Patents by Inventor Jinque LUO

Jinque LUO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Indolo[2?,3?:3,4]pyrido[2,1-b]quinazoline compound and use thereof
    Patent number: 12590093
    Abstract: The disclosure relates to an indolo[2?,3?:3,4]pyrido[2,1-b]quinazoline compound represented by general formula (I) and use thereof in the manufacture of (1) a medicament for treating a cardiovascular and cerebrovascular disease, (2) a formulation for increasing expression of AMPK, ABCA1 and SR-BI, (3) a formulation for activating nuclear receptors (NRs), and inhibiting activity of NLRP3, IL-1?, NF-?B and MAPKs, (4) a formulation for promoting cellular cholesterol efflux; or (5) a medicament for anti-inflammation.
    Type: Grant
    Filed: September 27, 2020
    Date of Patent: March 31, 2026
    Assignee: INSTITUTE OF MEDICINAL BIOTECHNOLOGY CHINESE ACADEMY OF MEDICAL SCIENCES
    Inventors: Shuyi Si, Yanni Xu, Xiao Wang, Jinque Luo, Yongzhen Li, Chao Liu, Xinhai Jiang, Yining Li, Xiaowan Han, Yan Li, Minghua Chen, Jing Zhang, Xin Zhen
  • GROUP OF TETRAHYDROINDOLOQUINAZOLINE COMPOUNDS AND USE THEREOF
    Publication number: 20220402918
    Abstract: The disclosure relates to an indolo[2?,3?:3,4]pyrido[2,1-b]quinazoline compound represented by general formula (I) and use thereof in the manufacture of (1) a medicament for treating a cardiovascular and cerebrovascular disease, (2) a formulation for increasing expression of AMPK, ABCA1 and SR-BI, (3) a formulation for activating nuclear receptors (NRs), and inhibiting activity of NLRP3, IL-1?, NF-?B and MAPKs, (4) a formulation for promoting cellular cholesterol efflux; or (5) a medicament for anti-inflammation.
    Type: Application
    Filed: September 27, 2020
    Publication date: December 22, 2022
    Inventors: Shuyi SI, Yanni XU, Xiao WANG, Jinque LUO, Yongzhen LI, Chao LIU, Xinhai JIANG, Yining LI, Xiaowan HAN, Yan LI, Minghua CHEN, Jing ZHANG, Xin ZHEN