Patents by Inventor Jinping SHI

Jinping SHI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12258394
    Abstract: Provided are an IL-5 antibody, an antigen binding fragment thereof, and a medical application therefor. The present invention comprises a mouse-derived antibody containing an IL-5 antibody CDR region, a chimeric antibody, a humanized antibody, and a pharmaceutical composition comprising said IL-5 antibody and said antigen binding fragment thereof, as well as the use of the pharmaceutical composition as a drug.
    Type: Grant
    Filed: May 18, 2022
    Date of Patent: March 25, 2025
    Assignees: Jiangsu Hengrui Medicine Co., Ltd., Shanghai Hengrui Pharmaceutical Co., Ltd.
    Inventors: Hua Ying, Jinping Shi, Yifang Wang, Qiyue Hu, Hu Ge, Weikang Tao
  • Publication number: 20250043022
    Abstract: Provided are an antigen-binding molecule specifically binding to PSMA and CD3, and a pharmaceutical use thereof. The antigen-binding molecule can be used for treating tumor-related diseases.
    Type: Application
    Filed: February 7, 2023
    Publication date: February 6, 2025
    Inventors: Hua YING, Jinping SHI, Hao YANG, Xiaomin ZHANG, Xinsheng JIN, Weikang TAO
  • Patent number: 12202891
    Abstract: Disclosed are an antibody capable of binding to thymic stromal lymphopoietin and the use thereof. Disclosed are an anti-TSLP antibody, comprising a murine antibody, chimeric antibody and humanized antibody of the light chain and heavy chain variable regions of the anti-TSLP antibody and antigen-binding fragments thereof, or a pharmaceutically acceptable salt or solvent compound thereof, and the use thereof as a medicament for treating asthma, especially the use thereof in the preparation of a drug for treating TSLP-positive diseases or conditions.
    Type: Grant
    Filed: March 15, 2024
    Date of Patent: January 21, 2025
    Inventors: Jinping Shi, Hua Ying, Tingting Li, Yifang Wang, Guimei Yang, Hu Ge, Weikang Tao
  • Publication number: 20240392020
    Abstract: Provided is an antigen-binding molecule, particularly a domain-engineered antibody, wherein at least one constant region domain CH1/CL of the antibody is replaced by a Titin T-chain/Obscurin-O chain.
    Type: Application
    Filed: May 12, 2022
    Publication date: November 28, 2024
    Inventors: Hua Ying, Qiyue Hu, Xinsheng Jin, Jinping Shi, Ling Zhang, Langyong Mao, Xin Ye, Weikang Tao
  • Publication number: 20240254215
    Abstract: Disclosed are an antibody capable of binding to thymic stromal lymphopoietin and the use thereof. Disclosed are an anti-TSLP antibody, comprising a murine antibody, chimeric antibody and humanized antibody of the light chain and heavy chain variable regions of the anti-TSLP antibody and antigen-binding fragments thereof, or a pharmaceutically acceptable salt or solvent compound thereof, and the use thereof as a medicament for treating asthma, especially the use thereof in the preparation of a drug for treating TSLP-positive diseases or conditions.
    Type: Application
    Filed: March 15, 2024
    Publication date: August 1, 2024
    Inventors: Jinping SHI, Hua YING, Tingting LI, Yifang WANG, Guimei YANG, Hu GE, Weikang TAO
  • Publication number: 20230120270
    Abstract: The present disclosure relates to a new polypeptide complex. Specifically, the present disclosure relates to a domain engineered antibody. At least one of the constant region domains CH1 and/or CL of the antibody is replaced, and the domain CH1/CL is replaced by a Titin T chain/Obscurin-O chain or by a Titin T chain/Obscurin-like-O chain.
    Type: Application
    Filed: January 8, 2021
    Publication date: April 20, 2023
    Inventors: Hua YING, Qiyue HU, Ling ZHANG, Langyong MAO, Jinping SHI, Tingting LI, Weiming LAI, Qianshan QIN, Xinsheng JIN, Weikang TAO
  • Publication number: 20220356239
    Abstract: Provided are an IL-5 antibody, an antigen binding fragment thereof, and a medical application therefor. The present invention comprises a mouse-derived antibody containing an IL-5 antibody CDR region, a chimeric antibody, a humanized antibody, and a pharmaceutical composition comprising said IL-5 antibody and said antigen binding fragment thereof, as well as the use of the pharmaceutical composition as a drug.
    Type: Application
    Filed: May 18, 2022
    Publication date: November 10, 2022
    Inventors: Hua Ying, Jinping Shi, Yifang Wang, Qiyue Hu, Hu Ge, Weikang Tao
  • Publication number: 20220340654
    Abstract: Disclosed are an antibody capable of binding to thymic stromal lymphopoietin and the use thereof. Disclosed are an anti-TSLP antibody, comprising a murine antibody, chimeric antibody and humanized antibody of the light chain and heavy chain variable regions of the anti-TSLP antibody and antigen-binding fragments thereof, or a pharmaceutically acceptable salt or solvent compound thereof, and the use thereof as a medicament for treating asthma, especially the use thereof in the preparation of a drug for treating TSLP-positive diseases or conditions.
    Type: Application
    Filed: June 3, 2020
    Publication date: October 27, 2022
    Inventors: Jinping SHI, Hua YING, Tingting LI, Yifang WANG, Guimei YANG, Hu GE, Weikang TAO
  • Patent number: 11365247
    Abstract: Provided are an IL-5 antibody, an antigen binding fragment thereof, and a medical application therefor. The present invention comprises a mouse-derived antibody containing an IL-5 antibody CDR region, a chimeric antibody, a humanized antibody, and a pharmaceutical composition comprising said IL-5 antibody and said antigen binding fragment thereof, as well as the use of the pharmaceutical composition as a drug.
    Type: Grant
    Filed: September 28, 2018
    Date of Patent: June 21, 2022
    Assignees: Jiangsu Hengrui Medicine Co., Ltd., Shanghai Hengrui Pharmaceutical Co., Ltd.
    Inventors: Hua Ying, Jinping Shi, Yifang Wang, Qiyue Hu, Hu Ge, Weikang Tao
  • Publication number: 20220185875
    Abstract: The present disclosure provides a bispecific antibody specifically bound to VEGF and ANG2, comprising an anti-VEGF antibody or antigen-binding fragment thereof that specifically binds to VEGF, and an anti-ANG2 single-domain antibody that specifically binds to ANG2, wherein the anti-ANG2 single domain antibody is directly or indirectly connected to the anti-VEGF antibody or an antigen-binding fragment thereof. The present disclosure further provides an anti-ANG2 single domain antibody and an antigen-binding fragment thereof, as well as a preparation and application of said antibody.
    Type: Application
    Filed: March 7, 2020
    Publication date: June 16, 2022
    Inventors: Hua YING, Jinping SHI, Langyong MAO, Hu GE, Xiaoying YANG, Weikang TAO
  • Publication number: 20210371506
    Abstract: Murine, chimeric or humanized anti-Abeta antibody having a specific CDR region, an antigen-binding fragment thereof, a pharmaceutical composition thereof, and usage thereof. Use of a humanized anti-Abeta antibody for the preparation of drugs for the treatment of a disease or disorder (such as Alzheimer's disease) caused by amyloid beta protein.
    Type: Application
    Filed: July 16, 2019
    Publication date: December 2, 2021
    Inventors: Hua Ying, Ling Zhang, Jinping Shi, Xiaomin Zhang, Jiakang Sun, Qiyue Hu, Weikang Tao
  • Publication number: 20200262909
    Abstract: Provided are an IL-5 antibody, an antigen binding fragment thereof, and a medical application therefor. The present invention comprises a mouse-derived antibody containing an IL-5 antibody CDR region, a chimeric antibody, a humanized antibody, and a pharmaceutical composition comprising said IL-5 antibody and said antigen binding fragment thereof, as well as the use of the pharmaceutical composition as a drug.
    Type: Application
    Filed: September 28, 2018
    Publication date: August 20, 2020
    Inventors: Hua Ying, Jinping Shi, Ylfang Wang, Qiyue Hu, Hu Ge, Weikang Tao
  • Patent number: 10445397
    Abstract: According to an embodiment, a request for browsing a web page is received from a user via a browser of a mobile terminal; whether the web page comprises an input widget is determined; whether the input widget is triggered is determined if the web page comprise the input widget; input information of the user is obtained when the input widget is triggered; the input information is processed by calling a processing interface corresponding to a type of the input widget; and processed input information is uploaded.
    Type: Grant
    Filed: June 5, 2015
    Date of Patent: October 15, 2019
    Assignee: Tencent Technology (Shenzhen) Company Limited
    Inventors: Kaixiang Zhang, Jiejun Zhang, Jinping Shi
  • Publication number: 20150269274
    Abstract: According to an embodiment, a request for browsing a web page is received from a user via a browser of a mobile terminal; whether the web page comprises an input widget is determined; whether the input widget is triggered is determined if the web page comprise the input widget; input information of the user is obtained when the input widget is triggered; the input information is processed by calling a processing interface corresponding to a type of the input widget; and processed input information is uploaded.
    Type: Application
    Filed: June 5, 2015
    Publication date: September 24, 2015
    Inventors: Kaixiang ZHANG, Jiejun ZHANG, Jinping SHI