Patents by Inventor Jinxia Deng

Jinxia Deng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted pyrimidyl guanidine derivatives having anticancer activity
    Patent number: 8445677
    Abstract: Disclosed are pyrimidyl guanidine derivatives having anticancer activity. The pyimidyl guanidine derivatives have the structure: R1 is a cyclic (1-7 member) or acyclic (1-7 member) aliphatic, aromatic, heterocyclic groups optionally substituted, R2 is a cyclic (3-7 member) aliphatic, aromatic, heterocyclic groups optionally substituted by functional groups and R3 is a cyclic (3-7 member) aliphatic, aromatic, heterocyclic groups.
    Type: Grant
    Filed: October 22, 2009
    Date of Patent: May 21, 2013
    Assignee: University of Southern California
    Inventors: Nouri Neamati, Jinxia Deng
  • DISCOVERY OF NOVEL ANTICANCER COMPOUNDS BASED ON CONFORMATIONAL SAMPLING OF QUINOXALINHYDRAZIDE PHARMACOPHORE
    Publication number: 20100160313
    Abstract: The present invention relates in general to anti-cancer drug design. More specifically, the invention provides methods of mapping and screening for anti-cancer agents using pharmacophore models. The invention demonstrates that, conformational sampling of a small lead molecule, followed by representative pharmacophore model development, is an efficient approach for rational design of novel anticancer agents with similar or better potency than the original lead but with different physicochemical properties.
    Type: Application
    Filed: October 22, 2009
    Publication date: June 24, 2010
    Applicant: University of Southern California
    Inventors: Nouri NEAMATI, Jinxia Deng