Patents by Inventor Jinxiang Zeng

Jinxiang Zeng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PREPARATION METHOD FOR AND CRYSTAL FORM OF 3-ARYLOXY-3-FIVE-MEMBERED HETEROARYLPROPYLAMINE COMPOUND
    Publication number: 20230339920
    Abstract: Provided are a compound as represented by formula I, a preparation method therefor, and a hydrochloride crystal form A thereof. The compound as represented by formula I and the hydrochloride crystal form A thereof have excellent inhibitory effects on transient receptor potential (TRP) channels, and have good therapeutic effects on TRP channel-associated diseases.
    Type: Application
    Filed: February 9, 2021
    Publication date: October 26, 2023
    Inventors: Juan YU, Youxin WANG, Tingting YIN, Jinxiang ZENG, Lingling ZHANG, Qiang DING
  • Method for preparing pyrrolidinyl urea derivative
    Patent number: 11691965
    Abstract: Disclosed is a method for preparing a pyrrolidinyl urea derivative, which acts as a TrkA inhibitor, and further disclosed are an intermediate compound of a compound of formula (I) and a preparation method therefor.
    Type: Grant
    Filed: January 8, 2021
    Date of Patent: July 4, 2023
    Assignee: ZHANGZHOU PIEN TZE HUANG PHARMACEUTICAL CO., LTD.
    Inventors: Jinming Huang, Juan Yu, Jinxiang Zeng, Limei Yang, Tingting Yin, Yang Zhang, Wentao Wu, Zhixiang Li, Jian Qin
  • METHOD FOR PREPARING PYRROLIDINYL UREA DERIVATIVE
    Publication number: 20230065496
    Abstract: Disclosed is a method for preparing a pyrrolidinyl urea derivative, which acts as a TrkA inhibitor, and further disclosed are an intermediate compound of a compound of formula (I) and a preparation method therefor.
    Type: Application
    Filed: January 8, 2021
    Publication date: March 2, 2023
    Inventors: Jinming HUANG, Juan YU, Jinxiang ZENG, Limei YANG, Tingting YIN, Yang ZHANG, Wentao WU, Zhixiang LI, Jian QIN
  • Pyrazine-2(1H)-ketone compound preparation method
    Patent number: 11535609
    Abstract: Provided are preparation methods for the chemical compound represented by formula (I) and an intermediate thereof.
    Type: Grant
    Filed: August 4, 2020
    Date of Patent: December 27, 2022
    Assignee: ZHANGZHOU PIEN TZE HUANG PHARMACEUTICAL CO., LTD.
    Inventors: Jinming Huang, Juan Yu, Jinxia Lin, Limei Yang, Jinxiang Zeng, Zhifei Fu, Miaorong Luo, Yang Zhang, Jian Li, Shuhui Chen
  • PYRAZINE-2(1H)-KETONE COMPOUND PREPARATION METHOD
    Publication number: 20220380350
    Abstract: Provided are preparation methods for the chemical compound represented by formula (I) and an intermediate thereof.
    Type: Application
    Filed: August 4, 2020
    Publication date: December 1, 2022
    Inventors: Jinming HUANG, Juan YU, Jinxia LIN, Limei YANG, Jinxiang ZENG, Zhifei FU, Miaorong LUO, Yang ZHANG, Jian LI, Shuhui CHEN
  • Total flavonoids extract of Kitam., preparation method therefor and use thereof for treating hyperuricemia
    Patent number: 11298390
    Abstract: Disclosed is a total flavonoids extract of Gynura formosana Kitam., containing 80%-85% of rutin by weight percent content. The results of pharmacological experiments show that the extract can lower the activity of xanthine oxidase in the liver of a hyperuricemia model mouse and reduce the synthesis of uric acid to a certain degree and has a certain uric acid-lowering effect, and can be used as a potential drug for treating hyperuricemia or gout. The method for preparing the total flavonoids extract of Gynura formosana Kitam. comprises: after an extraction step, selecting a complex enzyme composed of enzymes with a specific composition and a specific ratio for enzymolosis, and further carrying out the step of extracting and concentrating with macroporous resin and isolating and purifying with macroporous resin, so that the HPLC purity of rutin in the resulting total flavonoids extract of Gynura formosana Kitam. reaches 80%-85%.
    Type: Grant
    Filed: March 17, 2020
    Date of Patent: April 12, 2022
    Assignee: Zhangzhou Pien Tze Huang Pharmaceutical Co., Ltd.
    Inventors: Huijun Yuan, Tingting Yin, Fei Hong, Juan Yu, Jinxiang Zeng, Shicong Wang
  • Total Flavonoids Extract of Gynura Formosana Kitam., Preparation Method Therefor and Use Thereof for Treating Hyperuricemia
    Publication number: 20200222484
    Abstract: Disclosed is a total flavonoids extract of Gynura formosana Kitam., containing 80%-85% of rutin by weight percent content. The results of pharmacological experiments show that the extract can lower the activity of xanthine oxidase in the liver of a hyperuricemia model mouse and reduce the synthesis of uric acid to a certain degree and has a certain uric acid-lowering effect, and can be used as a potential drug for treating hyperuricemia or gout. The method for preparing the total flavonoids extract of Gynura formosana Kitam. comprises: after an extraction step, selecting a complex enzyme composed of enzymes with a specific composition and a specific ratio for enzymolosis, and further carrying out the step of extracting and concentrating with macroporous resin and isolating and purifying with macroporous resin, so that the HPLC purity of rutin in the resulting total flavonoids extract of Gynura formosana Kitam. reaches 80%-85%.
    Type: Application
    Filed: March 17, 2020
    Publication date: July 16, 2020
    Inventors: Huijun Yuan, Tingting Yin, Fei Hong, Juan Yu, Jinxiang Zeng, Shicong Wang