Abstract: A recombinant adeno-associated virus for the treatment of inflammatory diseases, and a construction method and a use thereof are provided. The recombinant adeno-associated virus uses an adeno-associated virus as a vector and contains one or more copies of a functional DNA fragment DMP-miR533. The functional DNA fragment DMP-miR533 is composed of two functional elements DMP and miR533. The DMP is an NF-?B specific promoter, and the miR533 is a microRNA that targets an NF-?B mRNA. The rAAV-DMP-miR533 of the present disclosure has a good therapeutic effect on acute colitis induced by sodium dextran sulfate, psoriasis induced by imiquimod, and arthritis induced by collagen in mice, and has good safety in the treatment of these inflammatory model mice. The rAAV-DMP-miR533 is expected to provide a new technology and new agent for the treatment of various inflammatory diseases.

Abstract: The present disclosure provides an electrochemical testing device, including: a working platform mounted with a mechanical arm, a test piece tray, a cup cover bracket and an electrochemical testing assembly. The electrochemical testing assembly includes a solution cup including a liquid through hole at a bottom, a reference electrode, an auxiliary electrode, a working electrode test piece, a test piece pallet and a columnar copper wire. The columnar copper wire lifts up the working electrode test piece to press and seal it on the liquid through hole. A cup cover of the solution cup is on the cup cover bracket, attached with the reference electrode and the auxiliary electrode. The mechanical arm injects and suctions a test solution, and transfers the working electrode test piece between the test piece tray and the test piece pallet and/or transfers the cup cover between the cup cover bracket and the solution cup.

Abstract: The present disclosure discloses a process for evaluating a corrosion inhibitor based on a high-throughput corrosion chip. In the present disclosure, a high-throughput corrosion chip is first prepared by using a chip spotter, and only a corrosion inhibitor and a corrosive substance need to be spotted on a metal sample to quickly, efficiently, and accurately evaluate performance of a corrosion inhibitor formulation, to meet corrosion test conditions such as different substances, different concentrations, and different corrosion duration; and then a corrosion degree of each measurement point in the high-throughput corrosion chip is identified and quantified by using a laser scanning confocal microscope. The high-throughput corrosion chip prepared by using the foregoing method can bear 10-1000 measurement points, and these measurement points can reflect corrosion effects of different inhibitor formulations in different corrosion duration.

Abstract: Disclosed are a superhydrophobic coating with abrasion resistance and a preparation method thereof. The coating has a composite structure formed by a nanohybrid composed of nano-SiO2 and multi-wallet carbon nanotubes, and a resin as a matrix.

Abstract: The present disclosure discloses a process for evaluating a corrosion inhibitor based on a high-throughput corrosion chip. In the present disclosure, a high-throughput corrosion chip is first prepared by using a chip spotter, and only a corrosion inhibitor and a corrosive substance need to be spotted on a metal sample to quickly, efficiently, and accurately evaluate performance of a corrosion inhibitor formulation, to meet corrosion test conditions such as different substances, different concentrations, and different corrosion duration; and then a corrosion degree of each measurement point in the high-throughput corrosion chip is identified and quantified by using a laser scanning confocal microscope. The high-throughput corrosion chip prepared by using the foregoing method can bear 10-1000 measurement points, and these measurement points can reflect corrosion effects of different inhibitor formulations in different corrosion duration.

Abstract: Disclosed in the present invention are a gene interference vector- and iron nanoparticle-based composition for killing cancer cells, and the use thereof. The composition comprises a gene interference vector and iron nanoparticles, wherein the gene interference vector is a CRISPR/Cas13a expression vector or microRNA expression vector controlled by a cancer cell specific promoter DMP, with the Cas13a-gRNA or microRNA expressed by the vector being able to inhibit, in a targeted manner, intracellular iron metabolism and the expression of reactive oxygen related genes, and the iron nanoparticles can be degraded after entering cells to produce iron ions and to increase the reactive oxygen level. The composition comprising the gene interference vector and the iron nanoparticles of the present invention can be used for preparing a new reagent for treating cancers.

Abstract: Disclosed are a superhydrophobic coating with abrasion resistance and a preparation method thereof. The coating has a composite structure formed by a nanohybrid composed of nano-SiO2 and multi-wallet carbon nanotubes, and a resin as a matrix.