Abstract: The present invention relates to an antigen-binding molecule comprising a heavy chain variable region comprising a heavy-chain complementarity-determining region 1 (HCDR1) comprising an amino acid sequence represented by Sequence No. 1, an HCDR2 comprising an amino acid sequence represented by Sequence No. 2, and an HCDR3 comprising an amino acid sequence represented by Sequence No. 3; a light-chain variable region comprising a light-chain complementarity-determining region 1 (LCDR1) comprising an amino acid sequence represented by Sequence No. 4, an LCDR2 comprising an amino acid sequence represented by Sequence No. 5, and an LCDR3 comprising an amino acid sequence represented by Sequence No. 6; wherein the antigen-binding molecule is a T cell receptor (TCR); and to a cell line expressing the same.

Abstract: A peptide according to an embodiment has the amino acid sequence SEQ ID NO: 1 or 2. The peptide may have an amino group at C-terminus. The peptide may have at least one amino acid. The peptide may have excellent solubility and stability such that they are advantageous for formulation when manufacturing cosmetics or drugs containing the same, thereby improving skin wrinkles, sensitive skin and dermatitis, promoting hair growth, and enhancing drug efficacy for metabolic diseases.

Abstract: The present invention relates to a composition comprising adiponectin-derived peptide fragments and, more specifically, to a cosmetic composition and pharmaceutical composition for promoting hair growth comprising, as an active ingredient, one or more adiponectin-derived peptides selected from the group consisting of amino acid sequences of SEQ ID NOS: 1 to 21. The adiponectin-derived peptides activate the cell division of dermal papilla cells and outer root sheath cells of hair follicles, promote hair growth in the hair follicles, and also increase the expression of hair growth factors in the dermal papilla cells, and thus a composition of the present invention comprising the adiponectin-derived peptides can be effectively used to promote hair growth and inhibit hair loss.

Abstract: The present invention relates to a composition comprising adiponectin-derived peptide fragments and, more specifically, to a cosmetic composition and pharmaceutical composition for promoting hair growth comprising, as an active ingredient, one or more adiponectin-derived peptides selected from the group consisting of amino acid sequences of SEQ ID NOS: 1 to 21. The adiponectin-derived peptides activate the cell division of dermal papilla cells and outer root sheath cells of hair follicles, promote hair growth in the hair follicles, and also increase the expression of hair growth factors in the dermal papilla cells, and thus a composition of the present invention comprising the adiponectin-derived peptides can be effectively used to promote hair growth and inhibit hair loss.

Abstract: The present invention relates to a novel compound having an effect of inhibiting platelet aggregation and a salt thereof and, more specifically, to: a novel platelet aggregation inhibitor specifically inhibiting shear stress-induced platelet aggregation; a pharmaceutical composition containing the same as an active ingredient; and a preparation method therefor.

Abstract: The present invention relates to a novel compound having an effect of inhibiting platelet aggregation and a salt thereof and, more specifically, to: a novel platelet aggregation inhibitor specifically inhibiting shear stress-induced platelet aggregation; a pharmaceutical composition containing the same as an active ingredient; and a preparation method therefor.

Abstract: TRPV1 inhibitory peptides and a composition for skin-aging prevention and wrinkle improvement comprising the same as an active ingredient are described. The TRPV1 inhibitory peptide of the present subject matter inhibits the expressions of MMP and proinflammatory cytokines induced by UV exposure and reduces skinfold thickness and intracellular Ca2+ influx, so that it can be effectively used as an active ingredient of the composition for skin-aging prevention, wrinkle improvement, skin-whitening, or alleviating inflammation, irritation, or pain.

Abstract: Provided is a system and method for evaluating laser treatment, for converting the attribute of a laser beam and numerically evaluating proficiency of a laser treatment operator by processing data obtained by photographing the converted laser beam so as to use the evaluated data as training data. The laser treatment evaluating system includes an attenuation unit for attenuating intensity of a laser beam transmitted through a transmissive plate, a camera for photographing the laser beam transmitted through the attenuation unit, and an image data processing apparatus connected to the camera, for processing an image captured by the camera, tracking a trajectory of a laser beam on the transmissive plate, and calculating a distribution state of spots on which the laser beam on the transmissive plate is emitted.

Abstract: The present invention relates to a method for calculating a thermal protection factor, wherein the method comprises the steps of: applying heat to a first area coated with a thermal protection material, and a second area not coated with the thermal protection material; measuring the respective saturation temperatures of the first area and second area; calculating a first energy by dividing the energy corresponding to the heat applied to the first area by the saturation temperature of the first area; calculating a second energy by dividing the energy corresponding to the heat applied to the second area by the saturation temperature of the second area; and calculating the thermal protection factor of a thermal protection material by dividing the first energy by the second energy or dividing the difference between the first energy and the second energy by the first energy.

Abstract: Provided is a system and method for evaluating laser treatment, for converting the attribute of a laser beam and numerically evaluating proficiency of a laser treatment operator by processing data obtained by photographing the converted laser beam so as to use the evaluated data as training data. The laser treatment evaluating system includes an attenuation unit for attenuating intensity of a laser beam transmitted through a transmissive plate, a camera for photographing the laser beam transmitted through the attenuation unit, and an image data processing apparatus connected to the camera, for processing an image captured by the camera, tracking a trajectory of a laser beam on the transmissive plate, and calculating a distribution state of spots on which the laser beam on the transmissive plate is emitted.

Abstract: The present invention relates to a novel TRPV1 inhibitory peptide and a composition for skin-aging prevention and wrinkle improvement comprising the same as an active ingredient. The TRPV1 inhibitory peptide of the present invention inhibits the expressions of MMP and proinflammatory cytokines induced by UV exposure and reduces skinfold thickness and intracellular Ca2+ so that it can be effectively used as an active ingredient of the composition for skin-aging prevention, wrinkle improvement, skin-whitening, or alleviating inflammation, irritation, or pain.

Abstract: TRPV1 inhibitory peptide and a composition thereof for skin-aging prevention, wrinkle improvement, skin-whitening, or alleviating inflammation, irritation or pain is described, where the TRPV1 inhibitory peptide inhibits the expressions of MMP and proinflammatory cytokines induced by UV exposure and reduces skinfold thickness and intracellular Ca2+influx.

Abstract: The invention provides a method for treating an inflammatory skin disease in a subject comprising administering to the subject an amount of composition comprising willow tree extract as an active ingredient effective to treat the inflammatory skin disease.

Abstract: The present invention relates to a method for calculating a thermal protection factor, wherein the method comprises the steps of: applying heat to a first area coated with a thermal protection material, and a second area not coated with the thermal protection material; measuring the respective saturation temperatures of the first area and second area; calculating a first energy by dividing the energy corresponding to the heat applied to the first area by the saturation temperature of the first area; calculating a second energy by dividing the energy corresponding to the heat applied to the second area by the saturation temperature of the second area; and calculating the thermal protection factor of a thermal protection material by dividing the first energy by the second energy or dividing the difference between the first energy and the second energy by the first energy.

Abstract: The present invention relates to a composition for improving inflammatory disease, and more specifically to a composition for improving inflammatory disease able to improve inflammatory reactions and the barrier function of epithelial tissue such as the skin, to enhance aging resistance and skin elasticity and to prevent or treat aging.

Abstract: The present invention relates to a method for screening skin aging-specific genes and a method for screening anti-aging materials by controlling the expression of the genes. The invention can provide a new material having an effect on the prevention of skin aging and the treatment of skin diseases by obtaining new target genes related to skin aging and controlling the expression of the genes.

Abstract: The present invention relates to a novel TRPV1 inhibitory peptide and a composition for skin-aging prevention and wrinkle improvement comprising the same as an active ingredient. The TRPV1 inhibitory peptide of the present invention inhibits the expressions of MMP and proinflammatory cytokines induced by UV exposure and reduces skinfold thickness and intracellular Ca2+ so that it can be effectively used as an active ingredient of the composition for skin-aging prevention, wrinkle improvement, skin-whitening, or alleviating inflammation, irritation, or pain.

Abstract: The present invention discloses a laser emission system comprising a laser emission device for irradiation a laser to an area of a targeted object; a monitoring device; a display unit for displaying an image captured by the monitoring device; and a control unit connected to the monitoring device and the display unit. Here, the control unit receives the information on a movement direction and a moving distance of the laser emission device and distinguishes between an area emitted with a laser by the laser emission device and an area which is not emitted with a laser, and then displays them on the display unit. Regardless of the perceived skill of the operator, the present invention prevents the irradiation of the area from being omitted and prevents the area from being excessively or insufficiently emitted in the laser treatment.

Abstract: The present invention relates to a composition for improving inflammatory disease, and more specifically to a composition for improving inflammatory disease able to improve inflammatory reactions and the barrier function of epithelial tissue such as the skin, to enhance aging resistance and skin elasticity and to prevent or treat aging.

Abstract: The present invention relates to a method for controlling elasticity of skin and compositions for the same, and more particularly, to a method for controlling elasticity of skin comprising the step of using a compound that inhibits or induces expression of tropoelastin mRNA or protein in keratinocytes. The present invention provides compositions for maintaining elasticity of skin by controlling tropoelastin mRNA or protein within human skin. The method for controlling elasticity of skin and compositions thereof regulates tropoelastin expression in keratinocytes, maintaining elasticity of skin and inhibiting production of elastotic material.