Abstract: A method for enhancing oil recovery in huff-puff oil production of tight oil from a fractured horizontal well by an optimized reservoir pressure, washing the horizontal well by sand flushing, injecting water into the reservoir to increase the stratum pressure around the horizontal well, and stopping the water injection when the pressure retention level is 100% at end stage of the water injection period. The method for enhancing oil recovery in huff-puff oil production of tight oil from a fractured horizontal well enables the crude oil in the pores of the matrix in the tight reservoir rock developed by the natural fracture to be further recovered. Comprehensive utilization of stratum energy boost, and imbibition replacement between the injected water and the reservoir crude oil improves the single-well production to enhance the oil recovery of a tight oil reservoir.

Abstract: A method for enhancing oil recovery in huff-puff oil production of tight oil from a fractured horizontal well by an optimized reservoir pressure, washing the horizontal well by sand flushing, injecting water into the reservoir to increase the stratum pressure around the horizontal well, and stopping the water injection when the pressure retention level is 100% at end stage of the water injection period. The method for enhancing oil recovery in huff-puff oil production of tight oil from a fractured horizontal well enables the crude oil in the pores of the matrix in the tight reservoir rock developed by the natural fracture to be further recovered. Comprehensive utilization of stratum energy boost, and imbibition replacement between the injected water and the reservoir crude oil improves the single-well production to enhance the oil recovery of a tight oil reservoir.

Abstract: This invention relates to a method of treating B cell malignancies, which involves administering to a subject a compound having a structure of formula (I) to cause cell death of a B cell malignancy, thereby treating the B cell malignancy in the subject. Also disclosed are a method of causing cell death of malignant B cells, pharmaceutical compositions and therapeutic systems comprising a compound having a structure of formula (I), and a compound having a structure of formula (I).

Abstract: This invention relates to a method of treating B cell malignancies, which involves administering to a subject a compound having a structure of formula (I) to cause cell death of a B cell malignancy, thereby treating the B cell malignancy in the subject. Also disclosed are a method of causing cell death of malignant B cells, pharmaceutical compositions and therapeutic systems comprising a compound having a structure of formula (I), and a compound having a structure of formula (I).

Abstract: The present invention is directed to methods of causing malignant B-cells and treating malignant B-cells. These methods involve the use of an inhibitor of PKK activity, whether active directly against PKK or effective to knockdown PKK expression, which when introduced into a malignant B cell (or administered to a patient) is effective to cause cell death of the malignant B cell, thereby treating the B-cell malignancy.

Abstract: The present invention is directed to methods of causing malignant B-cells and treating malignant B-cells. These methods involve the use of an inhibitor of PKK activity, whether active directly against PKK or effective to knockdown PKK expression, which when introduced into a malignant B cell (or administered to a patient) is effective to cause cell death of the malignant B cell, thereby treating the B-cell malignancy.

Abstract: A composition is provided that inhibits DNA replication in activated cell-free extracts of Xenopus eggs, which is prepared by a process comprising subjecting homogenates of Xenopus ovaries to a series of chromatographic separations so as to isolate a purified fraction comprising a protein having a molecular weight of about 245 kDa.