Patents by Inventor Jinq Chyi Lee

Jinq Chyi Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CDGSH iron sulfur domain 2 activators and use thereof
    Patent number: 11827629
    Abstract: Isoindoline compounds and their pharmaceutical compositions. Also provided are methods of treating a Cisd2-insufficiency associated disorder and protecting against doxorubicin-induced cardiotoxicity.
    Type: Grant
    Filed: May 25, 2022
    Date of Patent: November 28, 2023
    Assignees: National Health Research Institutes, National Yang Ming Chiao Tung University
    Inventors: Ting-Fen Tsai, Jinq-Chyi Lee, Teng-Kuang Yeh
  • METHODS OF TREATING CDGSH IRON SULFUR DOMAIN 2 INSUFFICIENCY-ASSOCIATED DISORDERS
    Publication number: 20230100367
    Abstract: A method of treating a Cisd2 insufficiency-associated disorder. The method includes administering to a subject in need a compound of formula (I). Also disclosed is a method of increasing Cisd2 gene expression.
    Type: Application
    Filed: August 24, 2022
    Publication date: March 30, 2023
    Inventors: Ting-Fen Tsai, Jinq-Chyi Lee, Hui-Yi Shiao, Chi-Hsiao Yeh
  • CDGSH IRON SULFUR DOMAIN 2 ACTIVATORS AND USE THEREOF
    Publication number: 20220411418
    Abstract: Isoindoline compounds and their pharmaceutical compositions. Also provided are methods of treating a Cisd2-insufficiency associated disorder and protecting against doxorubicin-induced cardiotoxicity.
    Type: Application
    Filed: May 25, 2022
    Publication date: December 29, 2022
    Inventors: Ting-Fen Tsai, Jinq-Chyi Lee, Teng-Kuang Yeh
  • METHOD FOR TREATING AMYLOIDOGENIC DISEASE
    Publication number: 20220152090
    Abstract: The present disclosure relates to a method for treating or preventing or delaying the onset or progression of an amyloidogenic disease in a subject in need, comprising administering a pharmaceutical composition comprising a therapeutically effective amount of amphiphilic liposaccharide to the subject. The present disclosure also relates to a method for selecting an agent for treating or preventing or delaying the onset or progression of an amyloidogenic disease and a novel liposaccharide.
    Type: Application
    Filed: November 12, 2021
    Publication date: May 19, 2022
    Inventors: Shu-Yi LIN, Jyh-Lyh JUANG, Jinq-Chyi LEE
  • Glycoside compounds
    Patent number: 8697658
    Abstract: Compounds of formula (I): wherein X, Y, and Z are defined herein. Also disclosed are pharmaceutical compositions and therapeutical methods related to these compounds.
    Type: Grant
    Filed: December 13, 2012
    Date of Patent: April 15, 2014
    Assignee: National Health Research Institutes
    Inventors: Jinq-Chyi Lee, Yu-Sheng Chao
  • Method for preparing hexose derivatives
    Patent number: 7985856
    Abstract: A method for preparing hexose derivatives comprises the steps of providing a silylated hexose, treating the silylated hexose with a first carbonyl compound in the presence of a catalyst to form an ketalized hexose, treating the ketalized hexose with a second carbonyl compound followed by treating with a first reductant to form an etherized hexose, and converting the etherized hexose into a target hexose derivative, which can be 2-alcohol hexose, 3-alcohol hexose, 4-alcohol hexose, or a 6-alcohol hexose. In particular, the present invention can prepare the hexose derivatives with highly regioselective scheme to protect individual hydroxyls of monosaccharide units and install an orthogonal protecting group pattern in a one-pot manner.
    Type: Grant
    Filed: October 18, 2007
    Date of Patent: July 26, 2011
    Assignee: National Tsing Hua University
    Inventors: Shang-Cheng Hung, Cheng-Chung Wang, Jinq Chyi Lee, Shun Yuan Luo, Suvarn Subhash Kulkarni, Yu Wen Huang, Chia Chen Lee, Ken Lien Chang