Abstract: Provided are a method of analyzing biological samples, an analytical chip and an analytical system comprising same, the method comprising the steps of: introducing structures for assisting the formation of bioreactors on a substrate; providing a plurality of bioreactors on the substrate by means of forming the bioreactors, which are holding biological samples, on the peripheral parts of the respective structures so as to come in contact with the structures in at least one region; and checking a change in the biological samples present in the bioreactors.

Abstract: The present invention provides a method for producing a target nucleic acid molecule, including: (a) providing a double-stranded nucleic acid molecule including a target sequence region, a first flanking sequence region linked to the 5? end of the target sequence region and containing one or more deaminated bases, and a second flanking sequence region linked to the 3? end of the target sequence region; and (b) incubating the nucleic acid molecule and an endonuclease specific for the deaminated bases to remove the first flanking sequence region ranging from the deaminated base closest to the 5? end of the target sequence region to the 5? end of the nucleic acid molecule. The present invention also provides a composition for producing a target nucleic acid molecule including the double-stranded nucleic acid molecule and a deaminated base-specific endonuclease.