Abstract: The present disclosure provides a bispecific antibody including a binding domain that binds to CD112R and a binding domain that binds to TIGIT, and the binding domain that binds to CD112R includes: HCDR1, HCDR2 and HCDR3 of the amino acid sequence set forth in SEQ ID NO: 1, and/or LCDR1, LCDR2 and LCDR3 of the amino acid sequence set forth in SEQ ID NO: 2; and the HCDR1, HCDR2, HCDR3, LCDR1, LCDR2 and LCDR3 are defined according to the Kabat, IMGT, Chothia, AbM or Contact numbering system. The present disclosure further provides a polynucleotide encoding the antibody, an expression vector, a host cell and a method for expressing and purifying the antibody, a pharmaceutical composition including the antibody of the present disclosure, and use of the bispecific antibody for treating cancer.

Abstract: A fully-automated terminal crimping device for facilitating cable positioning includes an upper pressing die crimping mechanism, cable positioning mechanisms, an ejection mechanism, a terminal pushing slider mechanism, and a terminal clamping mechanism, where the terminal pushing slider mechanism is arranged directly below the upper pressing die crimping mechanism, a lower pressing die base is arranged on the terminal pushing slider mechanism, the terminal clamping mechanism and the ejection mechanism are arranged at the left and right sides of the lower pressing die base respectively, and the two cable positioning mechanisms are arranged at the front and rear ends of the lower pressing die base respectively.

Abstract: Exemplary methods for quantitative mapping of physical properties, systems and computer-accessible medium can be provided to generate images of tissue magnetic susceptibility, transport parameters and oxygen consumption from magnetic resonance imaging data using the Bayesian inference approach, which minimizes a data fidelity term under a constraint of a structure prior knowledge. The data fidelity term is constructed directly from the magnetic resonance imaging data. The structure prior knowledge can be characterized from known anatomic images using image feature extraction operation or artificial neural network. Thus, according to the exemplary embodiment, system, method and computer-accessible medium can be provided for determining physical properties associated with at least one structure.

Abstract: Exemplary methods for quantitative mapping of physical properties, systems and computer-accessible medium can be provided to generate images of tissue magnetic susceptibility, transport parameters and oxygen consumption from magnetic resonance imaging data using the Bayesian inference approach, which minimizes a data fidelity term under a constraint of a structure prior knowledge. The data fidelity term is constructed directly from the magnetic resonance imaging data. The structure prior knowledge can be characterized from known anatomic images using image feature extraction operation or artificial neural network. Thus, according to the exemplary embodiment, system, method and computer-accessible medium can be provided for determining physical properties associated with at least one structure.

Abstract: The present disclosure relates to a method for generating a quick response QR code and a printing apparatus, a method for generating a quick response (QR) code, comprising obtaining an original image of the QR code, wherein the original image of the QR code is a bitmap image and is a color image or a grayscale image; obtaining information contained in the QR code; and generating a monochrome image of the QR code based on the information.

Abstract: A resource allocation method and apparatus for flight cabin seats. The method includes: acquiring preset startup information and passenger name record PNR information of a target flight; determining a target flight segment according to a preset flight segment priority; comparing sold cabin seat information with saleable cabin seat information of the changed aircraft type, to determine an overflow state of the target flight segment; if the target flight segment is in a state where a flight is not overloaded and a cabin is overloaded, determining overflowed passengers according to a single-cabin overflowed people quantity and a passenger check-in state of an overloaded main cabin; and allocating target cabin seats to the overflowed passengers according to a preset cabin seat mapping rule.

Abstract: The present disclosure is concerned with N-(5-chloro-4-((4-chlorophenyl)(cyano)methyl)-2-methylphenyl)benzamide compounds that are capable of inhibiting SPAK kinase function, methods of treating hypoxic brain injuries due to, for example, ischemic stroke. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Abstract: Exemplary methods for quantitative mapping of physical properties, systems and computer-accessible medium can be provided to generate images of tissue magnetic susceptibility, transport parameters and oxygen consumption from magnetic resonance imaging data using the Bayesian inference approach, which minimizes a data fidelity term under a constraint of a structure prior knowledge. The data fidelity term is constructed directly from the magnetic resonance imaging data. The structure prior knowledge can be characterized from known anatomic images using image feature extraction operation or artificial neural network. Thus, according to the exemplary embodiment, system, method and computer-accessible medium can be provided for determining physical properties associated with at least one structure.

Abstract: A sprinkler includes a sprinkler head and a handle, the sprinkler head is connected with the handle and is arranged to penetrate through the inside of the handle, a water inlet connected with an external water pipe is formed on a tail portion of the handle, a sprinkling surface is disposed on a front end surface of the sprinkler head, a plurality of water outlets are formed on the sprinkling surface, a first filter screen and a second filter screen are further disposed in the sprinkler head, the first filter screen is close to the water outlets, and a filter material or filter cotton for filtering is disposed between the first filter screen and the second filter screen.

Abstract: The present disclosure is concerned with N-(5-chloro-4-((4-chlorophenyl)(cyano)methyl)-2-methylphenyl)benzamide compounds that are capable of inhibiting SPAK kinase function, methods of treating hypoxic brain injuries due to, for example, ischemic stroke. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Abstract: The present disclosure is concerned with N-(5-chloro-4-((4-chlorophenyl)(cyano)methyl)-2-methylphenyl)benzamide compounds that are capable of inhibiting SPAK kinase function, methods of treating hypoxic brain injuries due to, for example, ischemic stroke. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Abstract: A sprinkler includes a sprinkler head and a handle, the sprinkler head is connected with the handle and is arranged to penetrate through the inside of the handle, a water inlet connected with an external water pipe is formed on a tail portion of the handle, a sprinkling surface is disposed on a front end surface of the sprinkler head, a plurality of water outlets are formed on the sprinkling surface, a first filter screen and a second filter screen are further disposed in the sprinkler head, the first filter screen is close to the water outlets, and a filter material or filter cotton for filtering is disposed between the first filter screen and the second filter screen.

Abstract: Disclosed is a sprinkler convenient to stop water. The sprinkler convenient to stop the water includes a housing and a water stop switch, the water stop switch includes a through hole arranged on the housing in a penetration manner and a water stop rod slidably disposed in the through hole, a water inlet communicating with a water inlet channel and a water outlet communicating with a water outlet channel are respectively formed at two sides of the through hole, a water passing hole is formed on a middle portion of the water stop rod in a penetration manner, and a water stop sealing cap matched with the water outlet is further disposed on the water stop rod and is located at one side, close to the water outlet, of the water stop rod.