Patents by Inventor Jinyong Wang

Jinyong Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250129333
    Abstract: Provided are a RIC cell, and a preparation method therefor and application thereof. The present invention particularly relates to the lineage-specific differentiation of a pluripotent or multipotent stem cell, specifically to a RIC cell differentiated from a stem cell, and a preparation method therefor and application thereof.
    Type: Application
    Filed: July 11, 2022
    Publication date: April 24, 2025
    Applicants: INSTITUTE OF ZOOLOGY, CHINESE ACADEMY OF SCIENCES, BEIJING INSTITUTE FOR STEM CELL AND REGENERATIVE MEDICINE
    Inventors: Jinyong Wang, Dehao HUANG, Jianhuan LI, Fangxiao HU, Tongjie WANG, Chengxiang XIA, Baoyang HU, Jie HAO, Lei WANG, Liu WANG
  • Publication number: 20240269181
    Abstract: A method for regenerating a humoral immunity system. A pluripotent stem cell is used for expressing a RUNX1 gene, a HOXA9 gene and an LHX2 gene to efficiently obtain B cell seeds after in vitro induction differentiation, and after transplantation, a complete humoral immune system can be reconstructed in an animal in which the humoral immune system is missing. According to the method, an antigen-specific antibody immune response can be realized, a specific high-affinity antibody can be generated against an antigen, and immunological memory can be produced. Meanwhile, the reconstructed immune system is safe, and carries no risk of tumorigenicity.
    Type: Application
    Filed: April 8, 2022
    Publication date: August 15, 2024
    Inventors: Jinyong WANG, Qi ZHANG, Bingyan WU, Fangxiao HU, Qitong WENG, Huan PENG, Yao WANG, Lijuan LIU, Xiaofei LIU, Chengxiang XIA, Yang GENG, Hongling WU
  • Publication number: 20230405521
    Abstract: Staged absorption ammonia-based decarbonization using an absorption circulating liquid containing ammonium salts to remove carbon dioxide in a gas, and control ammonia escape while realizing efficient decarbonization through staged solution composition control and reaction condition control. Staged solution composition control may include concentration gradient control of ammonium carbonate, ammonium bicarbonate, ammonium carbamate, ammonia, or combinations thereof, which may be characterized by the molar ratio of total ammonia to total CO2. Reaction condition control may include temperature control, pH control, and pressure control. The flue gas may enter the decarbonization tower, and through staged absorption, establishment of concentration, temperature, and multi-point addition of ammonia, decarbonization efficiency may be improved, decarbonization operating costs may be saved, and ammonia escape may be controlled.
    Type: Application
    Filed: May 12, 2023
    Publication date: December 21, 2023
    Inventors: Jun Zhang, Lifang Qi, Jinyong Wang, Jing Luo
  • Publication number: 20230405519
    Abstract: Apparatus and methods for controlling ammonia escape in an ammonia-based decarbonization system, wherein ammonia may be used as the desulfurization and decarbonization agent, the gas may first enter the desulfurization device for desulfurization to produce ammonium sulfate fertilizer, and the desulfurized gas may enter the decarbonization device to remove carbon dioxide in the gas, and may produce ammonium bicarbonate fertilizer. The decarbonized gas may include free ammonia, and the free ammonia in the gas may be absorbed with the acidic ammonium sulfate solution and acidic water washing liquid of ammonia-based desulfurization.
    Type: Application
    Filed: May 12, 2023
    Publication date: December 21, 2023
    Inventors: Jing Luo, Jun Zhang, Lifang Qi, Jinyong Wang
  • Publication number: 20230373800
    Abstract: Device and methods for producing ammonium bicarbonate in an ammonia-based decarbonization system are provided. The device may include a cooling function zone, an ammonium bicarbonate generation zone, a carbon dioxide absorption zone and an ammonia removal function zone. The cooling function zone may remove heat from the decarbonization system. The ammonium bicarbonate generation zone may generate ammonium bicarbonate. The carbon dioxide absorption zone, which may use multi-stage absorption, may absorb carbon dioxide in process gas. The ammonia removal function zone may remove ammonia in decarbonized process gas. Absorbent ammonia for carbon dioxide removal may be mainly fed to the absorption zone. As a result of the zone control of ammonium bicarbonate generation, CO2 absorption and ammonia removal, the efficiency of decarbonization and absorption may be improved, and ammonia escape may be reduced. Meanwhile, carbon dioxide in flue gas can be used for producing ammonium bicarbonate as a nitrogen fertilizer.
    Type: Application
    Filed: May 15, 2023
    Publication date: November 23, 2023
    Inventors: Jun Zhang, Jinyong Wang, Lifang Qi, Jing Luo
  • Publication number: 20230373801
    Abstract: Multi-stage ammonia-based decarbonization, characterized in that ammonia is used as an absorbent to absorb CO2 in a process gas in an absorber, and the absorber may include four or more stages of absorption, where a first-stage absorption, a second-stage absorption, a third-stage absorption, a fourth-stage absorption, and higher-stage absorptions may be sequentially arranged along the flow direction of the process gas; and the temperature of the process gas in the second and third-stage absorptions may be controlled not to be lower than the temperature of the process gas in the first-stage absorption, and the temperature of the process gas in the fourth and any higher-stage absorptions may be controlled to be lower than the temperature of the process gas in the first-stage absorption.
    Type: Application
    Filed: May 16, 2023
    Publication date: November 23, 2023
    Inventors: Jun Zhang, Lifang Qi, Jinyong Wang, Jing Luo
  • Publication number: 20230364553
    Abstract: Ammonia-based decarbonization cooling apparatus and a method therefor. The cooling apparatus may include: a first-stage cooling function zone which may use a first circulating liquid to cool a process gas to a temperature of Tgas 1, a second-stage cooling function zone which may use a second circulating liquid to cool the process gas to a temperature of Tgas 2, and a third-stage cooling function zone which may use a third circulating liquid to cool the process gas to a temperature of Tgas 3, wherein Tgas 3<Tgas 2<Tgas 1<Tgas 0, and Tgas 0 is an initial temperature of the process gas when entering the first-stage cooling function zone; a first cold source for cooling the first circulating liquid, a second cold source for cooling the second circulating liquid, and a third cold source for cooling the third circulating liquid, wherein the three cold sources may be different.
    Type: Application
    Filed: May 9, 2023
    Publication date: November 16, 2023
    Inventors: Jing Luo, Jun Zhang, Jinyong Wang, Lifang Qi
  • Publication number: 20230366629
    Abstract: Waste heat recovery in an ammonia-based desulfurization and decarbonization system. The heat in the decarbonization system may be removed by using the heat of the process gas before desulfurization. The process gas before desulfurization may heat an intermediate medium through a gas heat exchanger. The intermediate medium may drive a refrigerator for refrigeration. A refrigerant may obtain the cooling capacity and may then cool the decarbonized process gas through a liquid-liquid heat exchanger.
    Type: Application
    Filed: May 9, 2023
    Publication date: November 16, 2023
    Inventors: Jing Luo, Jinyong Wang, Jun Zhang, Lifang Qi
  • Patent number: 11299709
    Abstract: The present invention provides a pluripotent stem cell comprising a co-expression vector in which Runx1 and Hoxa9 are of in tandem, and a T cell differentiated therefrom and application thereof. In the present invention, Pluripotent stem cells inducibly co-expressing exogenous Runx1 and Hoxa9 are successfully established by introducing an exogenous vector co-expressing Runx1 and Hoxa9 into pluripotent stem cells. The pluripotent stem cells are directionally differentiated into T-lineage progenitor cells and will be developed into T cells. The pluripotent stem cell-derived T cells obtained by the method of the present invention are not only functionally normal but also have no tumorigenic risk.
    Type: Grant
    Filed: January 11, 2018
    Date of Patent: April 12, 2022
    Assignee: GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH CHINESE ACADEMY OF SCIENCES
    Inventors: Jinyong Wang, Rongqun Guo, Mengyun Zhang, Lijuan Liu, Xiaofei Liu, Cui Lv, Juan Du
  • Patent number: 11224838
    Abstract: Controlling aerosol production during absorption in ammonia-based desulfurization. The absorption reaction temperature, the oxygen content and water content of the process gas may be controlled, and an absorption circulating liquid containing ammonium sulfite may be used for removing sulfur dioxide in flue gas, so as to control aerosol production during absorption in the ammonia-based desulfurization.
    Type: Grant
    Filed: July 22, 2020
    Date of Patent: January 18, 2022
    Assignee: Jiangnan Environmental Protection Group Inc.
    Inventors: Jing Luo, Yongying Luo, Jinyong Wang
  • Publication number: 20210238548
    Abstract: The present invention provides a pluripotent stem cell comprising a co-expression vector in which Runx1 and Hoxa9 are of in tandem, and a T cell differentiated therefrom and application thereof. In the present invention, Pluripotent stem cells inducibly co-expressing exogenous Runx1 and Hoxa9 are successfully established by introducing an exogenous vector co-expressing Runx1 and Hoxa9 into pluripotent stem cells. The pluripotent stem cells are directionally differentiated into T-lineage progenitor cells and will be developed into T cells. The pluripotent stem cell-derived T cells obtained by the method of the present invention are not only functionally normal but also have no tumorigenic risk.
    Type: Application
    Filed: January 11, 2018
    Publication date: August 5, 2021
    Inventors: Jinyong WANG, Rongqun GUO, Mengyun ZHANG, Lijuan LIU, Xiaofei LIU, Cui LV, Juan DU
  • Publication number: 20210197117
    Abstract: Controlling aerosol production during absorption in ammonia-based desulfurization.
    Type: Application
    Filed: July 22, 2020
    Publication date: July 1, 2021
    Inventors: Jing Luo, Yongying Luo, Jinyong Wang
  • Publication number: 20200208107
    Abstract: The present invention provides a pluripotent stein cell comprising a co-expression vector in which Runx1 and Hoxa9 are of in tandem, and a T cell differentiated therefrom and application thereof. In the present invention, Pluripotent stein cells inducibly co-expressing exogenous Runx1 and Hoxa9 are successfully established by introducing an exogenous vector co-expressing Runx1 and Hoxa9 into pluripotent stein cells. The pluripotent stein cells are directionally differentiated into T-lineage progenitor cells and will be developed into T cells. The pluripotent stein cell-derived T cells obtained by the method of the present invention are not only functionally normal but also have no tumorigenic risk.
    Type: Application
    Filed: January 11, 2018
    Publication date: July 2, 2020
    Inventors: Jinyong WANG, Rongqun GUO, Mengyun ZHANG, Lijuan LIU, Xiaofei LIU, Cui LV, Juan DU
  • Patent number: 10589212
    Abstract: Ammonia-adding apparatus and methods for ammonia-based desulfurization use multi-stage control, calculate a theoretical amount of ammonia based on gas amounts provided by an inlet continuous emission monitoring system (CEMS) and an outlet CEMS of the ammonia-based desulfurization device or associated gas amounts, a SO2 concentration provided by the inlet CEMS, and a predetermined SO2 concentration of the outlet CEMS. The apparatus and methods calculate a corrected theoretical amount of ammonia using half of the ratio of the actual amount of added ammonia to the actual amount of removed sulfur dioxide as a correction coefficient for the theoretical amount of ammonia; add an ammonia absorbent equivalent to the corrected theoretical amount of ammonia to the ammonia-based desulfurization device through an ammonia metering means and an ammonia control valve, and automatically control the actual ammonia flow rate based on the actual SO2 concentration and a change trend provided by the outlet CEMS.
    Type: Grant
    Filed: April 8, 2019
    Date of Patent: March 17, 2020
    Assignee: Jiangnan Environmental Protection Group Inc.
    Inventors: Jing Luo, Jinyong Wang, Jun Zhang
  • Patent number: 10583386
    Abstract: Ammonia-adding apparatus and methods for ammonia-based desulfurization use multi-stage control, calculate a theoretical amount of ammonia based on gas amounts provided by an inlet continuous emission monitoring system (CEMS) and an outlet CEMS of the ammonia-based desulfurization device or associated gas amounts, a SO2 concentration provided by the inlet CEMS, and a predetermined SO2 concentration of the outlet CEMS. The apparatus and methods calculate a corrected theoretical amount of ammonia using half of the ratio of the actual amount of added ammonia to the actual amount of removed sulfur dioxide as a correction coefficient for the theoretical amount of ammonia; add an ammonia absorbent equivalent to the corrected theoretical amount of ammonia to the ammonia-based desulfurization device through an ammonia metering means and an ammonia control valve, and automatically control the actual ammonia flow rate based on the actual SO2 concentration and a change trend provided by the outlet CEMS.
    Type: Grant
    Filed: October 12, 2018
    Date of Patent: March 10, 2020
    Assignee: Jiangnan Environmental Protection Group Inc.
    Inventors: Jing Luo, Jinyong Wang, Jun Zhang
  • Patent number: 10543451
    Abstract: Ammonia-adding apparatus and methods for ammonia-based desulfurization use multi-stage control, calculate a theoretical amount of ammonia based on gas amounts provided by an inlet continuous emission monitoring system (CEMS) and an outlet CEMS of the ammonia-based desulfurization device or associated gas amounts, a SO2 concentration provided by the inlet CEMS, and a predetermined SO2 concentration of the outlet CEMS. The apparatus and methods calculate a corrected theoretical amount of ammonia using half of the ratio of the actual amount of added ammonia to the actual amount of removed sulfur dioxide as a correction coefficient for the theoretical amount of ammonia; add an ammonia absorbent equivalent to the corrected theoretical amount of ammonia to the ammonia-based desulfurization device through an ammonia metering means and an ammonia control valve, and automatically control the actual ammonia flow rate based on the actual SO2 concentration and a change trend provided by the outlet CEMS.
    Type: Grant
    Filed: October 12, 2018
    Date of Patent: January 28, 2020
    Assignee: Jiangnan Environmental Protection Group Inc.
    Inventors: Jing Luo, Jinyong Wang, Jun Zhang
  • Patent number: 10537845
    Abstract: Ammonia-adding apparatus and methods for ammonia-based desulfurization use multi-stage control, calculate a theoretical amount of ammonia based on gas amounts provided by an inlet continuous emission monitoring system (CEMS) and an outlet CEMS of the ammonia-based desulfurization device or associated gas amounts, a SO2 concentration provided by the inlet CEMS, and a predetermined SO2 concentration of the outlet CEMS. The apparatus and methods calculate a corrected theoretical amount of ammonia using half of the ratio of the actual amount of added ammonia to the actual amount of removed sulfur dioxide as a correction coefficient for the theoretical amount of ammonia; add an ammonia absorbent equivalent to the corrected theoretical amount of ammonia to the ammonia-based desulfurization device through an ammonia metering means and an ammonia control valve, and automatically control the actual ammonia flow rate based on the actual SO2 concentration and a change trend provided by the outlet CEMS.
    Type: Grant
    Filed: April 8, 2019
    Date of Patent: January 21, 2020
    Assignee: Jiangnan Environmental Protection Group Inc.
    Inventors: Jing Luo, Jinyong Wang, Jun Zhang
  • Patent number: 10508287
    Abstract: The present invention relates to a method for inducing the transdifferentiation of B lymphoid cells into T lymphoid cells using transcription factor Hoxb5, and related products and applications thereof. The method of the present invention specifically comprises: introducing Hoxb5, a nucleic acid molecule encoding Hoxb5 or a construct comprising the nucleic acid molecule into the B lymphoid cells to obtain the B lymphoid cells with overexpressed Hoxb5; then implanting the obtained B lymphoid cells into the body of a subject to obtain regenerated T cell progenitor cells by way of transdifferentiation, and then the T cell progenitor cells differentiate into mature T cells with functions. The regenerated T cells obtained using the method of the present invention are not only functionally normal, but also show no risk of tumorigenesis or extremely low risk of tumorigenesis.
    Type: Grant
    Filed: December 28, 2016
    Date of Patent: December 17, 2019
    Assignee: Guangzhou Institutes of Biomedicine and Health Chinese Academy of Sciences
    Inventors: Jinyong Wang, Dan Yang, Yong Dong, Fangxiao Hu, Qianhao Zhao, Mengyun Zhang, Cui Lv, Ying Wang
  • Patent number: 10493106
    Abstract: The present invention discloses a method for remolding bone marrow microenvironment in a subject having an impaired bone marrow microenvironment, which comprises implanting a composition comprising isolated mesenchymal stromal cells (MSCs) into the bone marrow cavity of the subject. The method of the present invention successfully remolds the bone marrow microenvironment, recovers the normal hematopoiesis of bone marrow, inhibits/delays the pathological process of leukemia and significantly prolongs the survival period. In addition, the method according to the present invention can be used for the treatment of hematologic tumors such as leukemia and aplastic anemia (AA), which is safe and effective but has no side effects.
    Type: Grant
    Filed: January 12, 2018
    Date of Patent: December 3, 2019
    Assignee: GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH, CHINESE ACADEMY OF SCIENCES
    Inventors: Jinyong Wang, Chengxiang Xia, Yong Dong, Tongjie Wang, Xiaofei Liu, Juan Du, Yang Geng, Lijuan Liu, Hongling Wu
  • Patent number: 10449488
    Abstract: Apparatus and methods for controlling aerosol production during absorption in ammonia desulfurization, by removing sulfur dioxide in flue gas with an absorption circulation liquid containing ammonium sulfite, so as to control the aerosol production during absorption in ammonia desulfurization. Efficient desulfurization and dust removal may be achieved by staged solution composition control and reaction condition control. At the same time ammonia escape and aerosol production during absorption may be controlled. The flue gas may be subjected to preliminary temperature lowering and purification, and may be allowed to contact with an absorption circulation liquid and a fine particle washing circulation liquid sequentially. Levels of solution compositions and reaction temperatures may be controlled.
    Type: Grant
    Filed: March 29, 2019
    Date of Patent: October 22, 2019
    Assignee: Jiangnan Environmental Protection Group Inc.
    Inventors: Jing Luo, Lifang Qi, Jinyong Wang