Patents by Inventor Jitendra Maganbhai Gajera

Jitendra Maganbhai Gajera has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparation of grapiprant
    Patent number: 11254675
    Abstract: The invention relates to process for the preparation of grapiprant and its intermediates thereof. The invention also relates to grapiprant having a purity 98% or more and compounds of Formula (A), (B), (C) and (D) in an amount of 0.5 or less, relative to grapiprant, by area percentage of HPLC. The invention also relates to an amorphous form of grapiprant and process for preparation thereof.
    Type: Grant
    Filed: August 12, 2020
    Date of Patent: February 22, 2022
    Assignee: CADILA HEALTHCARE LIMITED
    Inventors: Kumar Kamlesh Singh, Jitendra Maganbhai Gajera, Sumer Singh Chundavat, Dipak Ambalal Patel
  • PROCESS FOR PREPARATION OF GRAPIPRANT
    Publication number: 20210347776
    Abstract: The invention relates to process for the preparation of grapiprant and its intermediates thereof. The invention also relates to grapiprant having a purity 98% or more and compounds of Formula (A), (B), (C) and (D) in an amount of 0.5 or less, relative to grapiprant, by area percentage of HPLC. The invention also relates to an amorphous form of grapiprant and process for preparation thereof.
    Type: Application
    Filed: July 23, 2021
    Publication date: November 11, 2021
    Applicant: CADILA HEALTHCARE LIMITED
    Inventors: Kumar Kamlesh SINGH, Jitendra Maganbhai GAJERA, Sumer Singh CHUNDAVAT, Dipak Ambalal PATEL
  • PROCESS FOR PREPARATION OF GRAPIPRANT
    Publication number: 20210079000
    Abstract: The invention relates to process for the preparation of grapiprant and its intermediates thereof. The invention also relates to grapiprant having a purity 98% or more and compounds of Formula (A), (B), (C) and (D) in an amount of 0.5 or less, relative to grapiprant, by area percentage of HPLC. The invention also relates to an amorphous form of grapiprant and process for preparation thereof.
    Type: Application
    Filed: August 12, 2020
    Publication date: March 18, 2021
    Applicant: CADILA HEALTHCARE LIMITED
    Inventors: Kumar Kamlesh SINGH, Jitendra Maganbhai GAJERA, Sumer Singh CHUNDAVAT, Dipak Ambalal PATEL
  • Amorphous vortioxetine and salts thereof
    Patent number: 10414741
    Abstract: The present invention relates to an amorphous vortioxetine and salts thereof. In particular, the invention relates to a process for the preparation of an amorphous vortioxetine hydrobromide. Further, the invention also relates to a process for preparation of amorphous vortioxetine free base. The invention also relates to pharmaceutical compositions comprising an amorphous vortioxetine or hydrobromide salt thereof for oral administration for treatment of major depressive disorder (MDD) and generalized anxiety disorder (GAD).
    Type: Grant
    Filed: September 30, 2014
    Date of Patent: September 17, 2019
    Assignee: CADILA HEALTHCARE LIMITED
    Inventors: Shri Prakash Dhar Dwivedi, Kumar Kamlesh Singh, Jitendra Maganbhai Gajera, Dinesh Kumar Raikwar, Brij Khera
  • Amorphous form of linagliptin and process for preparation thereof
    Patent number: 9879011
    Abstract: The present invention relates to an amorphous form of linagliptin and processes for the preparation thereof. The invention also relates to a pharmaceutical composition comprising a therapeutically effective amount of an amorphous form of linagliptin and use of the composition for treatment of diabetes especially type-I or type-II, prediabetes or reduction of glucose tolerance.
    Type: Grant
    Filed: March 12, 2013
    Date of Patent: January 30, 2018
    Assignee: Cadila Healthcare Limited
    Inventors: Shriprakash Dhar Dwivedi, Ashok Prasad, Kuldeep Natwarlal Jain, Kumar Kamlesh Singh, Jitendra Maganbhai Gajera
  • AN AMORPHOUS VORTIOXETINE AND SALTS THEREOF
    Publication number: 20160214949
    Abstract: The present invention relates to an amorphous vortioxetine and salts thereof. In particular, the invention relates to a process for the preparation of an amorphous vortioxetine hydrobromide. Further, the invention also relates to a process for preparation of amorphous vortioxetine free base. The invention also relates to pharmaceutical compositions comprising an amorphous vortioxetine or hydrobromide salt thereof for oral administration for treatment of major depressive disorder (MDD) and generalized anxiety disorder (GAD).
    Type: Application
    Filed: September 30, 2014
    Publication date: July 28, 2016
    Inventors: Shri Prakash Dhar DWIVEDI, Kumar Kamlesh SINGH, Jitendra Maganbhai GAJERA, Dinesh Kumar RAIKWAR, Brij KHERA
  • AMORPHOUS FORM OF LINAGLIPTIN AND PROCESS FOR PREPARATION THEREOF
    Publication number: 20150051228
    Abstract: The present invention relates to an amorphous form of linagliptin and processes for the preparation thereof. The invention also relates to a pharmaceutical composition comprising therapeutically effective amount of an amorphous form of linagliptin and use of said composition for treatment of diabetes especially type-I or type-II, prediabetes or reduction of glucose tolerance.
    Type: Application
    Filed: March 12, 2013
    Publication date: February 19, 2015
    Applicant: CADILA HEALTHCARE LIMITED
    Inventors: Shriprakash Dhar Dwivedi, Ashok Prasad, Kuldeep Natwarlal Jain, Kumar Kamlesh Singh, Jitendra Maganbhai Gajera
  • AMORPHOUS FORM OF APIXABAN, PROCESS OF PREPARATION AND COMPOSITIONS THEREOF
    Publication number: 20150018386
    Abstract: The present invention discloses an amorphous form of apixaban, process of preparation and compositions thereof.
    Type: Application
    Filed: March 5, 2013
    Publication date: January 15, 2015
    Inventors: Shriprakash Dhar Dwivedi, Kamlesh Kumar Singh, Jitendra Maganbhai Gajera, Nitin Tandon, Digambar Ware
  • PROCESS FOR THE PREPARATION AND PURIFICATION OF AZILSARTAN MEDOXOMIL
    Publication number: 20140113942
    Abstract: The present invention relates to process an improved process for the preparation of azilsartan medoxomil. In particular, the field of invention relates to a process for purification of azilsartan medoxomil. More particularly, the invention relates to an improved process for preparation of azilsartan medoxomil and its pharmaceutically acceptable salts.
    Type: Application
    Filed: October 11, 2013
    Publication date: April 24, 2014
    Applicant: CADILA HEALTHCARE LIMITED
    Inventors: Shriprakash Dhar DWIVEDI, Kumar Kamlesh SINGH, Jitendra Maganbhai GAJERA
  • Processes for preparing 6-(difluoromethoxy)[1]benzofuro[3,2-]pyridine-9-carbaldehyde, a novel intermediate for the synthesis of PDE IV inhibitors
    Patent number: 8524905
    Abstract: The present invention relates to novel processes for preparing 6-(difluoromethoxy)[1]benzofuro[3,2-c]pyridine-9-carbaldehyde, which is a novel and useful intermediate for preparing compounds with PDE4 inhibitory activity, such as 3,5-dichloro-4-(6-difluoromethoxybenzo[4,5]furo[3,2-c]pyridin-9-ylcarboxamido)-1-pyridiniumolate.
    Type: Grant
    Filed: May 21, 2008
    Date of Patent: September 3, 2013
    Assignee: Glenmark Pharmaceuticals S.A.
    Inventors: Laxmikant Atmaram Gharat, Jitendra Maganbhai Gajera, Sandip Damodar Patil, Suresh M. Kadam
  • NOVEL PROCESSES FOR PREPARING 6-(DIFLUOROMETHOXY)[1]BENZOFURO[3,2-C]PYRIDINE-9-CARBALDEHYDE, A NOVEL INTERMEDIATE FOR THE SYNTHESIS OF PDE IV INHIBITORS
    Publication number: 20100168151
    Abstract: The present invention relates to novel processes for preparing 6-(difluoromethoxy)[1] benzofuro[3,2-c]pyridine-9-carbaldehyde, which is a novel and useful intermediate for preparing compounds with PDE4 inhibitory activity, such as 3,5-dichloro-4-(6-difluoromethoxybenzo[4,5]furo[3,2-c]pyridin-9-ylcarboxamido)-1-pyridiniumolate.
    Type: Application
    Filed: May 21, 2008
    Publication date: July 1, 2010
    Applicant: Glenmark Pharmaceuticals, S.A.
    Inventors: Laxmikant Atmaram Gharat, Jitendra Maganbhai Gajera, Sandip Damodar Patil, Suresh M. Kadam