 20210179647
    Abstract: The present invention relates to compounds represented by formula (I) and formula (II) and a chiral synthesis and chiral isolation method therefor, further relating to a salt and crystal form of the compound represented by formula (I), a preparation method therefor, a pharmaceutical composition comprising the same, and use thereof in the preparation of a medicament used for the treatment of a viral infectious disease such as hepatitis B.
    Type: Application
    Filed: June 3, 2019
    Publication date: June 17, 2021
    Applicant: Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.
    Inventors: Qiang TIAN, Tianming WANG, Wei LIU, Baolei ZHANG, Mingliang ZHAO, Yufeng LIANG, Jiaqiang CAI, Lichun WANG, Jingyi WANG
  • Publication number: 20210154592
    Abstract: A method and system to treat and dry fines tailings generated from mining operations, comprising spraying the tailings material into a vacuum chamber operated at less than atmospheric pressure to separate evaporated water from the residual solid materials.
    Type: Application
    Filed: April 23, 2019
    Publication date: May 27, 2021
    Inventors: Spencer Fried, Ian D. Gates, Jingyi Wang, Yi Su
  • Publication number: 20210139785
    Abstract: The invention provides methods for pelletizing bituminous liquids by inducing endogenous asphaltenes in the liquid to form a resilient external membrane on an aliquot of the bituminous liquid, optionally with simultaneous collection of light components that result from the process of inducing endogenous asphaltene formation.
    Type: Application
    Filed: March 3, 2018
    Publication date: May 13, 2021
    Inventors: Ian Donald Gates, Jingyi Wang
  • Publication number: 20210101906
    Abstract: The disclosure relates to a bioactive molecule conjugate, preparation methods and use thereof, particularly relates to a novel bioactive molecule conjugate obtained by improving coupling of the drug and the targeting moiety in an ADC or SMDC, as well as its preparation method and use in the manufacture of a medicament for the treatment of a disease associated with an abnormal cell activity.
    Type: Application
    Filed: December 10, 2018
    Publication date: April 8, 2021
    Applicant: SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD.
    Inventors: Jiaqiang CAI, Shuai SONG, Tongtong XUE, Liang XIAO, Hanwen DENG, Qiang TIAN, Jing WANG, Dengnian LIU, Liping Liu, Haimin YU, Zhouning YANG, Xu CAO, Guoqing ZHONG, Lichun WANG, Jingyi WANG
  • Publication number: 20210052576
    Abstract: Provided are tetrahydroisoquinoline derivatives, the preparation and use thereof. More specifically, provided are the tetrahydroisoquinoline derivatives or a pharmaceutically acceptable salt, ester, stereoisomer, tautomer, polymorph, solvate, isotopically labeled compound, metabolite or prodrug thereof. Further provided are a preparation process of the compound, the intermediates, a pharmaceutical composition comprising the compound and the use thereof in the treatment or prevention of a thromboembolic disorder.
    Type: Application
    Filed: March 18, 2019
    Publication date: February 25, 2021
    Inventors: Yongyong WU, Jiaqiang CAI, Guangchao ZHANG, Shuangshuang DUAN, Chaolei WANG, Lichun WANG, Jingyi WANG
  • Publication number: 20210047905
    Abstract: A petroleum reservoir is treated with heat to induce gasification, water-gas shift, and/or aquathermolysis reactions to generate synthesis gas comprising hydrogen gas. The synthesis gas is produced to the surface using one or more production wells.
    Type: Application
    Filed: March 6, 2019
    Publication date: February 18, 2021
    Applicant: PROTON TECHNOLOGIES CANADA INC.
    Inventors: Grant D. STREM, Ian D. GATES, Jingyi WANG
  • Publication number: 20210024514
    Abstract: Disclosed are a solid form of (E)-3-((R)-4-(((R)-6-(2-chloro-4-fluorophenyl)-5-(methoxycarbonyl)-2-(thiazol-2-yl)-3,6-dihydropyrimidin-4-yl)methyl)morpholin-2-yl)acrylic acid, a preparation method therefor, a pharmaceutical composition comprising same, and the use thereof in the preparation of drugs for preventing or treating viral diseases.
    Type: Application
    Filed: May 6, 2019
    Publication date: January 28, 2021
    Applicant: SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD.
    Inventors: TIANMING WANG, CHENGXI YANG, JIAQIANG CAI, WEI LIU, BAOLEI ZHANG, QIANG TIAN, SHUAI SONG, HAO HU, WEIBIAO HAN, YOUQIANG LI, XING CHEN, LICHUN WANG, JINGYI WANG
  • Patent number: 10899786
    Abstract: Provided in the present invention are a compound of Formula (I), a pharmaceutical composition comprising the same, a method for preparing the same, and use thereof as a NS5B polymerase inhibitor, a DNA polymerase inhibitor or a reverse transcriptase inhibitor for the prevention or treatment of viral diseases or cancers.
    Type: Grant
    Filed: December 19, 2017
    Date of Patent: January 26, 2021
    Assignee: SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD.
    Inventors: Jiaqiang Cai, Shuai Song, Qiang Tian, Yitao Zhang, Haitao Huang, Guoqing Zhong, Wei Zhong, Yongjia Hao, Mingliang Zhao, Hong Zeng, Hongmei Song, Xin Zhou, Yao Liu, Yuting Tan, Lichun Wang, Jingyi Wang
  • Publication number: 20210000970
    Abstract: Disclosed in the present invention is the use of an anti-HER2 antibody-drug conjugate in cancer treatment. Further provided in the present invention is the use of a pharmaceutically acceptable salt, stereoisomer, or metabolite thereof, or a solvate of each of the foregoing in the manufacture of a medicament for the prophylaxis and/or treatment of a cancer insensitive or irresponsive to a treatment with a HER2-targeting agent.
    Type: Application
    Filed: April 30, 2019
    Publication date: January 7, 2021
    Applicant: SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD.
    Inventors: Hongmei SONG, Xiaoxi YUAN, Jing WANG, Liang XIAO, Tongtong XUE, Ping LIU, Lichun WANG, Jingyi WANG
  • Publication number: 20200407645
    Abstract: The invention provides methods for pelletizing oil liquids by inducing endogenous asphaltenes in the liquid to form a resilient external layer on an aliquot of the bituminous liquid.
    Type: Application
    Filed: February 20, 2019
    Publication date: December 31, 2020
    Applicant: SOLIDEUM INC.
    Inventors: Ian Donald GATES, Jingyi WANG
  • Publication number: 20200361911
    Abstract: Related is a nitrogen-containing benzoheterocycle compound containing a carboxylic acid group as shown in general formula (I), or a stereoisomer or pharmaceutically acceptable salt thereof. The compound has excellent pharmacokinetic properties and extremely remarkable liver targeting properties, and a pharmaceutical composition comprising the same may be used as a CCR antagonist, in particular a CCR2 and/or CCR5 antagonist and can be used in mediated disease, including, but not limited to, nonalcoholic fatty liver disease (NAFLD) or the like.
    Type: Application
    Filed: January 18, 2019
    Publication date: November 19, 2020
    Inventors: Shuai SONG, Qiang TIAN, Yongyong WU, Mingliang ZHAO, Chaolei WANG, Jiaqiang CAI, Lichun WANG, Jingyi WANG
  • Publication number: 20200347131
    Abstract: The present invention relates to the field of treatment of diseases and immunology. Specifically, the present invention relates to an anti-LAG-3 antibody or an antigen-binding fragment thereof, nucleic acid molecules for encoding said antibody and fragment, and method for preparing said antibody and fragment. The anti-LAG-3 antibody or the antigen-binding fragment thereof according to the present invention has high specificity and high affinity to LAG-3, can effectively block the binding of LAG-3 to MHC II and/or FGL1, and can inhibit and/or block intracellular signaling mediated by LAG-3 binding to MHC II and/or FGL1. Therefore, the present invention further relates to a pharmaceutical composition comprising the antibody or the antigen-binding fragment thereof, and use of the pharmaceutical composition in the preparation of drugs.
    Type: Application
    Filed: January 3, 2019
    Publication date: November 5, 2020
    Inventors: Tongtong XUE, Qiang LI, Liang XIAO, Yuncheng ZHENG, Dengnian LIU, Si CHEN, Yan HU, Lichun WANG, Jingyi WANG
  • Publication number: 20200347075
    Abstract: The disclosure relates to a bioactive molecule conjugate, preparation methods and use thereof, particularly relates to a novel bioactive molecule conjugate obtained by improving coupling of the drug and the targeting moiety in an ADC or SMDC, as well as its preparation method and use in the manufacture of a medicament for the treatment of a disease associated with an abnormal cell activity.
    Type: Application
    Filed: December 10, 2018
    Publication date: November 5, 2020
    Applicant: SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD.
    Inventors: Jiaqiang CAI, Shuai SONG, Tongtong XUE, Liang XIAO, Hanwen DENG, Qiang TIAN, Jing WANG, Dengnian LIU, Liping Liu, Haimin YU, Zhouning YANG, Xu CAO, Guoqing ZHONG, Lichun WANG, Jingyi WANG
  • Publication number: 20200339558
    Abstract: The present invention generally relates to an isoxazole derivative, a preparation therefor, and a use thereof. In particular, the present invention provides a farnesoid X receptor (FXR) agonist compound, and a stereoisomer, a tautomer, a polymorph, a solvate (e.g., a hydrate), a pharmaceutically acceptable salt, an ester, a metabolite, and an N-oxide, and the chemically protected forms and prodrugs thereof. The present invention further provides a preparation method for the compound, an intermediate thereof, and a pharmaceutical composition and kit containing the same and used thereof for treating FXR-mediated diseases or conditions.
    Type: Application
    Filed: December 7, 2018
    Publication date: October 29, 2020
    Applicant: SICHUAN KELUN-BiOTECH BIGPHARMACEUTICAL CO., LTD.
    Inventors: JINMING LIU, JIAQIANG CAI, YONGYONG WU, WEI YIN, LUCHUN WANG, JINGYI WANG
  • Publication number: 20200308214
    Abstract: Provided in the present invention are a compound of Formula (I), a pharmaceutical composition comprising the same, a method for preparing the same, and use thereof as a NS5B polymerase inhibitor, a DNA polymerase inhibitor or a reverse transcriptase inhibitor for the prevention or treatment of viral diseases or cancers.
    Type: Application
    Filed: December 19, 2017
    Publication date: October 1, 2020
    Applicant: SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD.
    Inventors: Jiaqiang CAI, Shuai SONG, Qiang TIAN, Yitao ZHANG, Haitao HUANG, Guoqing ZHONG, Wei ZHONG, Yongjia HAO, Mingliang ZHAO, Hong ZENG, Hongmei SONG, Xin ZHOU, Yao LIU, Yuting TAN, Lichun WANG, Jingyi WANG