Patents by Inventor Jinqing Zhong

Jinqing Zhong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing AD-35
    Patent number: 10399992
    Abstract: Disclosed are a method for preparing a benzodioxole derivative (AD-35) shown by Formula (I) and an intermediate thereof. The method of the present invention involves: using piperic acid as a raw material; and performing bromination, esterification, cyanidation, cyclopropane lactamization, amide nitrogen alkylation, deprotection, piperidine nitrogen alkylation and salification to obtain the compound of Formula (I). The method has cheap and easily available start raw materials, short synthesis routes and simple operation, and is suitable for industrial production.
    Type: Grant
    Filed: March 28, 2017
    Date of Patent: September 3, 2019
    Assignee: Zhejiang Hisun Pharmaceutical Co., Ltd.
    Inventors: Jinqing Zhong, Xuyang Zhao, Hua Bai, Yongxiang Gong, Xinlong Zhang, Qifeng Zhu, Weiwei Liu, Ya Zhou
  • Process For Preparing AD-35
    Publication number: 20190100527
    Abstract: Disclosed are a method for preparing a benzodioxole derivative (AD-35) shown by Formula (I) and an intermediate thereof. The method of the present invention involves: using piperic acid as a raw material; and performing bromination, esterification, cyanidation, cyclopropane lactamization, amide nitrogen alkylation, deprotection, piperidine nitrogen alkylation and salification to obtain the compound of Formula (I). The method has cheap and easily available start raw materials, short synthesis routes and simple operation, and is suitable for industrial production.
    Type: Application
    Filed: March 28, 2017
    Publication date: April 4, 2019
    Applicant: Zhejiang Hisun Pharmaceutical Co., Ltd.
    Inventors: Jinqing Zhong, Xuyang Zhao, Hua Bai, Yongxiang Gong, Xinlong Zhang, Qifeng Zhu, Weiwei Liu, Ya Zhou
  • Benzodioxole derivative and preparation method and use thereof
    Patent number: 9346818
    Abstract: Provided in the present invention are novel benzodioxole derivatives and preparation methods thereof. These compounds represented by formula (I) or pharmaceutically acceptable salts thereof have acetylcholinesterase inhibitory activity, so can be used in the treatment or prevention of Alzheimer's disease. The definitions of R1, R2 and A of formula (I) can be seen in the description.
    Type: Grant
    Filed: July 3, 2013
    Date of Patent: May 24, 2016
    Assignee: Zhejiang Hisun Pharmaceutical Co., Ltd.
    Inventors: Hua Bai, Xuyang Zhao, Jinqing Zhong, Yongxiang Gong, Qifeng Zhu, Xiaoyu Liu, Xiaohe Zheng, Lifei Liu
  • BENZODIOXOLE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF
    Publication number: 20150191480
    Abstract: Provided in the present invention are novel benzodioxole derivatives and preparation methods thereof. These compounds represented by formula (I) or pharmaceutically acceptable salts thereof have acetylcholinesterase inhibitory activity, so can be used in the treatment or prevention of Alzheimer's disease. The definitions of R1, R2 and A of formula (I) can be seen in the description.
    Type: Application
    Filed: July 3, 2013
    Publication date: July 9, 2015
    Applicant: ZHEJIANG HISUN PHARMACEUTICAL CO., LTD.
    Inventors: Hua Bai, Xuyang Zhao, Jinqing Zhong, Yongxiang Gong, Qifeng Zhu, Xiaoyu Liu, Xiaohe Zheng, Lifei Liu
  • Benzamide derivative with anticancer activity and preparation method and use thereof
    Patent number: 8946478
    Abstract: Provided are a benzamide derivative as shown in formula (I) or a pharmaceutically acceptable salt thereof, and the preparation method and use thereof for preparing a medicine for treating cancer, wherein the group definitions of formula (I) are as set out in the description.
    Type: Grant
    Filed: November 3, 2011
    Date of Patent: February 3, 2015
    Assignee: Zhejiang Hisun Pharmaceutical Co., Ltd.
    Inventors: Hua Bai, Xuyang Zhao, Yongxiang Gong, Jinqing Zhong, Qifeng Zhu, Xiaoyu Liu, Lifei Liu, Qixian Zhou
  • BENZAMIDE DERIVATIVE WITH ANTICANCER ACTIVITY AND PREPARATION METHOD AND USE THEREOF
    Publication number: 20130225810
    Abstract: Provided are a benzamide derivative as shown in formula (I) or a pharmaceutically acceptable salt thereof, and the preparation method and use thereof for preparing a medicine for treating cancer, wherein the group definitions of formula (I) are as set out in the description.
    Type: Application
    Filed: November 3, 2011
    Publication date: August 29, 2013
    Applicant: Zhejiang Hisun Pharmaceutical Co., Ltd.
    Inventors: Hua Bai, Xuyang Zhao, Yongxiang Gong, Jinqing Zhong, Qifeng Zhu, Xiaoyu Liu, Lifei Liu, Qixian Zhou