Patents by Inventor Jinming Gu

Jinming Gu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210101984
    Abstract: A B7-H3 antibody, an antigen-binding fragment thereof and a medical use thereof are provided. Furthermore, a pharmaceutical composition containing the B7-H3 antibody or antigen-binding fragment thereof, and the use thereof as a medicament are provided. In particular, a use of a human B7-H3 antibody or antigen-binding fragment thereof for the manufacture of a medicament for the treatment of a B7-H3-associated disease or condition are described.
    Type: Application
    Filed: December 15, 2020
    Publication date: April 8, 2021
    Inventors: Jinming GU, Xiaohua WANG, Xin YE, Liuqing YANG, Ting ZHANG, Weikang TAO, Lianshan ZHANG
  • Patent number: 10899837
    Abstract: A B7-H3 antibody, an antigen-binding fragment thereof and a medical use thereof are provided. Furthermore, a pharmaceutical composition containing the B7-H3 antibody or antigen-binding fragment thereof, and the use thereof as a medicament are provided. In particular, a use of a human B7-H3 antibody or antigen-binding fragment thereof for the manufacture of a medicament for the treatment of a B7-H3-associated disease or condition are described.
    Type: Grant
    Filed: March 30, 2018
    Date of Patent: January 26, 2021
    Assignees: Jiangsu Hengrui Medicine Co., Ltd., Shanghai Hengrui Pharmaceutical Co., Ltd.
    Inventors: Jinming Gu, Xiaohua Wang, Xin Ye, Liuqing Yang, Ting Zhang, Weikang Tao, Lianshan Zhang
  • Publication number: 20200339692
    Abstract: A novel PD-L1 antibody, an antigen-binding fragment thereof, and a pharmaceutical use thereof. A humanized antibody comprising a CDR of the PD-L1 antibody, a pharmaceutical composition comprising the PD-L1 antibody and the antigen-binding fragment thereof and a use of the PD-L1 antibody as a drug. A use of a humanized PD-L1 antibody in preparing a drug for treating diseases or disorders associated with PD-L1.
    Type: Application
    Filed: January 9, 2019
    Publication date: October 29, 2020
    Applicants: JIANGSU HENGRUI MEDICINE CO., LTD., SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD.
    Inventors: Xiaoling GU, Jiahua JIANG, Lei ZHANG, Qiyue HU, Jinming GU, Weikang TAO
  • Publication number: 20200157180
    Abstract: The present invention provides a fusion protein containing TGF-? receptor and pharmaceutical use thereof. Further, the present invention provides a bifunctional fusion protein comprising the PD-L1 antibody targeting portion and the TGF-?RII extracellular domain, and a pharmaceutical composition comprising the fusion protein containing TGF-? receptor, and the use thereof in the preparation of anti-cancer drug.
    Type: Application
    Filed: May 11, 2018
    Publication date: May 21, 2020
    Inventors: Jinming GU, Xiao LUO, Weikang TAO
  • Publication number: 20200031934
    Abstract: A B7-H3 antibody, an antigen-binding fragment thereof and a medical use thereof are provided. Furthermore, a pharmaceutical composition containing the B7-H3 antibody or antigen-binding fragment thereof, and the use thereof as a medicament are provided. In particular, a use of a human B7-H3 antibody or antigen-binding fragment thereof for the manufacture of a medicament for the treatment of a B7-H3-associated disease or condition are described.
    Type: Application
    Filed: March 30, 2018
    Publication date: January 30, 2020
    Inventors: Jinming GU, Xiaohua WANG, Xin YE, Liuqing YANG, Ting ZHANG, Weikang TAO, Lianshan ZHANG
  • Patent number: 8730230
    Abstract: The present invention provides an image/graphics data display mechanism for continuously displaying image/graphics data on multiple display devices of a computer that contains a system memory directly accessed by the computer's CPU during the CPU's power saving non-responding period, wherein there is provided sufficient system bandwidth, the mechanism of the present invention is independent on the resolution running on each display device and the number of display devices connected to the computer system. The mechanism provides two approaches to achieve continuous display of image/graphics data on multiple display devices computer system. In the first approach, a common clock source is used to coordinate display device horizontal synchronization signals, vertical synchronization signals, horizontal blank periods, and vertical blank periods. In the second approach, the mechanism has a control on the lengths and occurrences of the display device blank periods.
    Type: Grant
    Filed: August 12, 2003
    Date of Patent: May 20, 2014
    Assignee: VIA Technologies, Inc.
    Inventors: Yi-Fang Michael Shiuan, Xinwei Yang, Jinming Gu, Iming Pai
  • Patent number: 8681205
    Abstract: An interface unit is described that comprises a buffer for storing captured video data generated by a three dimensional (3D) device intended for a 3D monitor. The interface unit further comprises a synchronization signal extractor configured to extract vertical synchronization (vsync) signals from the video data and a control signal unit configured to derive control signals for a viewing device based on the stored vsync signals. The interface unit transmits the control signals to the viewing device.
    Type: Grant
    Filed: April 13, 2011
    Date of Patent: March 25, 2014
    Assignee: Via Technologies, Inc.
    Inventors: Iming Pai, Jinming Gu, Xinwei Yang
  • Publication number: 20110310223
    Abstract: An interface unit is described that comprises a buffer for storing captured video data generated by a three dimensional (3D) device intended for a 3D monitor. The interface unit further comprises a synchronization signal extractor configured to extract vertical synchronization (vsync) signals from the video data and a control signal unit configured to derive control signals for a viewing device based on the stored vsync signals. The interface unit transmits the control signals to the viewing device.
    Type: Application
    Filed: April 13, 2011
    Publication date: December 22, 2011
    Applicant: VIA TECHNOLOGIES, INC.
    Inventors: Iming Pai, Jinming Gu, Xinwei Yang
  • Publication number: 20110275697
    Abstract: The present invention provides methods for modulating the level or activity of cyclin D by inhibiting EGLN2 expression or activity. The methods are particularly useful for treating or preventing a disorder associated with elevated cyclin D levels or activity, such as cancer.
    Type: Application
    Filed: February 12, 2009
    Publication date: November 10, 2011
    Applicant: DANA FARBER CANCER INSTITUTE, INC.
    Inventors: William G. Kaelin, JR., Archana Bommi-Reddy, Jinming Gu
  • Patent number: 7897741
    Abstract: The present invention relates to polypeptide and nucleic acids constructs which are useful for determining the cell cycle status of a mammalian cell. Host cells transfected with these nucleic acid constructs can be used to determine the effects that test agents have upon the mammalian cell cycle.
    Type: Grant
    Filed: September 16, 2009
    Date of Patent: March 1, 2011
    Assignee: GE Healthcare UK Limited
    Inventors: Suzanne Hancock, Simon Stubbs, Nicholas Thomas, Ellen Fanning, Jinming Gu
  • Patent number: 7745123
    Abstract: The present invention relates to non-destructive and dynamic means for determining the cell cycle position of living cells. The invention provides stable cell lines which can be used to determine the cell cycle position, together with methods for measuring the effect of a test agent on the cell cycle position.
    Type: Grant
    Filed: July 22, 2005
    Date of Patent: June 29, 2010
    Assignees: GE Healthcare UK Limited, Vanderbilt University
    Inventors: Suzanne Hancock, Simon Stubbs, Nicholas Thomas, Ellen Fanning, Jinming Gu
  • Publication number: 20100028899
    Abstract: The present invention relates to polypeptide and nucleic acids constructs which are useful for determining the cell cycle status of a mammalian cell. Host cells transfected with these nucleic acid constructs can be used to determine the effects that test agents have upon the mammalian cell cycle.
    Type: Application
    Filed: September 16, 2009
    Publication date: February 4, 2010
    Applicant: GE HEALTHCARE UK LIMITED
    Inventors: Suzanne Hancock, Simon Stubbs, Nicholas Thomas, Ellen Fanning, Jinming Gu
  • Patent number: 7612189
    Abstract: The present invention relates to polypeptide and nucleic acids constructs which are useful for determining the cell cycle status of a mammalian cell. Host cells transfected with these nucleic acid constructs can be used to determine the effects that test agents have upon the mammalian cell cycle.
    Type: Grant
    Filed: July 22, 2005
    Date of Patent: November 3, 2009
    Assignees: GE Healthcare UK Limited, Vanderbilt University
    Inventors: Suzanne Hancock, Simon Stubbs, Nicholas Thomas, Ellen Fanning, Jinming Gu
  • Publication number: 20070264681
    Abstract: The present invention relates to polypeptide and nucleic acids constructs which are useful for determining the cell cycle status of a mammalian cell. Host cells transfected with these nucleic acid constructs can be used to determine the effects that test agents have upon the mammalian cell cycle.
    Type: Application
    Filed: July 22, 2005
    Publication date: November 15, 2007
    Applicants: GE HEALTHCARE UK LIMITED, VANDERBILT UNIVERSITY
    Inventors: Suzanne Hancock, Simon Stubbs, Nicholas Thomas, Ellen Fanning, Jinming Gu
  • Publication number: 20070238144
    Abstract: The present invention relates to non-destructive and dynamic means for determining the cell cycle position of living cells. The invention provides stable cell lines which can be used to determine the cell cycle position, together with methods for measuring the effect of a test agent on the cell cycle position.
    Type: Application
    Filed: July 22, 2005
    Publication date: October 11, 2007
    Applicants: GE HEALTHCARE UK LIMITED, VANDERBILT UNIVERSITY
    Inventors: Suzanne Hancock, Simon Stubbs, Nicholas Thomas, Ellen Fanning, Jinming Gu
  • Publication number: 20070212707
    Abstract: The present invention relates to nucleic acid reporter constructs and host cells transfected with said constructs. The invention also relates to methods which are useful for determining the cell cycle status of a mammalian cell and for determining the effect of a test agent on the cell cycle position of a mammalian cell.
    Type: Application
    Filed: July 22, 2005
    Publication date: September 13, 2007
    Applicants: GE HEALTHCARE UK LIMITED, VANDERBILT UNIVERSITY
    Inventors: Suzanne Hancock, Simon Stubbs, Nicholas Thomas, Ellen Fanning, Jinming Gu
  • Patent number: 7245272
    Abstract: The present invention provides an image/graphics data display mechanism for continuously displaying image/graphics data on dual display devices of a computer that contains a Display FIFO and a system memory directly accessed by the computer's CPU, wherein at least one of the display devices is running in a low-resolution mode, the mechanism comprising: determining which of the display devices is running in the low-resolution mode; receiving a power saving signal from the CPU; requesting an access to the system memory, and pre-storing the image/graphics data for the low-resolution device into the Display FIFO; and triggering the CPU power saving process according to a display timing scheme of the other display device.
    Type: Grant
    Filed: August 12, 2003
    Date of Patent: July 17, 2007
    Assignee: VIA Technologies, Inc.
    Inventors: Yi-Fang Michael Shiuan, Xinwei Yang, Jinming Gu, Iming Pai
  • Patent number: 7205957
    Abstract: A mechanism is disclosed for adjusting one or more operational parameters of a component in such a way that the adjustment has minimal impact on graphics display. When a component (e.g. a processor) wishes to adjust one or more of its operational parameters (e.g. operating clock frequency), it submits a request to a graphics processing mechanism (GPM). In response, the GPM, which controls multiple displays, sends a response to the component at a proper time to cause the component to adjust the operational parameter during a time period in which a first display and a second display are both experiencing a blank period. By coordinating the timing of the adjustment in this way, it is possible to keep the size of a video memory to a minimum.
    Type: Grant
    Filed: August 18, 2003
    Date of Patent: April 17, 2007
    Assignee: Via Technologies, Inc.
    Inventors: Yi-Fang Michael Shiuan, Xinwei Yang, Jinming Gu, Iming Pai
  • Patent number: 6919899
    Abstract: An uninterrupted data display method for a computer system having a system memory directly accessed by a processor, for preventing disrupted data display from transmission break is disclosed. The method is accomplished before the processor goes into a non-responding period due to an execution of an economical process. The method includes the steps of: (i) providing a data storage device having a depth for storing a period long of data. (ii) Comparing the period of said depth to the non-responding period, if the period of said depth is longer than the non-responding period, jump to step (iii), otherwise, to step (iv). (iii) Loading the period long of data from a system memory into the data storage device then jump to step (v). (iv) Detecting a synchronization pulse then jump to step (v), wherein step (v) is to be accomplished within a non-display period, and, (v) executing the economical process.
    Type: Grant
    Filed: August 12, 2003
    Date of Patent: July 19, 2005
    Assignee: Via Technologies, Inc.
    Inventors: Yi-Fang Michael Shiuan, Xinwei Yang, Jinming Gu, Iming Pai
  • Publication number: 20050052438
    Abstract: A mechanism is disclosed for adjusting one or more operational parameters of a component in such a way that the adjustment has minimal impact on graphics display. When a component (e.g. a processor) wishes to adjust one or more of its operational parameters (e.g. operating clock frequency), it submits a request to a graphics processing mechanism (GPM). In response, the GPM, which controls multiple displays, sends a response to the component at a proper time to cause the component to adjust the operational parameter during a time period in which a first display and a second display are both experiencing a blank period. By coordinating the timing of the adjustment in this way, it is possible to keep the size of a video memory to a minimum.
    Type: Application
    Filed: August 18, 2003
    Publication date: March 10, 2005
    Inventors: Yi-Fang Shiuan, Xinwei Yang, Jinming Gu, Iming Pai