Abstract: A modified interleukin-2 (IL-2) molecule is obtained by being subjected to a modification as follows: substituting a region in an IL-2 molecule that mediates the binding of the IL-2 molecule to interleukin-2 receptor alpha (IL2R?) with a region in an interleukin-15 (IL-15) molecule that mediates the binding of the IL-15 molecule to interleukin-15 receptor alpha (IL15R?). The region in the IL-15 molecule that mediates the binding of the IL-15 molecule to the IL15R? includes 9 or more amino acid residues. Furthermore, a protein heterodimer including the modified IL-2 molecule and IL15R? (a Sushi domain) or a variant thereof is provided. The modified IL-2 molecule and/or the protein heterodimer including the modified IL-2 significantly reduce(s) an affinity of IL2R? to greatly reduce its side effects in clinical treatment and is promising drug candidate.

Abstract: A display device includes: a sensor, a display, and a processor. The processor is configured to set a primary user of the display, detect a hand of a user using the sensor, determine whether the detected hand is a hand of the primary user, based on the determination that the detected hand is the hand of the primary user, execute a first function according to a first movement of the detected hand, and control the display to display information corresponding to the first function.

Abstract: The present disclosure relates to an input/output device mounted on a vehicle having a plurality of displays, and the input/output device may include a touch panel configured to sense a touch input, a haptic module configured to generate a tactile effect on the touch panel, a communication unit configured to perform communication with any one of the displays, and a processor configured to set one or more feedback regions on the touch panel based on a screen being displayed on the display, and control the haptic module to generate a tactile effect when a touch is applied to the one or more feedback regions, wherein the one or more feedback regions vary according to the screen being displayed on the display.

Abstract: A driving system for a vehicle includes: an input unit configured to receive user input from a user; an interface configured to acquire vehicle driving information and to acquire information from one or more devices provided in the vehicle; at least one processor; and a computer-readable medium having stored thereon instructions which, when executed by the at least one processor, causes the at least one processor to perform operations including: acquiring information from the one or more devices; determining that the vehicle is to be autonomously driven in absence of a set destination; determining at least one of a first time period or a first distance based on the acquired information; identifying a first area based on at least one of the first time period or the first distance; and providing a control signal configured to autonomously drive the vehicle within the first area.

Abstract: The present disclosure relates to a vehicle control device for a vehicle having a voice input unit, an audio output unit, and a display. The vehicle control device may include a communication unit configured to communicate with at least one of the voice input unit, the audio output unit, and the display, and a processor configured to control the communication unit to output a message for inducing an utterance of a passenger aboard the vehicle in at least one of an auditory manner and a visual manner when a preset event occurs, and identify the passenger based on receiving a response of the passenger to the message through the voice input unit, and perform a different function based on the identified passenger.

Abstract: The present disclosure relates to an input/output device mounted on a vehicle having a plurality of displays, and the input/output device may include a touch panel configured to sense a touch input, a haptic module configured to generate a tactile effect on the touch panel, a communication unit configured to perform communication with any one of the displays, and a processor configured to set one or more feedback regions on the touch panel based on a screen being displayed on the display, and control the haptic module to generate a tactile effect when a touch is applied to the one or more feedback regions, wherein the one or more feedback regions vary according to the screen being displayed on the display.

Abstract: The present disclosure relates to a vehicle control device for a vehicle having a voice input unit, an audio output unit, and a display. The vehicle control device may include a communication unit configured to communicate with at least one of the voice input unit, the audio output unit, and the display, and a processor configured to control the communication unit to output a message for inducing an utterance of a passenger aboard the vehicle in at least one of an auditory manner and a visual manner when a preset event occurs, and identify the passenger based on receiving a response of the passenger to the message through the voice input unit, and perform a different function based on the identified passenger.

Abstract: A driving system for a vehicle includes: an input unit configured to receive user input from a user; an interface configured to acquire vehicle driving information and to acquire information from one or more devices provided in the vehicle; at least one processor; and a computer-readable medium having stored thereon instructions which, when executed by the at least one processor, causes the at least one processor to perform operations including: acquiring information from the one or more devices; determining that the vehicle is to be autonomously driven in absence of a set destination; determining at least one of a first time period or a first distance based on the acquired information; identifying a first area based on at least one of the first time period or the first distance; and providing a control signal configured to autonomously drive the vehicle within the first area.

Abstract: A driver assistance apparatus in a vehicle, the driving assistance apparatus including a sensor unit configured to sense a surrounding of the vehicle; an alarm unit on the vehicle configured to output an alarm outside of the vehicle; a transceiver configured to provide wireless communication; and a processor configured to detect a person included in the sensed surrounding of the vehicle is in an alarm situation, control the transceiver to transmit an alarm signal to a mobile terminal of the person to inform the person he or she is in the alarm situation in response to a successful attempt to communicate with the mobile terminal of the person, and output an alarm via the alarm unit towards the person to inform the person he or she is in the alarm situation in response to an unsuccessful attempt to communicate with the mobile terminal of the person.

Abstract: A driver assistance apparatus in a vehicle, the driving assistance apparatus including a sensor unit configured to sense a surrounding of the vehicle; an alarm unit on the vehicle configured to output an alarm outside of the vehicle; a transceiver configured to provide wireless communication; and a processor configured to detect a person included in the sensed surrounding of the vehicle is in an alarm situation, control the transceiver to transmit an alarm signal to a mobile terminal of the person to inform the person he or she is in the alarm situation in response to a successful attempt to communicate with the mobile terminal of the person, and output an alarm via the alarm unit towards the person to inform the person he or she is in the alarm situation in response to an unsuccessful attempt to communicate with the mobile terminal of the person.

Abstract: A cover for an airbag device, which includes: a cover portion configured to cover an airbag in a folded state; a hollow insertion portion configured to be inserted into an attachment hole on the vehicle; a locking portion inserted into the attachment hole together with the insertion portion and locked at the vehicle; and a connecting portion provided inside the insertion portion and connecting inner surfaces of the insertion portion with each other so as to reinforce the insertion portion. The cover portion, the insertion portion, the locking portion, and the connecting portion are integrally formed, and the connecting portion is present at least at a position closer to a distal end side of the insertion portion in an insertion direction than the position of the attachment hole when the locking portion is locked.

Abstract: A cover used for an airbag device capable of accurately and easily adjusting a deployment direction of an airbag during a side collision according to a deployment position. The cover includes a protecting portion formed along a rolled airbag, and a plurality of attachment portions formed so as to be attached to a body of a vehicle. The protecting portion includes a slit capable of controlling the deployment direction of the airbag by changing a position through which the tab passes toward the body of the vehicle in a rolling direction of the airbag.

Abstract: A cover for an airbag device, which includes: a cover portion configured to cover an airbag in a folded state; a hollow insertion portion configured to be inserted into an attachment hole on the vehicle; a locking portion inserted into the attachment hole together with the insertion portion and locked at the vehicle; and a connecting portion provided inside the insertion portion and connecting inner surfaces of the insertion portion with each other so as to reinforce the insertion portion. The cover portion, the insertion portion, the locking portion, and the connecting portion are integrally formed, and the connecting portion is present at least at a position closer to a distal end side of the insertion portion in an insertion direction than the position of the attachment hole when the locking portion is locked.

Abstract: A cover used for an airbag device capable of accurately and easily adjusting a deployment direction of an airbag during a side collision according to a deployment position. The cover includes a protecting portion formed along a rolled airbag, and a plurality of attachment portions formed so as to be attached to a body of a vehicle. The protecting portion includes a slit capable of controlling the deployment direction of the airbag by changing a position through which the tab passes toward the body of the vehicle in a rolling direction of the airbag.

Abstract: The invention is related to a recombinant single-chain tri-specific antibody made from anti-Tumor Associated Antigen (TAA) antibody, FC interlinker, anti-CD3 antibody, HSA interlinker and anti-CD28 antibody in turn. Particularly, the invention relates to an anti-CEA, anti-CD3, anti-CD28 recombinant single-chain tri-specific antibody, CEA-scTsAb, which was constructed with three tandem antibody fragments (anti-CEA scFv, anti-CD3 scFv and anti-CD28 single-domain antibody) linked by two interlinkers (FC interlinker, HSA interlinker), and could be appended by C myc tag or histidine tag ((His)6-tag) at the C terminal. It also concerns a method for construction, expression and purification of the antibody. It also offers the encoded DNA sequence of the antibody, expression vectors and host cells for the vectors.