Patents by Inventor Jinheng GAO

Jinheng GAO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SALT AND CRYSTALLINE FORMS OF FGFR4 INHIBITOR AND USES THEREOF
    Publication number: 20240174681
    Abstract: The present invention relates to a crystalline form and/or maleate, phosphate, L-tartrate, and adipate of the compound represented by the structural formula I, and various crystalline forms of various salt forms, and preparation methods and applications thereof.
    Type: Application
    Filed: March 26, 2021
    Publication date: May 30, 2024
    Applicant: BETTA PHARMACEUTICALS CO., LTD
    Inventors: Jinheng GAO, Xiaofeng XU, Liang CHEN, Zhongxin SUN, Yun ZHANG, Xiangyong LIU, Lieming DING, Jiabing WANG
  • BICYCLIC COMPOUNDS, COMPOSITIONS AND USE THEREOF
    Publication number: 20230391779
    Abstract: The present invention relates to compounds of Formula (I), pharmaceutical compositions comprising such compounds and use thereof. The compounds are useful in treating, preventing or ameliorating diseases or disorders such as cancer.
    Type: Application
    Filed: August 17, 2021
    Publication date: December 7, 2023
    Applicant: Betta Pharmaceuticals Co., Ltd.
    Inventors: Xiaofeng XU, Jinheng GAO, Hongfei RONG, Xizhen SONG, Jie CHEN, Xiangyong LIU, Hongling SHEN, Jing GUO, Dan YAN, Hong LAN, Lieming DING, Jiabing WANG
  • FGFR4 INHIBITOR AND USE THEREOF
    Publication number: 20220002307
    Abstract: Disclosed is a compound as a fibroblast growth factor receptor 4 (FGFR4) inhibitor (as shown in formula (I)), and a pharmaceutical composition thereof and a preparation method therefor, as well as the use of same in the treatment of FGFR4-mediated diseases. The above-mentioned compounds act by participating in a number of processes, such as regulating cell proliferation, apoptosis, migration, neovascularization.
    Type: Application
    Filed: September 26, 2019
    Publication date: January 6, 2022
    Inventors: Jinheng GAO, Zhongxin SUN, Yun ZHANG, Xiaofeng XU, Xiangyong LIU, Jiabing WANG, Lieming DING
  • Octahydroanthracene compound, preparation method and application thereof
    Patent number: 10399931
    Abstract: An octahydroanthracene compound having the structure shown in formula (I) and (II), preparation method and application thereof are disclosed. The octahydroanthracene compound has a good therapeutic effect on tumors and neurodegenerative diseases. The preparation of the octahydroanthracene compound is mainly carried out by using benzene as a starting material, and being subjected to Friedel-Crafts reaction, nitration, reduction, (sulfo-) amide formation, reduction, urea formation or amide formation, thus obtaining a target compound.
    Type: Grant
    Filed: March 23, 2017
    Date of Patent: September 3, 2019
    Assignees: SHANDONG XINHUA PHARMACEUTICAL CO., LTD., SHENYANG PHARMACEUTICAL UNIVERSITY
    Inventors: Guoliang Chen, Zhonghui Zheng, Libo Zou, Daiming Zhang, Chunling Yuan, Fulong Ren, Xuefei Bao, Jinheng Gao, Linbo Zhou, Wuhong Fang
  • Octahydroanthracene Compound, Preparation Method and Application Thereof
    Publication number: 20190071393
    Abstract: An octahydroanthracene compound having the structure shown in formula (I) and (II), preparation method and application thereof are disclosed. The octahydroanthracene compound has a good therapeutic effect on tumors and neurodegenerative diseases. The preparation of the octahydroanthracene compound is mainly carried out by using benzene as a starting material, and being subjected to Friedel-Crafts reaction, nitration, reduction, (sulfo-) amide formation, reduction, urea formation or amide formation, thus obtaining a target compound.
    Type: Application
    Filed: March 23, 2017
    Publication date: March 7, 2019
    Applicants: SHENYANG PHARMACEUTICAL UNIVERSITY, SHANDONG XINHUA PHARMACEUTICAL CO., LTD.
    Inventors: Guoliang CHEN, Zhonghui ZHENG, Libo ZOU, Daiming ZHANG, Chunling YUAN, Fulong REN, Xuefei BAO, Jinheng GAO, Linbo ZHOU, Wuhong FANG
  • Substituted quinazoline compounds and preparation and uses thereof
    Patent number: 10196383
    Abstract: The present invention relates quinazolinone compounds of Formula (I), as well as their preparation and uses, and further relates pharmaceutical compositions comprising these compounds and their uses; wherein the compounds or pharmaceutical compositions disclosed herein can be used for antagonizing the orexin receptor. The present invention also relates to uses of the compounds or pharmaceutical compositions in treating or preventing neurological and psychiatric disorders and diseases of the central nervous system in mammals, especially in humans.
    Type: Grant
    Filed: July 14, 2016
    Date of Patent: February 5, 2019
    Assignee: SUNSHINE LAKE PHARMA CO., LTD.
    Inventors: Yingjun Zhang, Chuanfei Jin, Jinheng Gao, Ji Zhang
  • SUBSTITUTED QUINAZOLINE COMPOUNDS AND PREPARATION AND USES THEREOF
    Publication number: 20180215737
    Abstract: The present invention relates quinazolinone compounds of Formula (I), as well as their preparation and uses, and further relates pharmaceutical compositions comprising these compounds and their uses; wherein the compounds or pharmaceutical compositions disclosed herein can be used for antagonizing the orexin receptor. The present invention also relates to uses of the compounds or pharmaceutical compositions in treating or preventing neurological and psychiatric disorders and diseases of the central nervous system in mammals, especially in humans.
    Type: Application
    Filed: July 14, 2016
    Publication date: August 2, 2018
    Applicant: Sunshine Lake Pharma Co., Ltd.
    Inventors: Yingjun ZHANG, Chuanfei JIN, Jinheng GAO, Ji ZHANG