Abstract: Provided is a vessel assembly including: a vessel having a vessel inlet through which contents are stored and discharged; a vessel cap coupled to the vessel inlet; and a sealing member attached to an upper end of the vessel inlet to seal the vessel. The vessel cap includes: a side wall part having a female threaded portion formed on an inner circumferential surface of the side wall part, which is screw-coupled to a male threaded portion formed on an outer circumferential surface of the vessel inlet; an upper part integrally formed at an upper end of the side wall part; and a contact part protruding from the inner circumferential surface of the side wall part with a gap from a bottom surface of the upper part and is configured to closely adhere to the vessel inlet even after the sealing member is removed.

Abstract: A compound of the present invention, which is a tricyclic derivative represented by chemical formula 1 or a pharmaceutically acceptable salt thereof, has an excellent inhibitory effect on serotonin activity and a pharmaceutical composition comprising same can be thus advantageously used for preventing or treating a metabolic disease associated with serotonin activation, etc.

Abstract: The present invention relates to a vacuum drying method for botulinum toxin, and specifically to a vacuum drying method for botulinum toxin, comprising the steps of: a) first drying of a solution containing botulinum toxin at a temperature of 5° C. to 30° C. under a pressure of 0.01 to 2 mmHg; b) a second drying of the first-dried product obtained in step a) at a temperature of 5° C. to 20° C. under a pressure of 0.01 to 1 mmHg; and c) final drying of the second-dried product obtained in step b) at a temperature of 5° C. to 30° C. under a pressure of 0.01 to 0.5 mmHg. The present invention can advantageously improve yield, stability and manufacturing efficiency, compared to conventional methods for vacuum drying botulinum toxin by freeze-drying.

Abstract: The present invention relates to a container lid, and a container assembly having same coupled thereto and, more specifically, to a container lid coupled to a container inlet through which contents are received, and a container assembly having the container lid coupled thereto. Disclosed is a container assembly comprising: a container for receiving contents; a container lid coupled to the container inlet; and a sealing member having a bottom surface attached to an upper end of the container inlet of the container, and coupled to the container lid, wherein, when the container lid is separated from the container by means of rotation, adhesiveness between the sealing member and the container lid is greater than adhesiveness between the container inlet and the sealing member such that the sealing member is separated from the container inlet.

Abstract: Provided are a container cap coupled to the mouth of a container in which contents are contained; and a container to which the container cap is coupled. The container cap includes: a main body part coupled to a container inlet of a container and having an opening formed on an upper side thereof; a cover part connected to the main body part by a hinge part and opening and closing an upper opening of the main body part by hinge rotation; a separation part connected to the cover part by a first connection part and connected to the main body part by a second connection part detachably; and a fixing part formed on the cover part so that the separation part is fixedly coupled thereto after the second connection part is separated by a user's manipulation so that the cover part can be separated from the main body part.

Abstract: A container cap which is combined with a container containing a beverage or the like, and a container combined with the container cap. The container cap is combined with a container inlet of a container body. A plurality of close contact portions in contact with the container inlet are formed, and the close contact portions form a closed curve enclosing the container inlet so as to block inflow of external air from the outside into the container body.

Abstract: The present invention relates to a container cap and, more specifically, to: a container cap which is coupled to the mouth of a container in which contents are contained; and a container having same coupled thereto. The present invention provides a container cap comprising: a body part coupled to the mouth of a container in which contents are contained, and having an opening at the top thereof, a cover part coupled to the body part so as to open and close the top opening of the body part; and a separation part integrally connected to a first member, which is one of the body part and the cover part, by a first connection part, and integrally but detachably connected to a second member, which is the other of the body part and the cover part, by a second connection part, wherein the second connection part is detached by a user's manipulation so as to allow the cover part to be separated from the body part.

Abstract: Provided are a container cap coupled to the mouth of a container in which contents are contained; and a container to which the container cap is coupled. The container cap includes: a main body part coupled to a container inlet of a container and having an opening formed on an upper side thereof; a cover part connected to the main body part by a hinge part and opening and closing an upper opening of the main body part by hinge rotation; a separation part connected to the cover part by a first connection part and connected to the main body part by a second connection part detachably; and a fixing part formed on the cover part so that the separation part is fixedly coupled thereto after the second connection part is separated by a user's manipulation so that the cover part can be separated from the main body part.

Abstract: A container cap which is combined with a container containing a beverage or the like, and a container combined with the container cap. The container cap is combined with a container inlet of a container body. A plurality of close contact portions in contact with the container inlet are formed, and the close contact portions form a closed curve enclosing the container inlet so as to block inflow of external air from the outside into the container body.

Abstract: The present invention relates to a container cap and, more specifically, to: a container cap which is coupled to the mouth of a container in which contents are contained; and a container having same coupled thereto. The present invention provides a container cap comprising: a body part coupled to the mouth of a container in which contents are contained, and having an opening at the top thereof; a cover part coupled to the body part so as to open and close the top opening of the body part; and a separation part integrally connected to a first member, which is one of the body part and the cover part, by a first connection part, and integrally but detachably connected to a second member, which is the other of the body part and the cover part, by a second connection part, wherein the second connection part is detached by a user's manipulation so as to allow the cover part to be separated from the body part.

Abstract: Disclosed is a container stopper (100) coupled to a container inlet (12) of a container (10) in which content is held, the container stopper comprising: a stopper body (110) that is coupled to the container inlet (12) and has, on the upper side thereof, an auxiliary space (S1) in which auxiliary content (42) having a granular structure is held; and an upper cover (120) that is coupled to the stopper body (110), forms the auxiliary space (S1) together with the stopper body (110), and covers the auxiliary space (S1).

Abstract: A quinazoline-based compound is represented by Formula 1 or Formula 2. The compound can effectively activate the BKCa channels, and thus may be used for preventing or treating the overactive bladder caused by inactivation or decrease in activity of the BKCa channels. The compound can be included in a pharmaceutical composition or health function food for improving urinary function.

Abstract: Provided are a container cap coupled to the mouth of a container in which contents are contained; and a container to which the container cap is coupled. The container cap includes: a main body part coupled to a container inlet of a container and having an opening formed on an upper side thereof; a cover part connected to the main body part by a hinge part and opening and closing an upper opening of the main body part by hinge rotation; a separation part connected to the cover part by a first connection part and connected to the main body part by a second connection part detachably; and a fixing part formed on the cover part so that the separation part is fixedly coupled thereto after the second connection part is separated by a user's manipulation so that the cover part can be separated from the main body part.

Abstract: The present invention relates to a container cap and, more specifically, to a container cap coupled to a container inlet, and a container to which same is coupled. Disclosed is the container cap comprising: a cap body (100) coupled to a container inlet (12) of the container (10) in which contents are contained; and an upper lid (200) coupled to the cap body (100) to cover the upper side of the cap body (100), wherein the cap body (100) includes an outlet plate (110) which is fractured from an upper plate part (101) to form a discharge hole (102) through which the contents contained in the container (10) are discharged, and the upper lid (200) includes a pushing part (210) which is formed in correspondence to the outlet plate (110) and which fractures the outlet plate (110) by means of the vertical movement thereof.

Abstract: The present invention relates to a container cap and, more specifically, to: a container cap which is coupled to the mouth of a container in which contents are contained; and a container having same coupled thereto. The present invention provides a container cap comprising: a body part coupled to the mouth of a container in which contents are contained, and having an opening at the top thereof; a cover part coupled to the body part so as to open and close the top opening of the body part; and a separation part integrally connected to a first member, which is one of the body part and the cover part, by a first connection part, and integrally but detachably connected to a second member, which is the other of the body part and the cover part, by a second connection part, wherein the second connection part is detached by a user's manipulation so as to allow the cover part to be separated from the body part.

Abstract: The present invention relates to a vacuum drying method for botulinum toxin, and specifically to a vacuum drying method for botulinum toxin, comprising the steps of: a) first drying of a solution containing botulinum toxin at a temperature of 5° C. to 30° C. under a pressure of 0.01 to 2 mmHg; b) a second drying of the first-dried product obtained in step a) at a temperature of 5° C. to 20° C. under a pressure of 0.01 to 1 mmHg; and c) final drying of the second-dried product obtained in step b) at a temperature of 5° C. to 30° C. under a pressure of 0.01 to 0.5 mmHg. The present invention can advantageously improve yield, stability and manufacturing efficiency, compared to conventional methods for vacuum drying botulinum toxin by freeze-drying.

Abstract: The present invention relates to a container lid, and a container assembly having same coupled thereto and, more specifically, to a container lid coupled to a container inlet through which contents are received, and a container assembly having the container lid coupled thereto. Disclosed is a container assembly comprising: a container for receiving contents; a container lid coupled to the container inlet; and a sealing member having a bottom surface attached to an upper end of the container inlet of the container, and coupled to the container lid, wherein, when the container lid is separated from the container by means of rotation, adhesiveness between the sealing member and the container lid is greater than adhesiveness between the container inlet and the sealing member such that the sealing member is separated from the container inlet.

Abstract: Disclosed is a container stopper (100) coupled to a container inlet (12) of a container (10) in which content is held, the container stopper comprising: a stopper body (110) that is coupled to the container inlet (12) and has, on the upper side thereof, an auxiliary space (S1) in which auxiliary content (42) having a granular structure is held; and an upper cover (120) that is coupled to the stopper body (110), forms the auxiliary space (S1) together with the stopper body (110), and covers the auxiliary space (S1).

Abstract: A compound of the present invention, which is a tricyclic derivative represented by chemical formula 1 or a pharmaceutically acceptable salt thereof, has an excellent inhibitory effect on serotonin activity and a pharmaceutical composition comprising same can be thus advantageously used for preventing or treating a metabolic disease associated with serotonin activation, etc.

Abstract: A container cap which is combined with a container containing a beverage or the like, and a container combined with the container cap. The container cap is combined with a container inlet of a container body. A plurality of close contact portions in contact with the container inlet are formed, and the close contact portions form a closed curve enclosing the container inlet so as to block inflow of external air from the outside into the container body.