Abstract: This application provides an application of a reagent for quantitative detection of pyroglutamyl aminopeptidase in the diagnosis of rheumatoid arthritis (RA), where the reagent is a reagent for quantitative detection of pyroglutamyl aminopeptidase gene mRNA, a reagent for quantitative detection of pyroglutamyl aminopeptidase protein or a combination thereof. The quantitative detection is performed by enzyme-linked immunosorbent assay, Western blot, immunohistochemistry, a quantitative fluorescent polymerase chain reaction, mass spectrometry, or a combination thereof. A system for diagnosis of rheumatoid arthritis is also provided, including a sample collection module, a sample detection module and a data analysis module. The sample collection module is configured to collect a biological sample. The sample detection module is configured to quantitatively detect an expression level of pyroglutamyl aminopeptidase in vitro.

Abstract: Disclosed are a self-closing water saving device, method, and toilet. The self-closing water saving device for mounting in a tank of a toilet bowl is used for supplying water to the tank, and is characterized by comprising: a water inlet adapted to be connected to an external water source, a water outlet adapted to provide water to the tank, and a jet-propelling port for jetting water to the bottom of a water trap of the toilet bowl or the bottom of a sewer; wherein, when the tank discharges water to the water trap, the water jetted from the jet-propelling port is used to propel the water which is discharged from the tank and flows into the water trap, the bottom of the water trap, or the bottom of the sewer.

Abstract: Disclosed are a self-closing water saving device, method, and toilet. The self-closing water saving device for mounting in a tank of a toilet bowl is used for supplying water to the tank, and is characterized by comprising: a water inlet adapted to be connected to an external water source, a water outlet adapted to provide water to the tank, and a jet-propelling port for jetting water to the bottom of a water trap of the toilet bowl or the bottom of a sewer; wherein, when the tank discharges water to the water trap, the water jetted from the jet-propelling port is used to propel the water which is discharged from the tank and flows into the water trap, the bottom of the water trap, or the bottom of the sewer.