Patents by Inventor Jiuqing ZHANG

Jiuqing ZHANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • WEE1 INHIBITOR AND PREPARATION AND USE THEREOF
    Publication number: 20220194960
    Abstract: The present invention relates to a WEE1 inhibitor, and the preparation and use thereof. The WEE1 inhibitor of the present invention is a compound of Formula I or a compound of Formula II, or a pharmaceutically acceptable salt, solvate, polymorph or tautomer thereof. The present invention also provides use of the WEE1 inhibitor in the manufacture of a medicament for the treatment of a disease associated with WEE1 activity. The WEE1 inhibitor provided by the present invention can effectively treat the disease associated with WEE1 activity.
    Type: Application
    Filed: March 20, 2020
    Publication date: June 23, 2022
    Inventors: Yan Zhu, Jinsuo Yao, Yeliu Wang, Qin Yan, Weinan He, Changjun Chen, Xianxing Shang, Jijun Li, Yinghui Sun, Hongjuan Li, Chang Lu, Jiuqing Zhang, Deng Hou, Xiaojun Zhang, Qichao Liu
  • FGFR4 KINASE INHIBITOR AND PREPARATION METHOD THEREFOR AND USE THEREOF
    Publication number: 20220185811
    Abstract: The invention relates to an FGFR4 kinase inhibitor, and the preparation method and use thereof. The invention relates to a compound of Formula I, or a pharmaceutically acceptable salt, solvate, polymorph or tautomer thereof, and use thereof in the manufacture of a medicament for the treatment of an FGFR4 mediated disease.
    Type: Application
    Filed: March 6, 2020
    Publication date: June 16, 2022
    Inventors: Jinghan WANG, Jinsuo YAO, Xiaowei DUAN, Baokun YUAN, Xijie LIU, Nan JIAO, Wangyang MIN, Ying SUN, Chang LU, Yinghui SUN, Jiuqing ZHANG, Yeling JI, Deng HOU
  • Macrocycle containing aminopyrazole and pyrimidine and pharmaceutical composition and use thereof
    Patent number: 11098060
    Abstract: The present application relates to a macrocycle containing aminopyrazole and pyrimidine, which is represented by formula (I), a pharmaceutical composition thereof, and a use thereof in inhibiting tropomyosin receptor kinase (Trk) activity and in treating diseases in mammals that are mediated by Trk.
    Type: Grant
    Filed: August 23, 2018
    Date of Patent: August 24, 2021
    Assignees: CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD., CENTAURUS BIOPHARMA CO., LTD., LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.
    Inventors: Liguang Dai, Xiaowei Duan, Yanqing Yang, Xijie Liu, Hongjuan Li, Na Zhao, Yinghui Sun, Fansheng Kong, Jiuqing Zhang, Yizhong Zhu, Ling Yang, Fei Liu
  • MACROCYCLE CONTAINING AMINOPYRAZOLE AND PYRIMIDINE AND PHARMACEUTICAL COMPOSITION AND USE THEREOF
    Publication number: 20200291042
    Abstract: The present application relates to a macrocycle containing aminopyrazole and pyrimidine, which is represented by formula (1), a pharmaceutical composition thereof, and a use thereof in inhibiting tropornyosin receptor kinase (Trk) activity and in treating diseases in mammals that are mediated by Trk.
    Type: Application
    Filed: August 23, 2018
    Publication date: September 17, 2020
    Inventors: Liguang DAI, Xiaowei DUAN, Yanqing YANG, Xijie LIU, Hongjuan LI, Na ZHAO, Yinghui SUN, Fansheng KONG, Jiuqing ZHANG, Yizhong ZHU, Ling YANG, Fei LIU