Patents by Inventor Jiri Aubrecht

Jiri Aubrecht has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Assays for mutagenesis detection
    Patent number: 9193983
    Abstract: The disclosure provides methods, systems, and kits for assaying an agent for mutagenic properties. The methods systems and kits utilize a DEL selectable marker and a colorimetric detection systems. Also included are methods systems and kits that utilize a DEL selectable marker and a regent that detects mitochondrial activity.
    Type: Grant
    Filed: November 30, 2009
    Date of Patent: November 24, 2015
    Assignee: The Regents of the University of California
    Inventors: Robert H. Schiestl, Nikos Hontzeas, Jiri Aubrecht, Yelena O. Rivina
  • ASSAYS FOR MUTAGENESIS DETECTION
    Publication number: 20110065131
    Abstract: The disclosure provides methods, systems, and kits for assaying an agent for mutagenic properties. The methods systems and kits utilize a DEL selectable marker and a colorimetric detection systems. Also included are methods systems and kits that utilize a DEL selectable marker and a regent that detects mitochondrial activity.
    Type: Application
    Filed: November 30, 2009
    Publication date: March 17, 2011
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Robert H. Schiestl, Nikos Hontzeas, Kurt M. Hafer, Jiri Aubrecht, Yelena O. Rivina
  • Bioluminescent assays and bacterial strains useful therein
    Patent number: 6956113
    Abstract: The present invention relates to novel assays for assessing the degree to which a cell is metabolically active. Also provided, are mutagenicity assays and, more specifically, methods for determining whether a given agent is genotoxic. Embodiments of the assays employ a microorganism, or a mammalian cell, that has been genetically modified to produce light when the presence of test agent results in a mutation, e.g., reversion or forward, in the DNA of such microorganism or cell.
    Type: Grant
    Filed: December 21, 2001
    Date of Patent: October 18, 2005
    Assignee: Pfizer Inc.
    Inventors: Jiri Aubrecht, Warren W. Ku, Jeffery J. Osowski
  • Bioluminescent assays and cells useful therein
    Publication number: 20050148007
    Abstract: The present invention relates to novel bioluminescent assays and to cells and kits useful therein.
    Type: Application
    Filed: December 22, 2004
    Publication date: July 7, 2005
    Inventors: Jiri Aubrecht, Jeffery Osowski
  • Method for determining genotoxicity
    Publication number: 20030203388
    Abstract: The invention relates to methods for characterizing the genotoxicity of an agent.
    Type: Application
    Filed: April 24, 2003
    Publication date: October 30, 2003
    Applicant: Pfizer Inc.
    Inventor: Jiri Aubrecht
  • IN VIVO SELECTION
    Publication number: 20030032003
    Abstract: A method of selecting for cells in vivo is disclosed. The method includes the steps of providing in vivo cells which are resistant to a selecting substance and cells non-resistant to the selecting substance.
    Type: Application
    Filed: February 2, 2000
    Publication date: February 13, 2003
    Inventors: ROBERT H. SCHIESTL, JIRI AUBRECHT
  • Novel bioluminescent assays and bacterial strains useful therein
    Publication number: 20020192635
    Abstract: The present invention relates to novel assays for assessing the degree to which a cell is metabolically active. Also provided, are mutagenicity assays and, more specifically, methods for determining whether a given agent is genotoxic. Embodiments of the assays employ a microorganism, or a mammalian cell, that has been genetically modified to produce light when the presence of test agent results in a mutation, e.g., reversion or forward, in the DNA of such microorganism or cell.
    Type: Application
    Filed: December 21, 2001
    Publication date: December 19, 2002
    Inventors: Jiri Aubrecht, Warren W. Ku, Jeffery J. Osowski