Patents by Inventor Jinxiu Zhang

Jinxiu Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9677133
    Abstract: A hybridization system is provided, which comprises a biological chip having a substrate (1) with a probe dot matrix (3) and a cover plate (2) with at least two through-holes (4), where a hybrid chamber (5) is formed between the substrate (1) and the cover plate (2), at least two fluid channels (6) are interconnected respectively with the hybrid chamber (5) by the two through-holes (4), and a fluid control device is interconnected with the fluid channels (6). The biological chip hybridization system integrates hybridizing, cleaning and drying functions, uses power provided by the fluid control device as the drive force for promoting the liquid flow for automatically reciprocation flow in the fluid channels (6) and the chamber (5) to achieve a dynamic hybridization, thus improving the hybrid efficiency and uniformity, and achieving automatic control.
    Type: Grant
    Filed: February 10, 2012
    Date of Patent: June 13, 2017
    Assignees: CAPITALBIO CORPORATION, TSINGHUA UNIVERSITY
    Inventors: Jiaming Ye, Pinhong Wang, Guoqing Wang, Liqing Duan, Kaijun Zhao, Jinxiu Zhang, Xiumei Song, Dong Wang, Huafang Gao, Wanli Xing
  • Publication number: 20140011707
    Abstract: A hybridization system is provided, which comprises a biological chip having a substrate (1) with a probe dot matrix (3) and a cover plate (2) with at least two through-holes (4), where a hybrid chamber (5) is formed between the substrate (1) and the cover plate (2), at least two fluid channels (6) are interconnected respectively with the hybrid chamber (5) by the two through-holes (4), and a fluid control device is interconnected with the fluid channels (6). The biological chip hybridization system integrates hybridizing, cleaning and drying functions, uses power provided by the fluid control device as the drive force for promoting the liquid flow for automatically reciprocation flow in the fluid channels (6) and the chamber (5) to achieve a dynamic hybridization, thus improving the hybrid efficiency and uniformity, and achieving automatic control.
    Type: Application
    Filed: February 10, 2012
    Publication date: January 9, 2014
    Applicants: TSINGHUA UNIVERSITY, CAPITALBIO CORPORATION
    Inventors: Jiaming Ye, Pinhong Wang, Guoqing Wang, Liqing Duan, Kaijun Zhao, Jinxiu Zhang, Xiumei Song, Dong Wang, Huafang Gao, Wanli Xing
  • Publication number: 20130206250
    Abstract: Provided are a bubble-based microvalve and a microfluidic chip using the microvalve. Also provided are methods of using the microvalve for manipulating fluid in a microfluidic channel by changing the volume and/or location of the gas in the microvalve.
    Type: Application
    Filed: July 1, 2011
    Publication date: August 15, 2013
    Applicant: Tsinghua University
    Inventors: Guohao Zhang, Su Guo, Can Wang, Guoqing Wang, Miao Liu, Jinxiu Zhang, Bei Han, Tao Deng, Wanli Xing, Jing Cheng
  • Publication number: 20130210675
    Abstract: Provided are compositions for controlled release of biomolecules, which comprise conjugates of polymers and biomolecules conjugated through non-covalent interactions. Also provided are methods for controlled release of biomolecules and their use in biochips.
    Type: Application
    Filed: July 13, 2011
    Publication date: August 15, 2013
    Applicant: CapitalBio Corporation
    Inventors: Su Guo, Guoqing Wang, Guohao Zhang, Can Wang, Bei Han, Miao Liu, Jinxiu Zhang, Tao Deng, Wanli Xing, Jing Cheng