Patents by Inventor Jinki Hadano

Jinki Hadano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTIBODY FOR NEUTRALIZING SUBSTANCE HAVING COAGULATION FACTOR VIII (F.VIII) FUNCTION-SUBSTITUTING ACTIVITY
    Publication number: 20230183376
    Abstract: Production was attempted for antibodies that neutralize the activity of a bispecific antibody having F.VIII function-substituting activity, for use in a method for measuring the reactivity of F.VIII in the presence of a bispecific antibody having F.VIII function-substituting activity. As a result, it was discovered that by using the produced antibodies, F.VIII activity in the plasma of a hemophilia A patient can be evaluated accurately by performing APTT-based one-stage clotting assay on a wide range of bispecific antibodies having F.VIII function-substituting activity. It was also discovered that F.VIII inhibitor titer in the plasma of a hemophilia A patient carrying F.VIII inhibitor can be evaluated accurately by APTT-based Bethesda assay.
    Type: Application
    Filed: May 21, 2021
    Publication date: June 15, 2023
    Applicant: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Tetsuhiro Soeda, Jinki Hadano