Abstract: A computer implemented method for merging loops. A number of processor units identifies loops in computer code. The loops are sequences of instructions that are repeated until conditions for the loops are reached. The number of processor units creates a tree comprising nodes that represent the loops and edges that represent relationships between nodes. The number of processor units utilizes the tree to identify a pair of candidate loops from sibling nodes. The number of processor units creates a new loop from the pair of candidate loops with an expanded iteration space based on iteration spaces for the pair of candidate loops in response to the pair of candidate loops being eligible for merging.

Abstract: Disclosed herein are compounds of formula (I), and/or a stereoisomer, a stable isotope, or a pharmaceutically acceptable salt or solvate thereof; and therapeutic uses of these compounds, which are inhibitors of SHP2, potentially useful in the treatment of SHP2-associated diseases, such as SHP2-associated cancers.

Abstract: An ultrasound imaging method, including: using a probe to perform real-time ultrasound imaging on a site to be imaged so as to generate an ultrasound image of the site to be imaged; receiving a location selection on the ultrasound image from an input device; acquiring blood flow information at the selected location on the ultrasound image; and on the basis of the blood flow information at the selected location, in real time, controlling the input device to generate force feedback. Other embodiments of the present application further provide an ultrasound imaging system and a non-transitory computer-readable medium.

Abstract: A method for improving performance of a predefined Deep Neural Network (DNN) convolution processing on a computing device includes inputting parameters, as input data into a processor on a computer that formalizes a design space exploration of a convolution mapping, on a predefined computer architecture that will execute the predefined convolution processing. The parameters are predefined as guided by a specification for the predefined convolution processing to be implemented by the convolution mapping and by a microarchitectural specification for the processor that will execute the predefined convolution processing. The processor calculates performance metrics for executing the predefined convolution processing on the computing device, as functions of the predefined parameters, as proxy estimates of performance of different possible design choices to implement the predefined convolution processing.

Abstract: The present disclosure provides a compound of Formula (I) and/or a stereoisomer, a tautomer, a stable isotope, or a pharmaceutically acceptable salt thereof; and therapeutic uses of these compounds. They are kinase inhibitors potentially useful in the treatment of diseases treatable, such as cancers. Also disclosed herein is a pharmaceutical composition, comprising a compound of Formula (I) and/or a stereoisomer, a tautomer, a stable isotope, or a pharmaceutically acceptable salt thereof; and a pharmaceutically acceptable carrier.

Abstract: A computer implemented method for merging loops. A number of processor units identifies loops in computer code. The loops are sequences of instructions that are repeated until conditions for the loops are reached. The number of processor units creates a tree comprising nodes that represent the loops and edges that represent relationships between nodes. The number of processor units utilizes the tree to identify a pair of candidate loops from sibling nodes. The number of processor units creates a new loop from the pair of candidate loops with an expanded iteration space based on iteration spaces for the pair of candidate loops in response to the pair of candidate loops being eligible for merging.

Abstract: The present disclosure provides a device and methods for determining the original stratum direction of a core. The device includes a confining pressure pump, a resistance meter, and a core holder composed of upper and lower portions. The present disclosure further provides three methods for determining the original stratum direction of the core. The three methods respectively use the device to measure resistance values at different positions of the core, and compare a test result with an imaging result of resistivity imaging logging data to determine the rock direction of the core in a stratum.

Abstract: Among the various aspects of the present disclosure is the provision of compositions and methods of treating or preventing various headache disorders or neuropathic pain by increasing the number of Treg cells in a subject. In particular, low dose IL-2, rapamycin, statin or Treg cell administration are shown to be useful in treating or preventing headache or neuropathic pain.

Abstract: Methods, systems, and circuits for training a neural network include applying noise to a set of training data across wordlines using a respective noise switch on each wordline. A neural network is trained using the noise-applied training data to generate a classifier that is robust against adversarial training.

Abstract: The present disclosure provides a device and methods for determining the original stratum direction of a core. The device includes a confining pressure pump, a resistance meter, and a core holder composed of upper and lower portions. The present disclosure further provides three methods for determining the original stratum direction of the core. The three methods respectively use the device to measure resistance values at different positions of the core, and compare a test result with an imaging result of resistivity imaging logging data to determine the rock direction of the core in a stratum.

Abstract: Disclosed herein are compounds of formula I and/or a stereoisomer, stable isotopologue, and/or pharmaceutically acceptable salts thereof; and therapeutic uses of these compounds, which are inhibitors of tryptophan 2, 3-dioxygenase 2 (TDO2) and/or indoleamine 2, 3-dioxygenase 1 (IDO1), potentially useful in the treatment of diseases treatable, such as cancers.

Abstract: The present disclosure relates to a 2K coating composition comprising a polysiloxane-modified polyurethane and a hardener, wherein the polysiloxane-modified polyurethane obtainable by a method comprising the following steps: a) subjecting a polyol to a reaction with an isocyanate-functional silane coupling agent to obtain a silane-grafted polyol, and b) subjecting the silane-grafted polyol to a condensation reaction with a hydroxyl-functional polysiloxane, to obtain the polysiloxane-modified polyurethane. The polysiloxane-modified polyurethane can be used in a coating composition to form a coating which has smooth feel, stain resistance and easy clean properties, particularly desired in the field of e.g. consumer electronics and automotive industry.

Abstract: A speed reducer, a power system, a straddle-type rail train, and a rail transport system are disclosed. The speed reducer includes: a box body; a speed-reducing mechanism, disposed in the box body; and a support shaft, a first end of the support shaft being supported on the box body, and a second end of the support shaft being connected to a high-speed end of the speed-reducing mechanism. The speed reducer according to the present disclosure achieves a more stable connection between a drive shaft and a speed-reducing mechanism and a more stable power transmission.

Abstract: (I) Disclosed herein are compounds of formula I, and/or a stereoisomer, a stable isotope, or a pharmaceutically acceptable salt or solvate thereof; and therapeutic uses of these compounds, which are inhibitors of rearranged during transfection (RET), potentially useful in the treatment of RET-associated diseases, such as RET-associated cancers.

Abstract: A locking device comprising: first and second flanges; and first and second flange locking structures. The first and second flange locking structures are used for selectively locking the first flange and the second flange. Each flange locking structure comprises: a synchronising ring and a driving assembly. The synchronising ring is able to slide relative to the corresponding flange; and the drive assembly is capable of selectively pushing the synchronising ring to slide along the axial direction of the corresponding flange from an unlocked position to a locked position.

Abstract: (I) Disclosed herein are compounds of formula I, and/or a stereoisomer, a stable isotope, or a pharmaceutically acceptable salt thereof; and therapeutic uses of these compounds, which are kinase inhibitors potentially useful in the treatment of diseases treatable, such as cancers, as well as pharmaceutical compositions, comprising a compound of formula I, and/or a stereoisomer, a stable isotope, or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier.

Abstract: The present disclosure relates to a 2K coating composition comprising a polysiloxane-modified polyurethane and a hardener, wherein the polysiloxane-modified polyurethane obtainable by a method comprising the following steps: a) subjecting a polyol to a reaction with an isocyanate-functional silane coupling agent to obtain a silane-grafted polyol, and b) subjecting the silane-grafted polyol to a condensation reaction with a hydroxyl-functional polysiloxane, to obtain the polysiloxane-modified polyurethane. The polysiloxane-modified polyurethane can be used in a coating composition to form a coating which has smooth feel, stain resistance and easy clean properties, particularly desired in the field of e.g. consumer electronics and automotive industry.

Abstract: A speed reducer, a power system, a straddle-type rail train, and a rail transport system are disclosed. The speed reducer includes: a box body; a speed-reducing mechanism, disposed in the box body; and a support shaft, a first end of the support shaft being supported on the box body, and a second end of the support shaft being connected to a high-speed end of the speed-reducing mechanism. The speed reducer according to the present disclosure achieves a more stable connection between a drive shaft and a speed-reducing mechanism and a more stable power transmission.

Abstract: The present invention discloses a locking device, a power assembly, a power transmission system and a vehicle. The locking device includes: a first flange, the first flange being adapted to be fixed on the first shaft; a second flange, the second flange being adapted to be fixed on the second shaft; a synchronizing ring, the synchronizing ring being normally connected to the first flange to be adapted to rotate synchronously with the first flange, and the synchronizing ring being slidable relative to the first flange; and a driving component, the driving component selectively pushing the synchronizing ring to slide from an unlocked position to a locked position in an axial direction of the first flange. When the synchronizing ring is in the locked position, the synchronizing ring is connected to the second flange be adapted to rotate the second flange synchronously with the first flange. When the synchronizing ring is in the unlocked position, the synchronizing ring is separated from the second flange.

Abstract: The present disclosure provides a compound of Formula (I) and/or a stereoisomer, a tautomer, a stable isotope, or a pharmaceutically acceptable salt thereof; and therapeutic uses of these compounds. They are kinase inhibitors potentially useful in the treatment of diseases treatable, such as cancers. Also disclosed herein is a pharmaceutical composition, comprising a compound of Formula (I) and/or a stereoisomer, a tautomer, a stable isotope, or a pharmaceutically acceptable salt thereof; and a pharmaceutically acceptable carrier.