Abstract: The present application relates to compositions for preventing or treating infections. In some embodiments, the present application provides chimeric proteins comprising a target-binding moiety comprising an extracellular binding domain (EBD) of an angiotensin-converting enzyme 2 (ACE2) protein or a fragment thereof that specifically binds to an S protein, and a positively charged mucoadhesive peptide fragment. Compositions comprising the chimeric proteins described herein are useful for preventing or treating a viral infection in an individual, such as a coronavirus infection.

Abstract: The present application provides chimeric proteins comprising an antibody moiety that specifically binds to a component of an influenza virus or a variant thereof, and a positively charged mucoadhesive peptide fragment. Compositions comprising the chimeric proteins described herein are useful for preventing or treating an infection caused by an influenza virus or a variant thereof in an individual.

Abstract: A method for scheduling and displaying three-dimensional annotations is provided, relating to the field of realistic three-dimensional visualization technology. The present disclosure covers data services, data scheduling schemes, data storage schemes, annotation avoidance schemes, and annotation efficient display schemes. Users can use this disclosure to schedule and display massive three-dimensional annotations in WebGL at high frame rates while consuming extremely low performance. It solves the problem of text inversion and non-hierarchical zooming of three-dimensional maps in traditional annotation and slicing services which can cause text to appear larger or smaller, breaking through the technical bottleneck that traditional annotation and slicing services that cannot be superposition displayed on 3D models.

Abstract: A method for scheduling and displaying three-dimensional annotations is provided, relating to the field of realistic three-dimensional visualization technology. The present disclosure covers data services, data scheduling schemes, data storage schemes, annotation avoidance schemes, and annotation efficient display schemes. Users can use this disclosure to schedule and display massive three-dimensional annotations in WebGL at high frame rates while consuming extremely low performance. It solves the problem of text inversion and non-hierarchical zooming of three-dimensional maps in traditional annotation and slicing services which can cause text to appear larger or smaller, breaking through the technical bottleneck that traditional annotation and slicing services that cannot be superposition displayed on 3D models.

Abstract: The present invention relates to a method and an apparatus for failure recovery in a network system, wherein a linked list is created, where each network node knows the network address of its neighbor node in at least one direction, wherein each network node sends a beacon to its neighbor node and has its neighbor node acknowledge receipt of the beacon, and wherein a network node checks with a switch device the port status of a port to which a neighbor node that has failed is connected in order to identify a replacement node.

Abstract: The present disclosure relates to methods of treating heat shock factor 1 (HSF1)-related diseases such as cancer autoimmune and viral diseases, using a therapeutically effective amount of a RNAi agent to HSF.

Abstract: The present disclosure relates to methods of treating heat stock factor 1 (HSF1)-related diseases such as cancer, autoimmune and viral diseases, using a therapeutically effective amount of a RNAi agent to HSF.

Abstract: The present invention relates to a method and an apparatus for failure recovery in a network system, wherein a linked list is created, where each network node knows the network address of its neighbor node in at least one direction, wherein each network node sends a beacon to its neighbor node and has its neighbor node acknowledge receipt of the beacon, and wherein a network node checks with a switch device the port status of a port to which a neighbor node that has failed is connected in order to identify a replacement node.

Abstract: The present disclosure relates to methods of treating heat stock factor 1 (HSF1)-related diseases such as cancer, autoimmune and viral diseases, using a therapeutically effective amount of a RNAi agent to HSF.

Abstract: The invention is directed, in part, to selective cancer treatment regimes based on assaying for the presence or absence of a mutation in a nucleic acid that encodes MLL1 or for the presence of reduced levels of MLL1.

Abstract: The present disclosure relates to methods of treating heat shock factor 1 (HSF1)-related diseases such as cancer, autoimmune and viral diseases, using a therapeutically effective amount of a RNAi agent to HSF.

Abstract: The present disclosure relates to methods of treating heat shock factor 1 (HSF1)-related diseases such as cancer and viral diseases, using a therapeutically effective amount of a RNAi agent to HSF.