Abstract: The design, synthesis, and biological evaluation of a new family of highly effective conjugate compounds, including dendrimeric moieties and branched structures, are described. Pharmaceutical compositions including the subject dendrimeric conjugates and methods of using the same are also provided. Methods of using the subject dendrimeric conjugates include delivering a cargo moiety conjugated to the dendrimeric moieties and branched structures to a cell under suitable conditions. In certain embodiments, the cell is a bacterial cell population, and the subject compounds reduce the bacterial cell population. In certain embodiments of the methods, the subject compound is capable of eradicating one or more of Gram-positive bacteria, mycobacteria, and Gram-negative bacteria. In certain embodiments of the methods, the subject compound is capable of eradicating bacterial biofilms. Methods of using the subject dendrimeric conjugates include treating a subject for a disease or condition.

Abstract: A drop box includes two cabinets each including an accommodating space and a bottom cabinet door below the accommodating space, and a locking member arranged at a bottom end of the two cabinets. The locking member is configured to be in a first, a second, and a third operation statuses. In the first operation status, the locking member contacts the bottom cabinet door of each of the two cabinets. In the second operation status, the locking member contacts the bottom cabinet door of one of the two cabinets and is separated from the bottom cabinet door of another one of the two cabinets. In the third operation status, the locking member is separated from the bottom cabinet door of each of the two cabinets.