Patents by Inventor Jingyun Wang
Jingyun Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11973141Abstract: A nanosheet semiconductor device includes a first ferroelectric region between a channel nanosheet stack and a gate contact. The channel nanosheet stack includes a plurality of channel nanosheets each connected to a source and connected to a drain and a gate surrounding the plurality of channel nanosheets and connected to the source and connected to the drain. The nanosheet semiconductor device may further include a second ferroelectric region upon a sidewall of the channel nanosheet stack. Sidewalls of the first ferroelectric region may be substantially coplanar with or inset from underlying sidewalls of the channel nanosheet stack.Type: GrantFiled: August 9, 2021Date of Patent: April 30, 2024Assignee: International Business Machines CorporationInventors: Jingyun Zhang, Reinaldo Vega, Miaomiao Wang, Takashi Ando
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Publication number: 20240124558Abstract: The embodiments of the present disclosure provide an antibody or antigen-binding fragment against SARS-CoV-2 spike(S) protein, comprising: three complementarity determining regions (HCDRs) of a heavy chain variable region or one or more variants thereof, the heavy chain variable region set forth as SEQ ID NO. 30 or SEQ ID NO. 46, each of the one or more variants having at most two amino acid changes compared to the corresponding CDR; and three complementarity determining regions (LCDRs) of a light chain variable region or one or more variants thereof, the light chain variable region set forth as SEQ ID NO. 32 or SEQ ID NO. 48, each of the one or more variants having at most two amino acid changes compared to the corresponding CDR.Type: ApplicationFiled: December 20, 2023Publication date: April 18, 2024Applicant: ASSURE TECH. (HANGZHOU) CO., LTD.Inventors: Yiding CHEN, Xiangxi WANG, Ling ZHU, Yinan JIANG, Jingyun MIAO, Lili QIN, Pingju GE
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Patent number: 11639360Abstract: Disclosed are an oxazine compound and an application thereof. The oxazine compound has a structure of a general formula F. The oxazine compound described in the disclosure is a photo/acoustic dynamic active organic molecule with near-infrared absorption-emission function as well as photosensitivity and acoustic sensitivity. Maximum absorption and emission wavelengths of the compound are both greater than 660 nanometers, and a triplet-state conversion rate of the compound is high; and under illumination or ultrasound, the compound can produce reactive oxygen species with high efficiency, which has a good killing effect on cancer cells and cancer tissues, and almost has no toxic or side effects on normal tissues while achieving photo/acoustic dynamic therapy on tumors.Type: GrantFiled: April 22, 2019Date of Patent: May 2, 2023Assignees: DALIAN UNIVERSITY OF TECHNOLOGY, DALIAN CHROMAS BIOSCIENCE CO., LTDInventors: Jiangli Fan, Qichao Yao, Haidong Li, Yana Bian, Mingle Li, Jingyun Wang, Xiaojun Peng
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Patent number: 11504428Abstract: A photosensitizer and derivative, application thereof. The photosensitizer has the structure of general formula I, wherein X is S or Se, Y is organic or inorganic ion, R1 and R2 are independently selected from H, alkyl, alkoxy, alkyl amido, alkyl azide and the like; R3 is selected from H, alkyl, alkoxy, amino sulfonyl, hydroxyl, carboxyl and the like, and L1 is a linker selected from —(CH2)n1— or —(CH2CH2O)n2—. The derivatives are molecular medicines with drug molecules of anticancer and chemotherapy or tumor targeting function connected to the said photosensitizer. The photosensitizer has excellent near infrared characteristics and low dark toxicity and is used in the field of photodynamic tumor therapy. The introduction of benzophenothiazine or benzophenoselenazine into derivatives with tumor-targeting function could improve the specific uptake of photosensitizer in tumor tissues.Type: GrantFiled: November 24, 2017Date of Patent: November 22, 2022Assignees: DALIAN UNIVERSITY OF TECHNOLOGY, DALIAN CHROMAS BIOSCTENCE CO., LTDInventors: Xiaojun Peng, Mingle Li, Jiangli Fan, Qichao Yao, Jianjun Du, Saran Long, Jingyun Wang
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Patent number: 11140561Abstract: The present disclosure provides an electronic device and method for wireless communication. The electronic device comprises: a processing circuit configured to determine a collaborative access point set for users within a predetermined range by using a wireless network topology of a wireless network as a state, and to redetermine the collaborative access point set for the users in response to a change in the wireless network topology, wherein the wireless network topology comprises a user distribution and an access point distribution.Type: GrantFiled: October 19, 2018Date of Patent: October 5, 2021Assignee: SONY CORPORATIONInventors: Youping Zhao, Jingyun Wang, Chen Sun, Xin Guo
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Publication number: 20210188875Abstract: Disclosed are an oxazine compound and an application thereof. The oxazine compound has a structure of a general formula F. The oxazine compound described in the disclosure is a photo/acoustic dynamic active organic molecule with near-infrared absorption-emission function as well as photosensitivity and acoustic sensitivity. Maximum absorption and emission wavelengths of the compound are both greater than 660 nanometers, and a triplet-state conversion rate of the compound is high; and under illumination or ultrasound, the compound can produce reactive oxygen species with high efficiency, which has a good killing effect on cancer cells and cancer tissues, and almost has no toxic or side effects on normal tissues while achieving photo/acoustic dynamic therapy on tumors.Type: ApplicationFiled: April 22, 2019Publication date: June 24, 2021Inventors: Jiangli FAN, Qichao YAO, Haidong LI, Yana BIAN, Mingle LI, Jingyun WANG, Xiaojun PENG
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Publication number: 20210030873Abstract: A photosensitizer and derivative, application thereof. The photosensitizer has the structure of general formula I, wherein X is S or Se, Y is organic or inorganic ion, R1 and R2 are independently selected from H, alkyl, alkoxy, alkyl amido, alkyl azide and the like; R3 is selected from H, alkyl, alkoxy, amino sulfonyl, hydroxyl, carboxyl and the like, and L1 is a linker selected from —(CH2)n1— or —(CH2CH2O)n2—. The derivatives are molecular medicines with drug molecules of anticancer and chemotherapy or tumor targeting function connected to the said photosensitizer. The photosensitizer has excellent near infrared characteristics and low dark toxicity and is used in the field of photodynamic tumor therapy. The introduction of benzophenothiazine or benzophenoselenazine into derivatives with tumor-targeting function could improve the specific uptake of photosensitizer in tumor tissues.Type: ApplicationFiled: November 24, 2017Publication date: February 4, 2021Applicants: DALIAN UNIVERSITY OF TECHNOLOGY, DALIAN CHROMAS BIOSCIENCE CO., LTDInventors: Xiaojun PENG, Mingle LI, Jiangli FAN, Qichao YAO, Jianjun DU, Saran LONG, Jingyun WANG
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Patent number: 10897714Abstract: Provided in the present disclosure are a wireless scene identification apparatus and method for performing identification on the scene category of a predetermined wireless scene, and a wireless communication device and system. The wireless scene identification apparatus comprises: a processing circuit, configured to classify, on the basis of features extracted from environment parameters in a predetermined wireless scene, wireless channel conditions of wireless signals in the predetermined wireless scene by means of a plurality of trained classifiers, and perform decision fusion on the classification results of the plurality of classifiers, so as to classify the wireless channel conditions as wireless channel conditions in the predetermined plurality of wireless channel conditions.Type: GrantFiled: July 12, 2017Date of Patent: January 19, 2021Assignee: SONY CORPORATIONInventors: Youping Zhao, Jingyun Wang, Chen Sun, Xin Guo
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Publication number: 20200236560Abstract: The present disclosure provides an electronic device and method for wireless communication. The electronic device comprises: a processing circuit configured to determine a collaborative access point set for users within a predetermined range by using a wireless network topology of a wireless network as a state, and to redetermine the collaborative access point set for the users in response to a change in the wireless network topology, wherein the wireless network topology comprises a user distribution and an access point distribution.Type: ApplicationFiled: October 19, 2018Publication date: July 23, 2020Applicant: Sony CorporationInventors: Youping ZHAO, Jingyun WANG, Chen SUN, Xin GUO
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Publication number: 20190166505Abstract: Provided in the present disclosure are a wireless scene identification apparatus and method for performing identification on the scene category of a predetermined wireless scene, and a wireless communication device and system. The wireless scene identification apparatus comprises: a processing circuit, configured to classify, on the basis of features extracted from environment parameters in a predetermined wireless scene, wireless channel conditions of wireless signals in the predetermined wireless scene by means of a plurality of trained classifiers, and perform decision fusion on the classification results of the plurality of classifiers, so as to classify the wireless channel conditions as wireless channel conditions in the predetermined plurality of wireless channel conditions.Type: ApplicationFiled: July 12, 2017Publication date: May 30, 2019Applicant: Sony CorporationInventors: Youping ZHAO, Jingyun WANG, Chen SUN, Xin GUO
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Patent number: 10029996Abstract: The present invention provides a category of cyano-substituted asymmetric cyanine dyes having the following general structural Formula I and its synthesizing method. The cyano-substituted asymmetric cyanine dyes in present invention are easily synthesized and have long emission wavelength, high molar extinction coefficient, high sensitivity, good light stability, high fluorescence quantum yield after binding with nucleic acid, and low cell toxicity, which is beneficial for application as fluorescent dyes and could also be used in the field of identifying nucleic acid molecules, clinical diagnostics, and immunoassay testing etc.Type: GrantFiled: September 15, 2014Date of Patent: July 24, 2018Assignee: DALIAN UNIVERSITY OF TECHNOLOGYInventors: Xiaojun Peng, Si Zhang, Jiangli Fan, Jingyun Wang
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Patent number: 9862731Abstract: The present invention provides a difluoroboron dipyrromethene fluorescent probe having a structure represented by the following general formula I, and a production method and an application thereof. Said difluoroboron dipyrromethene fluorescent probe exhibits low background fluorescence, and a rapid and significant fluorescence enhancement up to 100 times after the addition of hypochloric acid. The fluorescent intensity of said fluorescent probe shows a good linear relation with the concentration of hypochloric acid in a nanomole level, and the detection limit thereof is 0.56 nanomole. Said fluorescent probe has good selectivity since it hardly responds to other reactive oxygen species such as H2O2, O2?, TBHP, HO., TBO., 1O2 and NO., and is not interfered by pH in a wide range. Said fluorescent probe can be applied to detect hypochloric acid in living cells.Type: GrantFiled: November 26, 2014Date of Patent: January 9, 2018Assignee: DALIAN UNIVERSITY OF TECHNOLOGYInventors: Jiangli Fan, Hao Zhu, Xiaojun Peng, Jingyun Wang
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Publication number: 20170029444Abstract: The present invention provides a difluoroboron dipyrromethene fluorescent probe having a structure represented by the following general formula I, and a production method and an application thereof. Said difluoroboron dipyrromethene fluorescent probe exhibits low background fluorescence, and a rapid and significant fluorescence enhancement up to 100 times after the addition of hypochloric acid. The fluorescent intensity of said fluorescent probe shows a good linear relation with the concentration of hypochloric acid in a nanomole level, and the detection limit thereof is 0.56 nanomole. Said fluorescent probe has good selectivity since it hardly responds to other reactive oxygen species such as H2O2, O2?, TBHP, HO., TBO., 1O2 and NO., and is not interfered by pH in a wide range. Said fluorescent probe can be applied to detect hypochloric acid in living cells.Type: ApplicationFiled: November 26, 2014Publication date: February 2, 2017Inventors: Jiangli FAN, Hao ZHU, Xiaojun PENG, Jingyun WANG
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Patent number: 9182350Abstract: The present invention provides a novel category of naphthalene-based two-photon fluorescent probes having a general formula I, wherein: X is selected from the X1, X2, X3 and X4; The mentioned two-photon fluorescent probes have a low fluorescence background in the non-tumor cells and tissues, and have a strong and specific fluorescent signal in the tumor cells and tissues. These probes have a certain level of water-solubility, while having good membrane permeability. In addition, they have a bigger effective two-photon absorption cross section. The compounds of the present invention also have a lower biotoxicity, phototoxicity and photobleaching. There is sufficient difference between the spectral range thereof and that of a biological sample.Type: GrantFiled: March 5, 2012Date of Patent: November 10, 2015Assignees: DALIAN UNIVERSITY OF TECHNOLOGY, DALIAN CHROMAS BIOSCIENCE CO., LTD.Inventors: Xiaojun Peng, Hua Zhang, Jiangli Fan, Jingyun Wang
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Publication number: 20150118703Abstract: The present invention provides a category of cyano-substituted asymmetric cyanine dyes having the following general structural Formula I and its synthesizing method. The cyano-substituted asymmetric cyanine dyes in present invention are easily synthesized and have long emission wavelength, high molar extinction coefficient, high sensitivity, good light stability, high fluorescence quantum yield after binding with nucleic acid, and low cell toxicity, which is beneficial for application as fluorescent dyes and could also be used in the field of identifying nucleic acid molecules, clinical diagnostics, and immunoassay testing etc.Type: ApplicationFiled: September 15, 2014Publication date: April 30, 2015Inventors: Xiaojun PENG, SI ZHANG, JIANGLI FAN, JINGYUN WANG
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Publication number: 20150079625Abstract: The present invention provides a novel category of naphthalene-based two-photon fluorescent probes having a general formula I, wherein: X is selected from the X1, X2, X3 and X4; The mentioned two-photon fluorescent probes have a low fluorescence background in the non-tumor cells and tissues, and have a strong and specific fluorescent signal in the tumor cells and tissues. These probes have a certain level of water-solubility, while having good membrane permeability. In addition, they have a bigger effective two-photon absorption cross section. The compounds of the present invention also have a lower biotoxicity, phototoxicity and photobleaching. There is sufficient difference between the spectral range thereof and that of a biological sample.Type: ApplicationFiled: March 5, 2012Publication date: March 19, 2015Applicants: DALIAN CHROMAS BIOSCIENCE CO., LTD, DALIAN UNIVERSITY OF TECHNOLOGYInventors: Xiaojun Peng, Hua Zhang, Jiangli Fan, Jingyun Wang
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Patent number: 8962339Abstract: The present invention discloses a fluorescent probe compound which solved the problem of fluorescence quenching by Pd2+, and its preparation method and use as well. Excitation and emission wavelengths of the probe compound are in visible light region. The probe compound is highly sensitive and displays good selectivity for Pd2+ in near-neutral pH range. In detection of Pd2+ in 0-10 ppb level, fluorescence is evidently enhanced, and Pd2+ in the level as low as 5 nM can be detected. Fluorescence intensity is well linearly correlated to Pd2+ concentration. The probe compound can be used for detection of contaminating palladium and residual palladium in drug, soil, water sample and reactor.Type: GrantFiled: December 6, 2010Date of Patent: February 24, 2015Assignees: Dalian University of Technology, Dalian Chromas Bioscience Co., Ltd.Inventors: Xiaojun Peng, Jiangli Fan, Honglin Li, Jingyun Wang, Shiguo Sun
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Patent number: 8889887Abstract: A pentamethine cyanine fluorescent dye having the general formula I, a synthetic method and a use thereof are disclosed. In the general formula, X is CHO or CHCR3R4; R1 and R2 are independently selected from the group consisting of (CH2)nR7 and et al.; R3 and R4 are independently selected from the group consisting of CN, COOH and COOR16; R5, R6 and R7 are independently selected from the group consisting of H, SO3R10 and COOR11; R8 is H or C1-18 alkyl; R9 is H or CH3; R10 is N(R12R13R14R15); R11 is C1-18 alkyl; R12, R13, R14, R15 and R16 are independently selected from the group consisting of H, C1-18 alkyl, (CH2)mOR8 and (CHR9CH2O)pR8; Y? is halogen anion or OTs?; and n, m and p are integers of 0-18. The dye can be utilized to sensitively detect viscosity of micro-environment such as tissues and cells.Type: GrantFiled: January 31, 2011Date of Patent: November 18, 2014Assignees: Dalian University of Technology, Dalian Firstar Information Materials Co., Ltd.Inventors: Xiaojun Peng, Zhigang Yang, Yanxia He, Jingyun Wang, Jiangli Fan, Shiguo Sun, Fengling Song
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Patent number: 8664406Abstract: The disclosure provides fluorescence probe compounds of formula I, their preparation methods and applications. These compounds are useful in detecting mercury ions.Type: GrantFiled: December 3, 2010Date of Patent: March 4, 2014Assignees: Dalian University of Technology, Dalian Chromas Bioscience Co., Ltd.Inventors: Xiaojun Peng, Jiangli Fan, Jianjun Du, Jingyun Wang, Jianzhou Zhang, Shiguo Sun
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Publication number: 20130309715Abstract: A pentamethine cyanine fluorescent dye having the general formula I, a synthetic method and a use thereof are disclosed. In the general formula, X is CHO or CHCR3R4; R1 and R2 are independently selected from the group consisting of (CH2)nR2 and et al.; R3 and R4 are independently selected from the group consisting of CN, COOH and COOR16; R5, R6 and R7 are independently selected from the group consisting of H, SO3R10 and COOR11; R8 is H or C1-18 alkyl; R9 is H or CH3; R10 is N(R12R13R14R15); R11 is C1-18 alkyl; R12, R13, R14, R15 and R16 are independently selected from the group consisting of H, C1-18 alkyl, (CH2)mOR8 and (CHR9CH2O)pR8; Y? is halogen anion or OTs?; and n, m and p are integers of 0-18. The dye can be utilized to sensitively detect viscosity of micro-environment such as tissues and cells.Type: ApplicationFiled: January 31, 2011Publication date: November 21, 2013Inventors: Xiaojun Peng, Zhigang Yang, Yanxia He, Jingyun Wang, Jiangli Fan, Shiguo Sun, Fengling Song