Patents by Inventor Jiquan OU

Jiquan OU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chromatographic method for isolating and purifying high-purity recombined human serum albumin
    Patent number: 10730926
    Abstract: Disclosed is a chromatographic method for isolating and purifying high-purity recombined human serum albumin, comprising: conducting cation-exchange chromatography on recombined human serum albumin, and adding alcohol to a buffer solution to remove endotoxin, so as to obtain a primary product I; under binding conditions, conducting anion/hydrophobic composite resin exchange chromatography on the primary product I to obtain an intermediate product II; conducting hydrophobic chromatography on the intermediate product II to obtain the target product, the purified high-purity recombined human serum albumin. The purity of the recombined human serum albumin obtained by isolating and purifying with the chromatographic method of the present invention is greater than 99.9999%, and the content of the endotoxin meets the criteria stipulated by Chinese pharmacopoeia.
    Type: Grant
    Filed: May 9, 2013
    Date of Patent: August 4, 2020
    Assignee: WUHAN HEALTHGEN BIOTECHNOLOGY CORP
    Inventors: Daichang Yang, Bo Shi, Qianni Shi, Jiquan Ou, Jingru Liu
  • CHROMATOGRAPHIC METHOD FOR ISOLATING AND PURIFYING HIGH-PURITY RECOMBINED HUMAN SERUM ALBUMIN
    Publication number: 20150329618
    Abstract: Disclosed is a chromatographic method for isolating and purifying high-purity recombined human serum albumin, comprising: conducting cation-exchange chromatography on recombined human serum albumin, and adding alcohol to a buffer solution to remove endotoxin, so as to obtain a primary product I; under binding conditions, conducting anion/hydrophobic composite resin exchange chromatography on the primary product I to obtain an intermediate product II; conducting hydrophobic chromatography on the intermediate product II to obtain the target product, the purified high-purity recombined human serum albumin. The purity of the recombined human serum albumin obtained by isolating and purifying with the chromatographic method of the present invention is greater than 99.9999%, and the content of the endotoxin meets the criteria stipulated by Chinese pharmacopoeia.
    Type: Application
    Filed: May 9, 2013
    Publication date: November 19, 2015
    Applicant: WUHAN HEALTHGEN BIOTECHNOLOGY CORP
    Inventors: Daichang YANG, Bo SHI, Qianni SHI, Jiquan OU, Jingru LIU