Patents by Inventor Jingyun Wang

Jingyun Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11973141
    Abstract: A nanosheet semiconductor device includes a first ferroelectric region between a channel nanosheet stack and a gate contact. The channel nanosheet stack includes a plurality of channel nanosheets each connected to a source and connected to a drain and a gate surrounding the plurality of channel nanosheets and connected to the source and connected to the drain. The nanosheet semiconductor device may further include a second ferroelectric region upon a sidewall of the channel nanosheet stack. Sidewalls of the first ferroelectric region may be substantially coplanar with or inset from underlying sidewalls of the channel nanosheet stack.
    Type: Grant
    Filed: August 9, 2021
    Date of Patent: April 30, 2024
    Assignee: International Business Machines Corporation
    Inventors: Jingyun Zhang, Reinaldo Vega, Miaomiao Wang, Takashi Ando
  • Publication number: 20240124558
    Abstract: The embodiments of the present disclosure provide an antibody or antigen-binding fragment against SARS-CoV-2 spike(S) protein, comprising: three complementarity determining regions (HCDRs) of a heavy chain variable region or one or more variants thereof, the heavy chain variable region set forth as SEQ ID NO. 30 or SEQ ID NO. 46, each of the one or more variants having at most two amino acid changes compared to the corresponding CDR; and three complementarity determining regions (LCDRs) of a light chain variable region or one or more variants thereof, the light chain variable region set forth as SEQ ID NO. 32 or SEQ ID NO. 48, each of the one or more variants having at most two amino acid changes compared to the corresponding CDR.
    Type: Application
    Filed: December 20, 2023
    Publication date: April 18, 2024
    Applicant: ASSURE TECH. (HANGZHOU) CO., LTD.
    Inventors: Yiding CHEN, Xiangxi WANG, Ling ZHU, Yinan JIANG, Jingyun MIAO, Lili QIN, Pingju GE
  • Patent number: 11639360
    Abstract: Disclosed are an oxazine compound and an application thereof. The oxazine compound has a structure of a general formula F. The oxazine compound described in the disclosure is a photo/acoustic dynamic active organic molecule with near-infrared absorption-emission function as well as photosensitivity and acoustic sensitivity. Maximum absorption and emission wavelengths of the compound are both greater than 660 nanometers, and a triplet-state conversion rate of the compound is high; and under illumination or ultrasound, the compound can produce reactive oxygen species with high efficiency, which has a good killing effect on cancer cells and cancer tissues, and almost has no toxic or side effects on normal tissues while achieving photo/acoustic dynamic therapy on tumors.
    Type: Grant
    Filed: April 22, 2019
    Date of Patent: May 2, 2023
    Assignees: DALIAN UNIVERSITY OF TECHNOLOGY, DALIAN CHROMAS BIOSCIENCE CO., LTD
    Inventors: Jiangli Fan, Qichao Yao, Haidong Li, Yana Bian, Mingle Li, Jingyun Wang, Xiaojun Peng
  • Patent number: 11504428
    Abstract: A photosensitizer and derivative, application thereof. The photosensitizer has the structure of general formula I, wherein X is S or Se, Y is organic or inorganic ion, R1 and R2 are independently selected from H, alkyl, alkoxy, alkyl amido, alkyl azide and the like; R3 is selected from H, alkyl, alkoxy, amino sulfonyl, hydroxyl, carboxyl and the like, and L1 is a linker selected from —(CH2)n1— or —(CH2CH2O)n2—. The derivatives are molecular medicines with drug molecules of anticancer and chemotherapy or tumor targeting function connected to the said photosensitizer. The photosensitizer has excellent near infrared characteristics and low dark toxicity and is used in the field of photodynamic tumor therapy. The introduction of benzophenothiazine or benzophenoselenazine into derivatives with tumor-targeting function could improve the specific uptake of photosensitizer in tumor tissues.
    Type: Grant
    Filed: November 24, 2017
    Date of Patent: November 22, 2022
    Assignees: DALIAN UNIVERSITY OF TECHNOLOGY, DALIAN CHROMAS BIOSCTENCE CO., LTD
    Inventors: Xiaojun Peng, Mingle Li, Jiangli Fan, Qichao Yao, Jianjun Du, Saran Long, Jingyun Wang
  • Patent number: 11140561
    Abstract: The present disclosure provides an electronic device and method for wireless communication. The electronic device comprises: a processing circuit configured to determine a collaborative access point set for users within a predetermined range by using a wireless network topology of a wireless network as a state, and to redetermine the collaborative access point set for the users in response to a change in the wireless network topology, wherein the wireless network topology comprises a user distribution and an access point distribution.
    Type: Grant
    Filed: October 19, 2018
    Date of Patent: October 5, 2021
    Assignee: SONY CORPORATION
    Inventors: Youping Zhao, Jingyun Wang, Chen Sun, Xin Guo
  • Publication number: 20210188875
    Abstract: Disclosed are an oxazine compound and an application thereof. The oxazine compound has a structure of a general formula F. The oxazine compound described in the disclosure is a photo/acoustic dynamic active organic molecule with near-infrared absorption-emission function as well as photosensitivity and acoustic sensitivity. Maximum absorption and emission wavelengths of the compound are both greater than 660 nanometers, and a triplet-state conversion rate of the compound is high; and under illumination or ultrasound, the compound can produce reactive oxygen species with high efficiency, which has a good killing effect on cancer cells and cancer tissues, and almost has no toxic or side effects on normal tissues while achieving photo/acoustic dynamic therapy on tumors.
    Type: Application
    Filed: April 22, 2019
    Publication date: June 24, 2021
    Inventors: Jiangli FAN, Qichao YAO, Haidong LI, Yana BIAN, Mingle LI, Jingyun WANG, Xiaojun PENG
  • Publication number: 20210030873
    Abstract: A photosensitizer and derivative, application thereof. The photosensitizer has the structure of general formula I, wherein X is S or Se, Y is organic or inorganic ion, R1 and R2 are independently selected from H, alkyl, alkoxy, alkyl amido, alkyl azide and the like; R3 is selected from H, alkyl, alkoxy, amino sulfonyl, hydroxyl, carboxyl and the like, and L1 is a linker selected from —(CH2)n1— or —(CH2CH2O)n2—. The derivatives are molecular medicines with drug molecules of anticancer and chemotherapy or tumor targeting function connected to the said photosensitizer. The photosensitizer has excellent near infrared characteristics and low dark toxicity and is used in the field of photodynamic tumor therapy. The introduction of benzophenothiazine or benzophenoselenazine into derivatives with tumor-targeting function could improve the specific uptake of photosensitizer in tumor tissues.
    Type: Application
    Filed: November 24, 2017
    Publication date: February 4, 2021
    Applicants: DALIAN UNIVERSITY OF TECHNOLOGY, DALIAN CHROMAS BIOSCIENCE CO., LTD
    Inventors: Xiaojun PENG, Mingle LI, Jiangli FAN, Qichao YAO, Jianjun DU, Saran LONG, Jingyun WANG
  • Patent number: 10897714
    Abstract: Provided in the present disclosure are a wireless scene identification apparatus and method for performing identification on the scene category of a predetermined wireless scene, and a wireless communication device and system. The wireless scene identification apparatus comprises: a processing circuit, configured to classify, on the basis of features extracted from environment parameters in a predetermined wireless scene, wireless channel conditions of wireless signals in the predetermined wireless scene by means of a plurality of trained classifiers, and perform decision fusion on the classification results of the plurality of classifiers, so as to classify the wireless channel conditions as wireless channel conditions in the predetermined plurality of wireless channel conditions.
    Type: Grant
    Filed: July 12, 2017
    Date of Patent: January 19, 2021
    Assignee: SONY CORPORATION
    Inventors: Youping Zhao, Jingyun Wang, Chen Sun, Xin Guo
  • Publication number: 20200236560
    Abstract: The present disclosure provides an electronic device and method for wireless communication. The electronic device comprises: a processing circuit configured to determine a collaborative access point set for users within a predetermined range by using a wireless network topology of a wireless network as a state, and to redetermine the collaborative access point set for the users in response to a change in the wireless network topology, wherein the wireless network topology comprises a user distribution and an access point distribution.
    Type: Application
    Filed: October 19, 2018
    Publication date: July 23, 2020
    Applicant: Sony Corporation
    Inventors: Youping ZHAO, Jingyun WANG, Chen SUN, Xin GUO
  • Publication number: 20190166505
    Abstract: Provided in the present disclosure are a wireless scene identification apparatus and method for performing identification on the scene category of a predetermined wireless scene, and a wireless communication device and system. The wireless scene identification apparatus comprises: a processing circuit, configured to classify, on the basis of features extracted from environment parameters in a predetermined wireless scene, wireless channel conditions of wireless signals in the predetermined wireless scene by means of a plurality of trained classifiers, and perform decision fusion on the classification results of the plurality of classifiers, so as to classify the wireless channel conditions as wireless channel conditions in the predetermined plurality of wireless channel conditions.
    Type: Application
    Filed: July 12, 2017
    Publication date: May 30, 2019
    Applicant: Sony Corporation
    Inventors: Youping ZHAO, Jingyun WANG, Chen SUN, Xin GUO
  • Patent number: 10029996
    Abstract: The present invention provides a category of cyano-substituted asymmetric cyanine dyes having the following general structural Formula I and its synthesizing method. The cyano-substituted asymmetric cyanine dyes in present invention are easily synthesized and have long emission wavelength, high molar extinction coefficient, high sensitivity, good light stability, high fluorescence quantum yield after binding with nucleic acid, and low cell toxicity, which is beneficial for application as fluorescent dyes and could also be used in the field of identifying nucleic acid molecules, clinical diagnostics, and immunoassay testing etc.
    Type: Grant
    Filed: September 15, 2014
    Date of Patent: July 24, 2018
    Assignee: DALIAN UNIVERSITY OF TECHNOLOGY
    Inventors: Xiaojun Peng, Si Zhang, Jiangli Fan, Jingyun Wang
  • Patent number: 9862731
    Abstract: The present invention provides a difluoroboron dipyrromethene fluorescent probe having a structure represented by the following general formula I, and a production method and an application thereof. Said difluoroboron dipyrromethene fluorescent probe exhibits low background fluorescence, and a rapid and significant fluorescence enhancement up to 100 times after the addition of hypochloric acid. The fluorescent intensity of said fluorescent probe shows a good linear relation with the concentration of hypochloric acid in a nanomole level, and the detection limit thereof is 0.56 nanomole. Said fluorescent probe has good selectivity since it hardly responds to other reactive oxygen species such as H2O2, O2?, TBHP, HO., TBO., 1O2 and NO., and is not interfered by pH in a wide range. Said fluorescent probe can be applied to detect hypochloric acid in living cells.
    Type: Grant
    Filed: November 26, 2014
    Date of Patent: January 9, 2018
    Assignee: DALIAN UNIVERSITY OF TECHNOLOGY
    Inventors: Jiangli Fan, Hao Zhu, Xiaojun Peng, Jingyun Wang
  • Publication number: 20170029444
    Abstract: The present invention provides a difluoroboron dipyrromethene fluorescent probe having a structure represented by the following general formula I, and a production method and an application thereof. Said difluoroboron dipyrromethene fluorescent probe exhibits low background fluorescence, and a rapid and significant fluorescence enhancement up to 100 times after the addition of hypochloric acid. The fluorescent intensity of said fluorescent probe shows a good linear relation with the concentration of hypochloric acid in a nanomole level, and the detection limit thereof is 0.56 nanomole. Said fluorescent probe has good selectivity since it hardly responds to other reactive oxygen species such as H2O2, O2?, TBHP, HO., TBO., 1O2 and NO., and is not interfered by pH in a wide range. Said fluorescent probe can be applied to detect hypochloric acid in living cells.
    Type: Application
    Filed: November 26, 2014
    Publication date: February 2, 2017
    Inventors: Jiangli FAN, Hao ZHU, Xiaojun PENG, Jingyun WANG
  • Patent number: 9182350
    Abstract: The present invention provides a novel category of naphthalene-based two-photon fluorescent probes having a general formula I, wherein: X is selected from the X1, X2, X3 and X4; The mentioned two-photon fluorescent probes have a low fluorescence background in the non-tumor cells and tissues, and have a strong and specific fluorescent signal in the tumor cells and tissues. These probes have a certain level of water-solubility, while having good membrane permeability. In addition, they have a bigger effective two-photon absorption cross section. The compounds of the present invention also have a lower biotoxicity, phototoxicity and photobleaching. There is sufficient difference between the spectral range thereof and that of a biological sample.
    Type: Grant
    Filed: March 5, 2012
    Date of Patent: November 10, 2015
    Assignees: DALIAN UNIVERSITY OF TECHNOLOGY, DALIAN CHROMAS BIOSCIENCE CO., LTD.
    Inventors: Xiaojun Peng, Hua Zhang, Jiangli Fan, Jingyun Wang
  • Publication number: 20150118703
    Abstract: The present invention provides a category of cyano-substituted asymmetric cyanine dyes having the following general structural Formula I and its synthesizing method. The cyano-substituted asymmetric cyanine dyes in present invention are easily synthesized and have long emission wavelength, high molar extinction coefficient, high sensitivity, good light stability, high fluorescence quantum yield after binding with nucleic acid, and low cell toxicity, which is beneficial for application as fluorescent dyes and could also be used in the field of identifying nucleic acid molecules, clinical diagnostics, and immunoassay testing etc.
    Type: Application
    Filed: September 15, 2014
    Publication date: April 30, 2015
    Inventors: Xiaojun PENG, SI ZHANG, JIANGLI FAN, JINGYUN WANG
  • Publication number: 20150079625
    Abstract: The present invention provides a novel category of naphthalene-based two-photon fluorescent probes having a general formula I, wherein: X is selected from the X1, X2, X3 and X4; The mentioned two-photon fluorescent probes have a low fluorescence background in the non-tumor cells and tissues, and have a strong and specific fluorescent signal in the tumor cells and tissues. These probes have a certain level of water-solubility, while having good membrane permeability. In addition, they have a bigger effective two-photon absorption cross section. The compounds of the present invention also have a lower biotoxicity, phototoxicity and photobleaching. There is sufficient difference between the spectral range thereof and that of a biological sample.
    Type: Application
    Filed: March 5, 2012
    Publication date: March 19, 2015
    Applicants: DALIAN CHROMAS BIOSCIENCE CO., LTD, DALIAN UNIVERSITY OF TECHNOLOGY
    Inventors: Xiaojun Peng, Hua Zhang, Jiangli Fan, Jingyun Wang
  • Patent number: 8962339
    Abstract: The present invention discloses a fluorescent probe compound which solved the problem of fluorescence quenching by Pd2+, and its preparation method and use as well. Excitation and emission wavelengths of the probe compound are in visible light region. The probe compound is highly sensitive and displays good selectivity for Pd2+ in near-neutral pH range. In detection of Pd2+ in 0-10 ppb level, fluorescence is evidently enhanced, and Pd2+ in the level as low as 5 nM can be detected. Fluorescence intensity is well linearly correlated to Pd2+ concentration. The probe compound can be used for detection of contaminating palladium and residual palladium in drug, soil, water sample and reactor.
    Type: Grant
    Filed: December 6, 2010
    Date of Patent: February 24, 2015
    Assignees: Dalian University of Technology, Dalian Chromas Bioscience Co., Ltd.
    Inventors: Xiaojun Peng, Jiangli Fan, Honglin Li, Jingyun Wang, Shiguo Sun
  • Patent number: 8889887
    Abstract: A pentamethine cyanine fluorescent dye having the general formula I, a synthetic method and a use thereof are disclosed. In the general formula, X is CHO or CHCR3R4; R1 and R2 are independently selected from the group consisting of (CH2)nR7 and et al.; R3 and R4 are independently selected from the group consisting of CN, COOH and COOR16; R5, R6 and R7 are independently selected from the group consisting of H, SO3R10 and COOR11; R8 is H or C1-18 alkyl; R9 is H or CH3; R10 is N(R12R13R14R15); R11 is C1-18 alkyl; R12, R13, R14, R15 and R16 are independently selected from the group consisting of H, C1-18 alkyl, (CH2)mOR8 and (CHR9CH2O)pR8; Y? is halogen anion or OTs?; and n, m and p are integers of 0-18. The dye can be utilized to sensitively detect viscosity of micro-environment such as tissues and cells.
    Type: Grant
    Filed: January 31, 2011
    Date of Patent: November 18, 2014
    Assignees: Dalian University of Technology, Dalian Firstar Information Materials Co., Ltd.
    Inventors: Xiaojun Peng, Zhigang Yang, Yanxia He, Jingyun Wang, Jiangli Fan, Shiguo Sun, Fengling Song
  • Patent number: 8664406
    Abstract: The disclosure provides fluorescence probe compounds of formula I, their preparation methods and applications. These compounds are useful in detecting mercury ions.
    Type: Grant
    Filed: December 3, 2010
    Date of Patent: March 4, 2014
    Assignees: Dalian University of Technology, Dalian Chromas Bioscience Co., Ltd.
    Inventors: Xiaojun Peng, Jiangli Fan, Jianjun Du, Jingyun Wang, Jianzhou Zhang, Shiguo Sun
  • Publication number: 20130309715
    Abstract: A pentamethine cyanine fluorescent dye having the general formula I, a synthetic method and a use thereof are disclosed. In the general formula, X is CHO or CHCR3R4; R1 and R2 are independently selected from the group consisting of (CH2)nR2 and et al.; R3 and R4 are independently selected from the group consisting of CN, COOH and COOR16; R5, R6 and R7 are independently selected from the group consisting of H, SO3R10 and COOR11; R8 is H or C1-18 alkyl; R9 is H or CH3; R10 is N(R12R13R14R15); R11 is C1-18 alkyl; R12, R13, R14, R15 and R16 are independently selected from the group consisting of H, C1-18 alkyl, (CH2)mOR8 and (CHR9CH2O)pR8; Y? is halogen anion or OTs?; and n, m and p are integers of 0-18. The dye can be utilized to sensitively detect viscosity of micro-environment such as tissues and cells.
    Type: Application
    Filed: January 31, 2011
    Publication date: November 21, 2013
    Inventors: Xiaojun Peng, Zhigang Yang, Yanxia He, Jingyun Wang, Jiangli Fan, Shiguo Sun, Fengling Song