Patents by Inventor Jiri Adamec

Jiri Adamec has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Apparatus for Multiplex Extraction of Biological Samples and In-Transit Preparation of the Same
    Publication number: 20160089669
    Abstract: The invention relates to a device for the rapid simultaneous collection, and, optionally, treatment or standardization, of multiple aliquots of a liquid biological sample such as blood from a single source drop or sample portion, the device comprising device comprising a cover, a spreading layer comprising a macroporous membrane adjacent to the cover, where the spreading layer comprises a transport portion and at least one accumulation portion in fluid connection with the transport portion, and at least one collection portion in fluid connection with each accumulation portion.
    Type: Application
    Filed: September 28, 2015
    Publication date: March 31, 2016
    Inventors: Fred Regnier, Jinhee Kim, Jiri Adamec, Timothy E. Woenker, Richard P. Zoltek
  • Method for determining derivatized analytes in a separated biological fluid
    Patent number: 9068995
    Abstract: The present invention comprises methods for determining the presence, amount, or concentration of analytes of interest including Vitamin D and other secosteroids from biological samples, through derivatization, with improved speed and ease of analysis and improved sensitivity to mass spectrometry. In a preferred embodiment, the present invention comprises methods for determining the presence, amount, or concentration of analytes of interest, including Vitamin D and other secosteroids from whole human blood, through derivatization, and using a plasma collection device to facilitate collection, separation, and preparation of the sample for derivatization and analysis.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: June 30, 2015
    Inventors: Fred Regnier, Jinhee Kim, Jiri Adamec, Timothy E. Woenker, Richard P. Zoltek, Wenchu Yang
  • Method for Determining Derivatized Analytes in A Separated Biological Fluid
    Publication number: 20140273260
    Abstract: The present invention comprises methods for determining the presence, amount, or concentration of analytes of interest including Vitamin D and other secosteroids from biological samples, through derivatization, with improved speed and ease of analysis and improved sensitivity to mass spectrometry. In a preferred embodiment, the present invention comprises methods for determining the presence, amount, or concentration of analytes of interest, including Vitamin D and other secosteroids from whole human blood, through derivatization, and using a plasma collection device to facilitate collection, separation, and preparation of the sample for derivatization and analysis.
    Type: Application
    Filed: March 15, 2013
    Publication date: September 18, 2014
    Applicant: Novilytic, LLC
    Inventors: Fred Regnier, Jinhee Kim, Jiri Adamec, Timothy E. woenker, Richard P. Zoltek, Wenchu Yang
  • Group specific internal standard technology (GSIST) for simultaneous identification and quantification of small molecules
    Patent number: 8628977
    Abstract: Reagents and methods are provided that permit simultaneous analysis of multiple diverse small molecule analytes present in a complex mixture. Samples are labeled with chemically identical but isotopically distinct forms of the labeling reagent, and analyzed using mass spectrometry. A single reagent simultaneously derivatizes multiple small molecule analytes having different reactive functional groups.
    Type: Grant
    Filed: May 1, 2009
    Date of Patent: January 14, 2014
    Assignee: Purdue Research Foundation
    Inventors: Jiri Adamec, Wen-Chu Yang, Fred E. Regnier
  • GROUP SPECIFIC INTERNAL STANDARD TECHNOLOGY (GSIST) FOR SIMULTANEOUS IDENTIFICATION AND QUANTIFICATION OF SMALL MOLECULES
    Publication number: 20110183430
    Abstract: Reagents and methods are provided that permit simultaneous analysis of multiple diverse small molecule analytes present in a complex mixture. Samples are labeled with chemically identical but isotopically distinct forms of the labeling reagent, and analyzed using mass spectrometry. A single reagent simultaneously derivatizes multiple small molecule analytes having different reactive functional groups.
    Type: Application
    Filed: May 1, 2009
    Publication date: July 28, 2011
    Applicant: Purdue Research Foundation
    Inventors: Jiri Adamec, Wen-Chu Yang, Fred E. Regnier