Patents by Inventor Jiuhui ZHANG

Jiuhui ZHANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Phenyl containing compound, intermediate thereof, preparation method therefor and application thereof
    Patent number: 11667604
    Abstract: A phenyl-containing compound, an intermediate thereof, a preparation method therefor and an application thereof. Provided is a compound represented by formula I or a pharmaceutically acceptable salt thereof, where R1, R2, R3, R4 and R5 are independently hydrogen, C1-C6 alkyl, C1-C6 alkoxy or C(?O)OR8; where R8 is C1-C4 alkyl; R6 is (II), (III) or (IV); and R7 is —OH, —NH2, —NHCH3, —N(CH3)2 or C1-4 alkoxy. The compound has a low critical micelle concentration (CMC) and good dilution resistance and is capable of enclosing an insoluble drug to form a small-molecule micelle having a high drug loading capacity and good stability.
    Type: Grant
    Filed: July 14, 2020
    Date of Patent: June 6, 2023
    Assignees: SHANGHAI MODERN PHARMACEUTICAL ENGINEERING RESEARCH CENTER CO., LTD., SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY
    Inventors: Jun He, Zhefeng Wang, Yuezhu Zhao, Yani Yang, Qinghui Fu, Wei Bian, Yuan Zhao, Chen Ge, Yue Zhang, Bing Yi, Minghao Niu, Jiuhui Zhang
  • Phenyl Containing Compound, Intermediate Thereof, Preparation Method Therefor and Application Thereof
    Publication number: 20220274920
    Abstract: A phenyl-containing compound, an intermediate thereof, a preparation method therefor and an application thereof. Provided is a compound represented by formula I or a pharmaceutically acceptable salt thereof, where R1, R2, R3, R4 and R5 are independently hydrogen, C1-C6 alkyl, C1-C6 alkoxy or C(?O)OR8; where R8 is C1-C4 alkyl; R6 is (II), (III) or (IV); and R7 is —OH, —NH2, —NHCH3, —N(CH3)2 or C1-4 alkoxy. The compound has a low critical micelle concentration (CMC) and good dilution resistance and is capable of enclosing an insoluble drug to form a small-molecule micelle having a high drug loading capacity and good stability.
    Type: Application
    Filed: July 14, 2020
    Publication date: September 1, 2022
    Inventors: Jun HE, Zhefeng WANG, Yuezhu ZHAO, Yani YANG, Qinghui FU, Wei BIAN, Yuan ZHAO, Chen GE, Yue ZHANG, Bing YI, Minghao NIU, Jiuhui ZHANG