Patents by Inventor Jinyun YUAN

Jinyun YUAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200209226
    Abstract: A labeled complex, the preparation method thereof, a kit, containing the same, the application of the kit and a detection system comprising the kit are provided. The labeled complex comprises: an antigen; a marker protein coupled with the antigen to form a labeled-complex intermediate; and a signal generation substance coupled with the labeled-complex intermediate to form the labeled complex.
    Type: Application
    Filed: January 20, 2017
    Publication date: July 2, 2020
    Inventors: Wei RAO, Zhonggang FANG, Jinyun YUAN, Yanmei WANG, Tinghua LI, Xiaoli WANG
  • Patent number: 10472400
    Abstract: A cardiac troponin I ultra-sensitive detection reagent kit, a preparation method, and a detection method. The reagent kit comprises at least one first anti-cardiac troponin I antibody marked with a trace marker and at least one second anti-cardiac troponin I antibody coated on magnetic microspheres, the first anti-cardiac troponin I antibody and cardiac troponin I binding site being different from the second anti-cardiac troponin I antibody and cardiac troponin I binding site. The reagent kit may further comprise a diluent capable of significantly reducing non-specific binding in a detection process, so as to further increase the detection accuracy and sensitivity. The method using the reagent kit to detect cardiac troponin I sensitively and accurately detects the amount of cardiac troponin I in a sample, and provides more timely and reliable information for the early diagnosis and treatment of AMI.
    Type: Grant
    Filed: February 10, 2015
    Date of Patent: November 12, 2019
    Assignee: SHENZHEN NEW INDUSTRIES BIOMEDICAL ENGINEERING CO., LTD
    Inventors: Wei Rao, Jinyun Yuan, Qin Li, Sheng Wang, Hong Xu, Wu Li, Tinghua Li, Jinqiu Fu
  • Patent number: 10451624
    Abstract: A reagent kit used for detecting lipoprotein-associated phospholipase A2, and a preparation method for the reagent kit. The reagent kit comprises one or a plurality of first anti-lipoprotein-associated phospholipase A2 antibodies used for binding lipoprotein-associated phospholipase A2 to be measured, and one or a plurality of second anti-lipoprotein-associated phospholipase A2 antibodies marked with a trace marker and binding with the lipoprotein-associated phospholipase A2 to be measured at another site, different from the binding site of the lipoprotein-associated phospholipase A2 to be measured and the first anti-lipoprotein-associated phospholipase A2 antibodies. The reagent kit also comprises a displacing agent, so as to further increase the detection accuracy of the reagent kit.
    Type: Grant
    Filed: February 10, 2015
    Date of Patent: October 22, 2019
    Assignee: SHENZHEN NEW INDUSTRIES BIOMEDICAL ENGINEERING CO., LTD
    Inventors: Wei Rao, Jinyun Yuan, Qin Li, Ke Huang, Kai Luo, Dongxia Lin, Tinghua Li
  • Patent number: 10114030
    Abstract: Provided are a detection agent for detecting hydroxy vitamin D, preparation method thereof, and use thereof in 25-hydroxy vitamin D immunological detection. The detection agent comprises a conjugate formed by a 25-hydroxy vitamin D antigen derivative and protein carrier, and magnetic spheres coated by the conjugate. Also provided is a 25-hydroxy vitamin D detection kit comprising the detection agent.
    Type: Grant
    Filed: July 10, 2014
    Date of Patent: October 30, 2018
    Assignee: SHENZHEN NEW INDUSTRIES BIOMEDICAL ENGINEERING CO., LTD
    Inventors: Wei Rao, Tinghua Li, Kai Du, Jinyun Yuan, Kai Luo, Huiling Yu
  • Publication number: 20180231540
    Abstract: A reagent kit used for detecting gastrin-17, a preparation method, and a detection method for the reagent kit. The reagent kit comprises component A and component B, wherein component A is a first anti-gastrin-17 antibody marked with a trace marker or coated on magnetic spheres, and component B is a second gastrin-17 antibody or gastrin-17 coated on magnetic spheres or marked with a trace marker. Either one of component A and component B is marked with the trace marker, and the other one is coated on the magnetic spheres. The first gastrin-17 antibody and gastrin-17 binding site is different from the second gastrin-17 antibody and gastrin-17 binding site. The method using a double antibody sandwich method or a competition method to detect gastrin-17 accurately and sensitively measures the amount of gastrin-17 in a sample.
    Type: Application
    Filed: February 10, 2017
    Publication date: August 16, 2018
    Inventors: Wei RAO, Pu SUN, Yunxuan LI, Wang LIU, Yali YANG, Jinyun YUAN, Tinghua LI
  • Publication number: 20170363627
    Abstract: A reagent kit used for detecting lipoprotein-associated phospholipase A2, and a preparation method for the reagent kit. The reagent kit comprises one or a plurality of first anti-lipoprotein-associated phospholipase A2 antibodies used for binding lipoprotein-associated phospholipase A2 to be measured, and one or a plurality of second anti-lipoprotein-associated phospholipase A2 antibodies marked with a trace marker and binding with the lipoprotein-associated phospholipase A2 to be measured at another site, different from the binding site of the lipoprotein-associated phospholipase A2 to be measured and the first anti-lipoprotein-associated phospholipase A2 antibodies. The reagent kit also comprises a displacing agent, so as to further increase the detection accuracy of the reagent kit.
    Type: Application
    Filed: February 10, 2015
    Publication date: December 21, 2017
    Inventors: Wei RAO, Jinyun YUAN, Qin LI, Ke HUANG, Kai LUO, Dongxia LIN, Tinghua LI
  • Publication number: 20170305983
    Abstract: A cardiac troponin I ultra-sensitive detection reagent kit, a preparation method, and a detection method. The reagent kit comprises at least one first anti-cardiac troponin I antibody marked with a trace marker and at least one second anti-cardiac troponin I antibody coated on magnetic microspheres, the first anti-cardiac troponin I antibody and cardiac troponin I binding site being different from the second anti-cardiac troponin I antibody and cardiac troponin I binding site. The reagent kit may further comprise a diluent capable of significantly reducing non-specific binding in a detection process, so as to further increase the detection accuracy and sensitivity. The method using the reagent kit to detect cardiac troponin I sensitively and accurately detects the amount of cardiac troponin I in a sample, and provides more timely and reliable information for the early diagnosis and treatment of AMI.
    Type: Application
    Filed: February 10, 2015
    Publication date: October 26, 2017
    Applicant: SHENZHEN NEW INDUSTRIES BIOMEDICAL ENGINEERING CO., LTD
    Inventors: Wei RAO, Jinyun YUAN, Qin LI, Sheng WANG, Hong HU, Wu LI, Tinghua LI, Jinqiu FU
  • Publication number: 20170184615
    Abstract: Provided are a detection agent for detecting hydroxy vitamin D, preparation method thereof, and use thereof in 25-hydroxy vitamin D immunological detection. The detection agent comprises a conjugate formed by a 25-hydroxy vitamin D antigen derivative and protein carrier, and magnetic spheres coated by the conjugate. Also provided is a 25-hydroxy vitamin D detection kit comprising the detection agent.
    Type: Application
    Filed: July 10, 2014
    Publication date: June 29, 2017
    Inventors: Wei RAO, Tinghua LI, Kai DU, Jinyun YUAN, Kai LUO, Huiling YU