Abstract: Disclosed is a method of preparing a medical preparation with a carrier based on hyaluronan and/or its derivatives, which can be used in the field of medicine and cosmetics. The medical preparation comprises a conjugate of hyaluronic acid and/or its derivative with a medical substance, according to the general formula A-S—N, where: A is the medical substance; S is the way of linking the medical substance with the carrier; and N is the carrier based on hyaluronic acid and/or its derivatives.

Abstract: The invention relates to two-component biodegradable core-sheath fibers comprising a combination of native and C11-C18 acylated hyaluronan or C11-C18 acylated hyaluronans. It further relates to method of preparation and use thereof, especially for controlled release of the active agent. Fibers may be further processed into the form of staple fibers, yarn, braided, woven, knitted and non-woven textiles.

Abstract: The invention relates to the biodegradable fibres which are based on hydrophobic derivatives of hylauronan, specifically on the base of the hyaluronan derivative C11-C18-acylated on hydroxyl groups of hyaluronic acid, and use thereof. Further the invention relates to the preparation of these fibres which is performed with the use of the wet spinning method in a coagulation bath comprising water solution of organic acid, with the production of continuous monofiles which can be thereafter processed to threads and further to textiles, knitted textiles, or nonwoven textiles. These textiles, knitted textiles or nonwoven textiles can be used for example for the production of implantable surgical material for human and veterinary medicine.

Abstract: The present invention relates to the preparation of textile processable endless monofilaments and multifilaments on the basis of hyaluronan which has been selectively oxidized to aldehyde in the position 6 of its/V-acetyl-D-glucosamine group and to the subsequent modification of such filaments with low molecular dihydrazides. The fibres as well as the fabrics, which are subsequently prepared from the former, exhibit a time-varying solubility in saline depending on the external modification of the fibres. After having been externally modified, the fibres as well as the fabrics exhibit a prolong period of transition into an evenly distributed gel layer. The externally modified fibrous materials retain their full biocompatibility.

Abstract: The invention relates to the method of the preparation of polysaccharide fibers based on hyaluronic acid, a compound comprising hyaluronic acid and metal ions, schizophylan, chitin/chitosan-glucan complex, a compound comprising chitin/chitosan-glucan complex and metal ions, internal mixture of chitin and chitosan, a compound comprising internal mixture of chitin and metal ions, sodium alginate, potassium alginate, ammonium alginate, xanthane, xanthane sodium salt, xanthane potassium salt, oxycellulose, oxycellulose sodium salt, oxycellulose potassium salt, carboxymethyl cellulose, carboxymethyl cellulose sodium salt, and carboxymethyl cellulose potassium salt, or a mixture of polysaccharides, in a non-stationary coagulation bath. Further the invention relates to covers of internal and external wounds and skin defects based on these fibers, and a method of production thereof, and the apparatus for the preparation of polysaccharide fibers.