Publication number: 20070249915
Abstract: The present invention provides a skin test method for predicting the formation of spots in the skin. This method judges skin to be susceptible to the formation of spots in the case expression in the epidermis of MCP-2 gene, a polynucleotide capable of hybridizing under highly stringent conditions to mouse AK012157 gene, human FLJ21763 gene or rat S74257 gene, or Mcp9, Mcp10, Isg15, Usp18, Oas12, Gbp2, Gtpi, Ifi47, Igtp, Tgtp, Sprr2A, Krt2-6b, Cdk5rap2, Mef2C, Gsta4, Osf2, Tnc, Igfbp6, Ppicap or Mm. 74656 gene, is increased as compared with normal expression in the epidermis.
Type:
Application
Filed:
September 30, 2004
Publication date:
October 25, 2007
Applicant:
Shiseido Company, Ltd.
Inventors:
Hirofumi Aoki, Tatsuhiro Kodama, Kiyotaka Hasegawa, Kentaro Kajiya, Yumiko Ishimatatsu, Masashi Ogou, Seiichi Yoshida, Jiro Kishimoto, Osamu Moro