Patents by Inventor Jinquan Luo

Jinquan Luo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240124583
    Abstract: Embodiments of the present invention provide isolated proteins comprising antigen binding domains that bind kallikrein related peptidase 2 (hK2), including monospecific and bispecific antibodies. Additional embodiments of the invention provide polynucleotides encoding the hk2-specific proteins, vectors, host cells, and methods of making and using them.
    Type: Application
    Filed: December 27, 2023
    Publication date: April 18, 2024
    Inventors: Rajkumar Ganesan, John Lee, Jinquan Luo, Theresa McDevitt, Fei Shen, Degang Song, Raymond Brittingham, Sathyadevi Venkataramani, Sanjaya Singh, Yonghong Zhao, Fang Yi, Sherry Lynn LaPorte
  • Publication number: 20240067754
    Abstract: Disclosed are materials and methods for improved single chain variable fragments.
    Type: Application
    Filed: September 5, 2023
    Publication date: February 29, 2024
    Inventors: Jinquan LUO, Lauren BOUCHER, Michael FELDKAMP, Michael DIEM, Anthony A. ARMSTRONG, Alexey TEPLYAKOV, Chichi HUANG
  • Publication number: 20240050546
    Abstract: The present disclosure relates to Staphylococcus aureus leukocidin A (LukA) and leukocidin B (LukB) variant polypeptides, and polynucleotides encoding the LukA, LukB and LukAB variant polypeptides. The present disclosure further relates to vaccine compositions comprising these LukA and LukB variants, and methods of generating an immune response against Staphylococcus aureus in a subject.
    Type: Application
    Filed: September 28, 2021
    Publication date: February 15, 2024
    Inventors: Brian MORROW, Sergey KONSTANTINOV, Jeroen GEURTSEN, Jinquan LUO, Sandeep SOMANI, Peter T. BUCKLEY, Victor J. TORRES
  • Publication number: 20230340155
    Abstract: Antibodies that specifically bind PD-1 or antigen binding fragments thereof, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing are useful in the treatment of an inflammatory or immune disorder.
    Type: Application
    Filed: June 8, 2023
    Publication date: October 26, 2023
    Inventors: Qiang Chen, Suzanne Cole, Karen Duffy, Yanxia Guo, Debra Gardner, Damon Hamel, Shannon Hitchcock, Ann Lacombe, Jinquan Luo, Ravi Malaviya, Yevgeniya Orlovsky, Pejman Soroosh, Melissa Swiecki, Deepti Wilkinson
  • Patent number: 11787875
    Abstract: Disclosed are materials and methods for improved single chain variable fragments.
    Type: Grant
    Filed: August 14, 2020
    Date of Patent: October 17, 2023
    Assignee: Janssen Biotech, Inc.
    Inventors: Jinquan Luo, Lauren Boucher, Michael Feldkamp, Michael Diem, Anthony A. Armstrong, Alexey Teplyakov, Chichi Huang
  • Patent number: 11746161
    Abstract: Antibodies that specifically bind PD-1 or antigen binding fragments thereof, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing are useful in the treatment of an inflammatory or immune disorder.
    Type: Grant
    Filed: December 17, 2020
    Date of Patent: September 5, 2023
    Assignee: Janssen Biotech, Inc.
    Inventors: Qiang Chen, Suzanne Cole, Karen Duffy, Yanxia Guo, Debra Gardner, Damon Hamel, Shannon Hitchcock, Ann Lacombe, Jinquan Luo, Ravi Malaviya, Yevgeniya Orlovsky, Pejman Soroosh, Melissa Swiecki, Deepti Wilkinson
  • Publication number: 20230151083
    Abstract: Monoclonal anti-PHF-tau antibodies and antigen-binding fragments thereof are described. Also described are nucleic acids encoding the antibodies, compositions comprising the antibodies, methods of producing the antibodies and using the antibodies for treating or preventing conditions such as tauopathies.
    Type: Application
    Filed: April 7, 2021
    Publication date: May 18, 2023
    Inventors: Kristof Van Kolen, Marc Mercken, Rupesh Nanjunda, Sanjaya Singh, Sherry La Porte, Jinquan Luo, Pharavee Jaiprasart, Sathya Venkataramani, Rajkumar Ganesan
  • Publication number: 20230040715
    Abstract: The disclosure provides antigen binding domains that bind cluster of differentiation 3 (CD3) protein, comprising the antigen binding domains that bind CD3?, polynucleotides encoding them, vectors, host cells, methods of making and using them.
    Type: Application
    Filed: March 23, 2022
    Publication date: February 9, 2023
    Inventors: Adam Zwolak, Raymond Brittingham, Scott R. Brodeur, Rajkumar Ganesan, Sherry Lynn La Porte, Jinquan Luo, Fang Yi, Colleen M. Kane, Triveni K. Bhatt
  • Publication number: 20220411504
    Abstract: The disclosure provides antigen binding domains that bind cluster of differentiation 3 (CD3) protein, comprising the antigen binding domains that bind CD3?, polynucleotides encoding them, vectors, host cells, methods of making and using them.
    Type: Application
    Filed: May 26, 2021
    Publication date: December 29, 2022
    Inventors: Raymond Brittingham, Scott R. Brodeur, Rajkumar Ganesan, Jaclyn Hoover, Steven A. Jacobs, Colleen M. Kane, Jinquan Luo, Sanjaya Singh, Fang Yi, Adam Zwolak, Triveni K. Bhatt, Michael Dennis Feldkamp, Sherry Lynn La Porte
  • Publication number: 20220177560
    Abstract: The invention provides antibodies or antigen binding fragments thereof that bind to 3pE A? and methods of making and using the antibodies or antigen binding fragments thereof, including use for formulations, administration and kits. The antibody and antigen binding fragments thereof and methods disclosed are useful for diagnosis, prognosis and treatment of Alzheimer's disease or other ?-amyloid-related diseases.
    Type: Application
    Filed: March 25, 2020
    Publication date: June 9, 2022
    Inventors: Bianca Van Broeck, Marc Mercken, Wilson Edwards, Sanjaya Singh, Jinquan Luo, Sherry La Porte, Rajkumar Ganesan, Chichi Huang
  • Publication number: 20220106387
    Abstract: The invention provides antibodies or antigen binding fragments thereof that bind to 3pE A? and methods of making and using the antibodies or antigen binding fragments thereof, including use for formulations, administration and kits. The antibody and antigen binding fragments thereof and methods disclosed are useful for diagnosis, prognosis and treatment of Alzheimer's disease or other ?-amyloid-related diseases.
    Type: Application
    Filed: December 17, 2021
    Publication date: April 7, 2022
    Inventors: Bianca Van Broeck, Marc Mercken, Wilson Edwards, Sanjaya Singh, Jinquan Luo, Sherry La Porte, Rajkumar Ganesan, Chichi Huang
  • Publication number: 20220064254
    Abstract: The present disclosure provides for chimeric antigen receptors (CARs) that specifically target a human Kallikrein-2 (hK2), and immunoresponsive cells comprising such CARs, for the treatment of cancer.
    Type: Application
    Filed: July 23, 2020
    Publication date: March 3, 2022
    Inventors: Raymond BRITTINGHAM, Rajkumar GANESAN, Sherry LA PORTE, John T. LEE, Jinquan LUO, Theresa MCDEVITT, Fei SHEN, Sanjaya SINGH, Degang SONG, Sathyadevi VENKATARAMANI, Fang YI, Yonghong ZHAO
  • Publication number: 20220054634
    Abstract: An anti-IL-23 antibody, including isolated nucleic acids that encode at least one anti-IL-23 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.
    Type: Application
    Filed: November 9, 2021
    Publication date: February 24, 2022
    Inventors: Jacquelne Benson, Mark Cunningham, Cynthia Duchala, Jill Giles-Komar, Jinquan Luo, Michael Rycyzyn, Raymond Sweet
  • Patent number: 11236155
    Abstract: The invention provides antibodies or antigen binding fragments thereof that bind to 3pE A? and methods of making and using the antibodies or antigen binding fragments thereof, including use for formulations, administration and kits. The antibody and antigen binding fragments thereof and methods disclosed are useful for diagnosis, prognosis and treatment of Alzheimer's disease or other ?-amyloid-related diseases.
    Type: Grant
    Filed: March 25, 2020
    Date of Patent: February 1, 2022
    Assignee: Janssen Pharmaceutica NV
    Inventors: Bianca Van Broeck, Marc Mercken, Wilson Edwards, Sanjaya Singh, Jinquan Luo, Sherry La Porte, Rajkumar Ganesan, Chichi Huang
  • Patent number: 11185584
    Abstract: An anti-IL-23 antibody, including isolated nucleic acids that encode at least one anti-IL-23 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.
    Type: Grant
    Filed: January 17, 2020
    Date of Patent: November 30, 2021
    Assignee: Janssen Biotech, Inc.
    Inventors: Jacqueline Benson, Mark Cunningham, Cynthia Duchala, Jill Giles-Komar, Jinquan Luo, Michael Rycyzyn, Raymond Sweet
  • Patent number: 10995149
    Abstract: Antibodies that specifically bind PD-1 or antigen binding fragments thereof, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing are useful in the treatment of an inflammatory or immune disorder.
    Type: Grant
    Filed: June 4, 2018
    Date of Patent: May 4, 2021
    Assignee: Janssen Biotech, Inc.
    Inventors: Qiang Chen, Suzanne Cole, Karen Duffy, Yanxia Guo, Debra Gardner, Damon Hamel, Shannon Hitchcock, Ann Lacombe, Jinquan Luo, Ravi Malaviya, Yevgeniya Orlovsky, Pejman Soroosh, Melissa Swiecki, Deepti Wilkinson
  • Publication number: 20210102000
    Abstract: Antibodies that specifically bind PD-1 or antigen binding fragments thereof, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing are useful in the treatment of an inflammatory or immune disorder.
    Type: Application
    Filed: December 17, 2020
    Publication date: April 8, 2021
    Inventors: Qiang Chen, Suzanne Cole, Karen Duffy, Yanxia Guo, Debra Gardner, Damon Hamel, Shannon Hitchcock, Ann Lacombe, Jinquan Luo, Ravi Malaviya, Yevgeniya Orlovsky, Pejman Soroosh, Melissa Swiecki, Deepti Wilkinson
  • Publication number: 20210047435
    Abstract: Disclosed are materials and methods for improved single chain variable fragments.
    Type: Application
    Filed: August 14, 2020
    Publication date: February 18, 2021
    Inventors: Jinquan Luo, Lauren Boucher, Michael Feldkamp, Michael Diem, Anthony A. Armstrong, Alexey Teplyakov, Chichi Huang
  • Publication number: 20210040210
    Abstract: Embodiments of the present invention provide isolated proteins comprising antigen binding domains that bind kallikrein related peptidase 2 (hK2), including monospecific and bispecific antibodies. Additional embodiments of the invention provide polynucleotides encoding the hk2-specific proteins, vectors, host cells, and methods of making and using them.
    Type: Application
    Filed: July 23, 2020
    Publication date: February 11, 2021
    Inventors: Rajkumar Ganesan, John Lee, Jinquan Luo, Theresa McDevitt, Fei Shen, Degang Song, Raymond Brittingham, Sathyadevi Venkataramani, Sanjaya Singh, Yonghong Zhao, Fang Yi, Sherry Lynn La Porte
  • Publication number: 20210002358
    Abstract: Monoclonal anti-tau antibodies and antigen-binding fragments thereof are described. Also described are nucleic acids encoding the antibodies, compositions comprising the antibodies, methods of producing the antibodies and using the antibodies for treating or preventing conditions such as tauopathies. The antibodies of the invention may also be used to quantify tau in biological samples.
    Type: Application
    Filed: March 4, 2019
    Publication date: January 7, 2021
    Inventors: Kristof Van Kolen, Marc Mercken, Linda Barone, Eilyn R. Lacy, Rupesh Nanjunda, John Wheeler, Jinquan Luo, Marianne Borgers